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BMPR1B: Clinical significance, Function & Overview

Bone morphogenetic protein receptor type-1B also known as CDw293 (cluster of differentiation w293) is a protein that in humans is encoded by the BMPR1B gene.

Language: English [EN]
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BMPR1B topic overview

The analysis highlights Clinical significance, Function and Overview as prominent areas in the source structure around BMPR1B.

Related topics
6
Source areas
3
Connected nodes
9
Extracted relationships
142
Concept neighborhoods
7
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 3 topics
Clinical significance · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.30
Aliases
BMPR1B, ALK-6, ALK6, CDw293, AMDD, BDA1D, BDA2, bone morphogenetic protein receptor type 1B, AMD3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MDY
Band
4q22.3 · 3|3 H1
Bgee
Achilles tendon · bronchial epithelial cell · tail of epididymis · testicle · buccal mucosa cell
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BMPR1B connects Entity context

The extracted context around BMPR1B shows recurring relationship patterns in the source. For example, BMPR1B → ATP binding, BMP signaling pathway, camera-type eye development, cartilage condensation, cartilage development, cell differentiation, cellular response to BMP stimulus, cellular response to growth factor stimulus, chondrocyte development, chondrocyte differentiation, dendrite, dorsal/ventral pattern formation, endochondral bone morphogenesis, eye development, growth factor binding, HFE-transferrin receptor complex, inflammatory response, integral component of membrane, integral component of plasma membrane, kinase activity Another extracted example is BMPR1B → Achilles tendon, bronchial epithelial cell, buccal mucosa cell, cumulus cell, entorhinal cortex, lobe of prostate, lumbar subsegment of spinal cord, optic stalk, primary oocyte, prostate, renal medulla, right uterine tube, secondary oocyte, seminal vesicula, stria vascularis, tail of epididymis, testicle, trigeminal ganglion, vestibular sensory epithelium, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

BMPR1B

Top relations

Gene ontology · 54
BMPR1B → ATP binding, BMP signaling pathway, camera-type eye development, cartilage condensation, cartilage development, cell differentiation, cellular response to BMP stimulus, cellular response to growth factor stimulus, chondrocyte development, chondrocyte differentiation, dendrite, dorsal/ventral pattern formation, endochondral bone morphogenesis, eye development, growth factor binding, HFE-transferrin receptor complex, inflammatory response, integral component of membrane, integral component of plasma membrane, kinase activity
Bgee · 20
BMPR1B → Achilles tendon, bronchial epithelial cell, buccal mucosa cell, cumulus cell, entorhinal cortex, lobe of prostate, lumbar subsegment of spinal cord, optic stalk, primary oocyte, prostate, renal medulla, right uterine tube, secondary oocyte, seminal vesicula, stria vascularis, tail of epididymis, testicle, trigeminal ganglion, vestibular sensory epithelium, zygote
RNA expression pattern · 20
BMPR1B → Achilles tendon, bronchial epithelial cell, buccal mucosa cell, cumulus cell, entorhinal cortex, lobe of prostate, lumbar subsegment of spinal cord, optic stalk, primary oocyte, prostate, renal medulla, right uterine tube, secondary oocyte, seminal vesicula, stria vascularis, tail of epididymis, testicle, trigeminal ganglion, vestibular sensory epithelium, zygote
related to External links · 8
BMPR1B → Human BMPR1B, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, UCSC Genome Browser, United States National Library
related to Function · 8
BMPR1B → BMP, BMPs, II, TGF-beta, The, The BMPR1B, These, Type II
related to Clinical significance · 5
BMPR1B → BMPR1A, GDF5, In, Mutations, Unlike BMPR1A
Band · 2
BMPR1B → 3|3 H1, 4q22.3
Chr. · 2
BMPR1B → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
BMPR1B → 141,875,186 bp, 95,158,448 bp
is a · 2
BMPR1B → major transducer of signals in these condensations as demonstrated in experiments using constitutively active BMPR1B receptors, more effective transducer of GDF5 than BMPR1A

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp gene receptor chr protein band bone chromosome location type receptors formation morphogenetic mouse serine threonine ii cdw293 differentiation

BMPR1B relationships Subject–Predicate–Object triples

TTTA extracted 142 structured relationships around BMPR1B. Examples in this analysis include BMPR1B → 2.7.11.30 → ↗ and BMPR1B → Aliases → BMPR1B, ALK-6, ALK6, CDw293, AMDD, BDA1D, BDA2, bone morphogenetic protein receptor type 1B, AMD3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BMPR1B2.7.11.301.00infobox
BMPR1BAliasesBMPR1B, ALK-6, ALK6, CDw293, AMDD, BDA1D, BDA2, bone morphogenetic protein receptor type 1B, AMD31.00infobox
BMPR1BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MDY1.00infobox
BMPR1BBand4q22.31.00infobox
BMPR1BBand3|3 H11.00infobox
BMPR1BBgeeAchilles tendon1.00infobox
BMPR1BBgeebronchial epithelial cell1.00infobox
BMPR1BBgeetail of epididymis1.00infobox
BMPR1BBgeetesticle1.00infobox
BMPR1BBgeebuccal mucosa cell1.00infobox
BMPR1BBgeeseminal vesicula1.00infobox
BMPR1BBgeeentorhinal cortex1.00infobox
BMPR1BBgeerenal medulla1.00infobox
BMPR1BBgeetrigeminal ganglion1.00infobox
BMPR1BBgeeright uterine tube1.00infobox
BMPR1BBgeecumulus cell1.00infobox
BMPR1BBgeeprimary oocyte1.00infobox
BMPR1BBgeesecondary oocyte1.00infobox
BMPR1BBgeeoptic stalk1.00infobox
BMPR1BBgeezygote1.00infobox
BMPR1BBgeelumbar subsegment of spinal cord1.00infobox
BMPR1BBgeeprostate1.00infobox
BMPR1BBgeevestibular sensory epithelium1.00infobox
BMPR1BBgeestria vascularis1.00infobox
BMPR1BBgeelobe of prostate1.00infobox
BMPR1BBioGPSn/a1.00infobox
BMPR1BChr.Chromosome 4 (human)1.00infobox
BMPR1BChr.Chromosome 3 (mouse)1.00infobox
BMPR1BDatabasesNCBI: entry; OMA: entry1.00infobox
BMPR1BEnd95,158,448 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BMPR1B bring nearby vocabulary together. In this analysis, examples include Protein, Receptor and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BMPR1B
    • Protein
    • Receptor
    • Gene
    • Human
    • Morphogenetic
    • Bone
    • Location
    • Activity
    • Cdw293
    • Differentiation
    • Function
    • Search
  • bmpr1b
    • Protein
    • Receptor
    • Gene
    • Human
    • Morphogenetic
    • Bone
    • Location
    • Activity
    • Cdw293
    • Differentiation
    • Function
    • Search
  • cluster of differentiation
    • Morphogenetic
    • Bmp
    • Protein
    • Transmembrane
    • Receptor
    • Activity
    • Binding
    • Domain
    • End
    • Endochondral
    • Function
    • Gene
  • protein
    • Activity
    • Function
    • Receptor
    • Search
    • Human
    • Chromosome
    • Location
    • Type
    • Bp
    • Chr
    • Bmp
    • External
  • gene
    • Location
    • Human
    • Morphogenetic
    • Chromosome
    • Protein
    • Bp
    • Chr
    • Receptor
    • Activity
    • End
    • Function
    • Mouse
  • bone morphogenetic protein
    • Morphogenetic
    • Protein
    • Activity
    • Cdw293
    • Differentiation
    • Function
    • Search
    • Receptor
    • Endochondral
    • Gene
    • Human
    • Chromosome
  • function
    • Activity
    • Search
    • Morphogenetic
    • Bmp
    • Chromosome
    • Location
    • Protein
    • Transmembrane
    • Type
    • Bp
    • Chr
    • Receptor

Connections between topic areas Semantic bridges

For BMPR1B, one of the stronger structural bridges in this analysis connects BMPR1B with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BMPR1BOverview · splits 6 ⟂ 4
BMPR1BClinical significance · splits 7 ⟂ 3

Map overview Semantic statistics

BMPR1B

Nodes10
Edges9
Triples142
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around BMPR1B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BMPR1B · EN edition · Analysis: TopicsToTalkAbout

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