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SF3B4: Measurement, Interactions & Function

Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene.

Language: English [EN]
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SF3B4 topic overview

The analysis highlights Measurement, Interactions and Function as prominent areas in the source structure around SF3B4.

Related topics
9
Source areas
4
Connected nodes
13
Extracted relationships
87
Concept neighborhoods
9
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Function · 2 topics
Overview · 2 topics
Disease associations · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SF3B4, AFD1, Hsh49, SAP49, SF3b49, splicing factor 3b subunit 4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X5T, 1X5U
Band
1q21.2 · 3|3 F2.1
Bgee
mucosa of transverse colon · granulocyte · left uterine tube · left testis · right testis
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Disease associations

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SF3B4 connects Entity context

The extracted context around SF3B4 shows recurring relationship patterns in the source. For example, SF3B4 → embryo, epiblast, ganglionic eminence, genital tubercle, granulocyte, left testis, left uterine tube, mesencephalon, monocyte, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, popliteal artery, right coronary artery, right testis, tail of embryo, tibial arteries, ventricular zone, yolk sac Another extracted example is SF3B4 → mRNA processing, mRNA splicing, via spliceosome, nucleic acid binding, nucleolus, nucleoplasm, nucleus, positive regulation of mRNA splicing, via spliceosome, protein binding, ribonucleoprotein complex, RNA binding, RNA splicing, RNA splicing, via transesterification reactions, spliceosomal complex, U12-type spliceosomal complex, U2-type precatalytic spliceosome. Use these groups to spot repeated connection types before inspecting the individual relationships.

SF3B4

Top relations

Bgee · 19
SF3B4 → embryo, epiblast, ganglionic eminence, genital tubercle, granulocyte, left testis, left uterine tube, mesencephalon, monocyte, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, popliteal artery, right coronary artery, right testis, tail of embryo, tibial arteries, ventricular zone, yolk sac
RNA expression pattern · 19
SF3B4 → embryo, epiblast, ganglionic eminence, genital tubercle, granulocyte, left testis, left uterine tube, mesencephalon, monocyte, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, popliteal artery, right coronary artery, right testis, tail of embryo, tibial arteries, ventricular zone, yolk sac
Gene ontology · 15
SF3B4 → mRNA processing, mRNA splicing, via spliceosome, nucleic acid binding, nucleolus, nucleoplasm, nucleus, positive regulation of mRNA splicing, via spliceosome, protein binding, ribonucleoprotein complex, RNA binding, RNA splicing, RNA splicing, via transesterification reactions, spliceosomal complex, U12-type spliceosomal complex, U2-type precatalytic spliceosome
related to Disease associations · 7
SF3B4 → Canadian, Finding, FORGE, GEnes, In, Nager, Rare
related to Interactions · 3
SF3B4 → BMPR1A, CDC5L, SF3B2
Band · 2
SF3B4 → 1q21.2, 3|3 F2.1
Chr. · 2
SF3B4 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
SF3B4 → 149,927,803 bp, 96,084,880 bp
Aliases · 1
SF3B4 → SF3B4, AFD1, Hsh49, SAP49, SF3b49, splicing factor 3b subunit 4
Available structures · 1
SF3B4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X5T, 1X5U

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band splicing protein chromosome factor 3b location subunit mouse ucsc function external encoded search 927 803

SF3B4 relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around SF3B4. Examples in this analysis include SF3B4 → Aliases → SF3B4, AFD1, Hsh49, SAP49, SF3b49, splicing factor 3b subunit 4 and SF3B4 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X5T, 1X5U. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SF3B4AliasesSF3B4, AFD1, Hsh49, SAP49, SF3b49, splicing factor 3b subunit 41.00infobox
SF3B4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X5T, 1X5U1.00infobox
SF3B4Band1q21.21.00infobox
SF3B4Band3|3 F2.11.00infobox
SF3B4Bgeemucosa of transverse colon1.00infobox
SF3B4Bgeegranulocyte1.00infobox
SF3B4Bgeeleft uterine tube1.00infobox
SF3B4Bgeeleft testis1.00infobox
SF3B4Bgeeright testis1.00infobox
SF3B4Bgeepopliteal artery1.00infobox
SF3B4Bgeetibial arteries1.00infobox
SF3B4Bgeemonocyte1.00infobox
SF3B4Bgeeright coronary artery1.00infobox
SF3B4Bgeeolfactory zone of nasal mucosa1.00infobox
SF3B4Bgeetail of embryo1.00infobox
SF3B4Bgeegenital tubercle1.00infobox
SF3B4Bgeeepiblast1.00infobox
SF3B4Bgeeneural tube1.00infobox
SF3B4Bgeeembryo1.00infobox
SF3B4Bgeemesencephalon1.00infobox
SF3B4Bgeeyolk sac1.00infobox
SF3B4Bgeeventricular zone1.00infobox
SF3B4Bgeeganglionic eminence1.00infobox
SF3B4BioGPSMore reference expression data1.00infobox
SF3B4Chr.Chromosome 1 (human)1.00infobox
SF3B4Chr.Chromosome 3 (mouse)1.00infobox
SF3B4DatabasesNCBI: entry; OMA: entry1.00infobox
SF3B4End149,927,803 bp1.00infobox
SF3B4End96,084,880 bp1.00infobox
SF3B4EnsemblENSG000001433681.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SF3B4 bring nearby vocabulary together. In this analysis, examples include Gene, Human and Ucsc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SF3B4
    • Gene
    • Human
    • Ucsc
    • Location
    • Splicing
    • Browser
    • Disease
    • Function
    • Genome
    • Search
    • Subunit
    • Chromosome
  • sf3b4
    • Gene
    • Human
    • Ucsc
    • Location
    • Splicing
    • Browser
    • Disease
    • Function
    • Genome
    • Search
    • Subunit
    • Chromosome
  • gene
    • Human
    • Location
    • Sf3b4
    • Ucsc
    • Chromosome
    • Splicing
    • Bp
    • Chr
    • Protein
    • Browser
    • Complex
    • End
  • splicing factor 3b
    • 3b
    • Factor
    • Splicing
    • Subunit
    • Function
    • Protein
    • Search
    • Gene
    • Sf3b4
    • Chromosome
    • Location
    • Bp
  • function
    • Search
    • Chromosome
    • External
    • Interactions
    • Links
    • Location
    • Reading
    • References
    • Splicing
    • Bp
    • Chr
    • Complex
  • protein
    • Splicing
    • Complex
    • Directly
    • Encoded
    • Pre-mrna
    • Gene
    • Subunit
    • Humans
    • Sf3b4
    • End
    • F2
    • Function
  • disease associations
    • External
    • Interactions
    • Links
    • Reading
    • References
    • Associations
    • Disease
    • Function
    • Search
    • Subunit
    • Sf3b4
    • Chromosome
  • interactions
    • Links
    • Reading
    • References
    • Search
    • Subunit
    • Location
    • Splicing
    • Human
    • Sf3b4

Connections between topic areas Semantic bridges

For SF3B4, one of the stronger structural bridges in this analysis connects SF3B4 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SF3B4Interactions · splits 9 ⟂ 5
SF3B4Overview · splits 11 ⟂ 3
SF3B4Function · splits 11 ⟂ 3

Map overview Semantic statistics

SF3B4

Nodes14
Edges13
Triples87
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around SF3B4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SF3B4 · EN edition · Analysis: TopicsToTalkAbout

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