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GDF6: Function & Overview

Growth differentiation factor 6 (GDF6) is a protein that in humans is encoded by the GDF6 gene.

Language: English [EN]
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GDF6 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around GDF6.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
90
Concept neighborhoods
8
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 8 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, growth differentiation factor 6, SYNS4
Band
8q22.1 · 4|4 A1
Bgee
placenta · gonad · ventricular zone · gallbladder · right auricle of heart
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GDF6 connects Entity context

The extracted context around GDF6 shows recurring relationship patterns in the source. For example, GDF6 → activin receptor signaling pathway, apoptotic process, BMP signaling pathway, cell development, cytokine activity, extracellular region, extracellular space, fat cell differentiation, growth factor activity, multicellular organism development, pathway-restricted SMAD protein phosphorylation, positive regulation of chondrocyte differentiation, positive regulation of neuron differentiation, positive regulation of p38MAPK cascade, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-templated, protein binding, protein homodimerization activity, regulation of apoptotic process, regulation of MAPK cascade Another extracted example is GDF6 → Achilles tendon, auditory ossicle, embryo, gallbladder, ganglion, gastric mucosa, genital tubercle, gonad, incus, Jacobson's organ, left coronary artery, malleus, placenta, right auricle of heart, right coronary artery, sensory ganglion, smooth muscle tissue, stapes, trigeminal ganglion, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

GDF6

Top relations

Gene ontology · 24
GDF6 → activin receptor signaling pathway, apoptotic process, BMP signaling pathway, cell development, cytokine activity, extracellular region, extracellular space, fat cell differentiation, growth factor activity, multicellular organism development, pathway-restricted SMAD protein phosphorylation, positive regulation of chondrocyte differentiation, positive regulation of neuron differentiation, positive regulation of p38MAPK cascade, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-templated, protein binding, protein homodimerization activity, regulation of apoptotic process, regulation of MAPK cascade
Bgee · 20
GDF6 → Achilles tendon, auditory ossicle, embryo, gallbladder, ganglion, gastric mucosa, genital tubercle, gonad, incus, Jacobson's organ, left coronary artery, malleus, placenta, right auricle of heart, right coronary artery, sensory ganglion, smooth muscle tissue, stapes, trigeminal ganglion, ventricular zone
RNA expression pattern · 20
GDF6 → Achilles tendon, auditory ossicle, embryo, gallbladder, ganglion, gastric mucosa, genital tubercle, gonad, incus, Jacobson's organ, left coronary artery, malleus, placenta, right auricle of heart, right coronary artery, sensory ganglion, smooth muscle tissue, stapes, trigeminal ganglion, ventricular zone
related to Function · 6
GDF6 → BMPs, By, Grebe, Growth, It, Through
Band · 2
GDF6 → 4|4 A1, 8q22.1
Chr. · 2
GDF6 → Chromosome 4 (mouse), Chromosome 8 (human)
End · 2
GDF6 → 9,862,345 bp, 96,160,806 bp
Aliases · 1
GDF6 → GDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, growth differentiation factor 6, SYNS4
BioGPS · 1
GDF6 → n/a
Databases · 1
GDF6 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene growth factor chr human band differentiation chromosome protein development location mouse transforming beta function patterning bone proteins developing

GDF6 relationships Subject–Predicate–Object triples

TTTA extracted 90 structured relationships around GDF6. Examples in this analysis include GDF6 → Aliases → GDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, growth differentiation factor 6, SYNS4 and GDF6 → Band → 8q22.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GDF6AliasesGDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, growth differentiation factor 6, SYNS41.00infobox
GDF6Band8q22.11.00infobox
GDF6Band4|4 A11.00infobox
GDF6Bgeeplacenta1.00infobox
GDF6Bgeegonad1.00infobox
GDF6Bgeeventricular zone1.00infobox
GDF6Bgeegallbladder1.00infobox
GDF6Bgeeright auricle of heart1.00infobox
GDF6Bgeegastric mucosa1.00infobox
GDF6Bgeeright coronary artery1.00infobox
GDF6BgeeAchilles tendon1.00infobox
GDF6Bgeesmooth muscle tissue1.00infobox
GDF6Bgeeleft coronary artery1.00infobox
GDF6Bgeeauditory ossicle1.00infobox
GDF6Bgeestapes1.00infobox
GDF6Bgeeincus1.00infobox
GDF6Bgeemalleus1.00infobox
GDF6Bgeeganglion1.00infobox
GDF6Bgeeembryo1.00infobox
GDF6BgeeJacobson's organ1.00infobox
GDF6Bgeesensory ganglion1.00infobox
GDF6Bgeegenital tubercle1.00infobox
GDF6Bgeetrigeminal ganglion1.00infobox
GDF6BioGPSn/a1.00infobox
GDF6Chr.Chromosome 8 (human)1.00infobox
GDF6Chr.Chromosome 4 (mouse)1.00infobox
GDF6DatabasesNCBI: entry; OMA: entry1.00infobox
GDF6End96,160,806 bp1.00infobox
GDF6End9,862,345 bp1.00infobox
GDF6EnsemblENSG000001564661.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GDF6 bring nearby vocabulary together. In this analysis, examples include Gene, Growth and Bone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GDF6
    • Gene
    • Growth
    • Bone
    • Developing
    • Embryos
    • Patterning
    • Protein
    • Directly
    • Encoded
    • Epidermis
    • Expression
    • Function
  • gdf6
    • Gene
    • Growth
    • Bone
    • Developing
    • Embryos
    • Patterning
    • Protein
    • Directly
    • Encoded
    • Epidermis
    • Expression
    • Function
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Growth
    • End
    • Function
    • Mouse
    • Development
    • Protein
    • Band
  • transforming growth factor beta superfamily
    • Beta
    • Cell
    • Growth
    • Regulation
    • Superfamily
    • Transforming
    • Development
    • Proteins
    • Protein
    • Factor
    • Function
    • Gene
  • bone morphogenetic proteins
    • Patterning
    • Regulate
    • May
    • Morphogenetic
    • Proteins
    • Regulation
    • Superfamily
    • Transforming
    • Mouse
    • Neural
    • Gdf6
    • Cell
  • function
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Growth
    • Beta
    • Cell
    • End
    • Expression
    • Gene
    • May
  • protein
    • Regulate
    • Regulation
    • Superfamily
    • Transforming
    • Developing
    • Embryos
    • Patterning
    • Proteins
  • epidermis
    • Directly
    • Joint
    • Neural
    • Patterning
    • Gdf6
    • Gene

Connections between topic areas Semantic bridges

For GDF6, one of the stronger structural bridges in this analysis connects GDF6 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GDF6Function · splits 4 ⟂ 9
GDF6Overview · splits 10 ⟂ 3

Map overview Semantic statistics

GDF6

Nodes13
Edges12
Triples90
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around GDF6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GDF6 · EN edition · Analysis: TopicsToTalkAbout

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