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Vitamin C: History, Research & Products

Vitamin C or ascorbate is a water-soluble vitamin found in citrus and other fruits, berries and vegetables. It is found as a form of ascorbic acid. It is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters. It is required for the functioning of several enzymes and is…

Language: English [EN]
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Vitamin C topic overview

The analysis highlights History, Research and Products as prominent areas in the source structure around Vitamin C.

Related topics
251
Source areas
11
Connected nodes
269
Extracted relationships
329
Concept neighborhoods
45
Bridge connections
269

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 58 topics
History · 47 topics
Pharmacology · 42 topics
Health effects · 31 topics
Synthesis · 30 topics
Food preservation additive · 12 topics
Chemistry · 11 topics
Diet · 7 topics
Adverse effects · 5 topics
Deficiency · 4 topics
Research directions · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A11GA01 (WHO) A11GB01 (WHO) G01AD03 (WHO) S01XA15 (WHO)
Bioavailability
Rapid, diminishes as dose increases
Boiling point
552.7 °C (1,026.9 °F)
CAS Number
50-81-7 Y · as salt: 134-03-2 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Chemistry

Deficiency

Diet

Sources

Food preservation additive

Pharmacology

Synthesis

Health effects

Adverse effects

History

Research directions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Vitamin C connects Entity context

The extracted context around Vitamin C shows recurring relationship patterns in the source. For example, Vitamin C → ADP, C1, C4, FAD, Gulonolactone, Haplorrhini, L-gulonolactone, NAD, NADPH, One, Recent, Reptiles, The, There, This, UDP-glucose, UDP-glucuronate, UDP-glucuronic, UMP, Unitary Another extracted example is Vitamin C → Active, Approximately, Ascorbic, DHA, For, GLUT1, GLUT3, GLUT4, GLUTs, Hexose Transporter, However, In, Sodium-Ascorbate Co-Transporter, SVCT1, SVCT2, SVCTs, The, The Hexose Transporter. Use these groups to spot repeated connection types before inspecting the individual relationships.

Vitamin C

Top relations

related to Animal synthesis · 20
Vitamin C → ADP, C1, C4, FAD, Gulonolactone, Haplorrhini, L-gulonolactone, NAD, NADPH, One, Recent, Reptiles, The, There, This, UDP-glucose, UDP-glucuronate, UDP-glucuronic, UMP, Unitary
related to Pharmacokinetics · 18
Vitamin C → Active, Approximately, Ascorbic, DHA, For, GLUT1, GLUT3, GLUT4, GLUTs, Hexose Transporter, However, In, Sodium-Ascorbate Co-Transporter, SVCT1, SVCT2, SVCTs, The, The Hexose Transporter
related to Food fortification · 17
Vitamin C → As, Bureau, Countries, Food, Food Aid Commodities, Fortification, Humanitarian Assistance, Its, L-ascorbic, Oxidative, Peace Act, Supplemental, The, To, United States, Vitamin, While
related to Scurvy · 17
Vitamin C → As, Britain, British, C-containing, C-free, Early, In, Iowa, Men, Notable, Scurvy, The, These, Treatment, Until, Without, World War II
related to Discovery · 16
Vitamin C → Axel Holst, Casimir Funk, Hoffmann, In, La Roche, Norwegian, One, Polish, Redoxon, Reichstein, Shortly, Tadeus Reichstein, Theodor Frølich, This, Unknown, Vitamin
related to Industrial synthesis · 15
Vitamin C → Both, China, Cost, European Union, Hamburg, India, KGA, North America, Reichstein, Researchers, Shanghai, The, The Reichstein, US, Vitamin
has effect · 14
Vitamin C → Beyond, Essential Medicines, Forumulary, However, In, It, More, No, Oral, These, United States, Vitamin, World Health Organization's List, World Health Organization's Model
related to COVID-19 · 14
Vitamin C → COVID-19, COVID-19 Treatment Guidelines, COVID-19 Treatment Guidelines Panel, December, From March, Health, In, In April, July, NIH, Panel, There, US FDA, US National Institutes
related to Food labeling · 14
Vitamin C → Daily Value, Daily Values, DV, European Union, For, For US, Instead, May, RDA, Reference Daily Intake, Reference Intakes, RI, RIs, Voluntary
related to history · 13
Vitamin C → An, As, Briefly, HIV, Irwin Stone, Linus Pauling, Matthias Rath, Mega-dosing, Patrick Holford, Pauling, Pauling's, The, Vitamin

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vitamin acid ascorbic scurvy mg also dietary may intake synthesize ascorbate deficiency food day higher disease enzyme concentrations people high

Vitamin C relationships Subject–Predicate–Object triples

TTTA extracted 329 structured relationships around Vitamin C. Examples in this analysis include Vitamin C → 3D model (JSmol) → Interactive image and Vitamin C → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Vitamin C3D model (JSmol)Interactive image1.00infobox
Vitamin CAHFS/Drugs.comMonograph1.00infobox
Vitamin CATC codeA11GA01 (WHO) A11GB01 (WHO) G01AD03 (WHO) S01XA15 (WHO)1.00infobox
Vitamin CBioavailabilityRapid, diminishes as dose increases1.00infobox
Vitamin CBoiling point552.7 °C (1,026.9 °F)1.00infobox
Vitamin CCAS Number50-81-7 Y1.00infobox
Vitamin CCAS Numberas salt: 134-03-2 Y1.00infobox
Vitamin CChEBICHEBI:29073 Y1.00infobox
Vitamin CChEBIas salt: CHEBI:113451 Y1.00infobox
Vitamin CChEMBLChEMBL196 Y1.00infobox
Vitamin CChEMBLas salt: ChEMBL591665 Y1.00infobox
Vitamin CChemSpider10189562 Y1.00infobox
Vitamin CChemSpideras salt: 16736174 Y1.00infobox
Vitamin CCompTox Dashboard (EPA)DTXSID50201061.00infobox
Vitamin CDensity1.694 g/cm31.00infobox
Vitamin CDrugBankDB00126 Y1.00infobox
Vitamin CDrugBankas salt: DB14482 Y1.00infobox
Vitamin CE numberE300 (antioxidants, ...)1.00infobox
Vitamin CECHA InfoCard100.000.0611.00infobox
Vitamin CElimination half-lifeVaries according to plasma concentration1.00infobox
Vitamin CExcretionKidney1.00infobox
Vitamin CFormulaC6H8O61.00infobox
Vitamin CIUPHAR/BPS47811.00infobox
Vitamin CKEGGD00018 Y1.00infobox
Vitamin CKEGGas salt: D05853 Y1.00infobox
Vitamin CLegal statusAU: Unscheduled1.00infobox
Vitamin CLegal statusUK: POM (Prescription only) / GSL1.00infobox
Vitamin CLegal statusUS: ℞-only / OTC/ Dietary Supplement1.00infobox
Vitamin CLicense dataUS DailyMed: Ascorbic acid1.00infobox
Vitamin CMedlinePlusa6825831.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Vitamin C bring nearby vocabulary together. In this analysis, examples include Dietary, Food and Synthesize. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Vitamin C
    • Dietary
    • Food
    • Synthesize
    • Intake
    • People
    • Treatment
    • May
    • Mg
    • Deficiency
    • Intravenous
    • Supplementation
    • Higher
  • vitamin c
    • Dietary
    • Food
    • Synthesize
    • Intake
    • People
    • Treatment
    • May
    • Mg
    • Deficiency
    • Intravenous
    • Supplementation
    • Higher
  • vitamin
    • Dietary
    • Food
    • Synthesize
    • Intake
    • People
    • Treatment
    • May
    • Mg
    • Deficiency
    • Intravenous
    • Supplementation
    • Higher
  • ascorbic acid
    • Acid
    • Ascorbic
    • Ascorbate
    • Enzyme
    • Found
    • Intake
    • Synthesis
    • High
    • Concentrations
    • Cancer
    • Cofactor
    • Food
  • synthesize their own vitamin c
    • Dietary
    • Food
    • Synthesize
    • Vitamin
    • Intake
    • People
    • Treatment
    • May
    • Mg
    • Deficiency
    • Also
    • Intravenous
  • dietary supplement
    • Supplement
    • Intake
    • Recommended
    • Food
    • Higher
    • Vitamin
    • Low
    • Mg
    • Scurvy
    • Health
    • Humans
    • Supplementation
  • recommended dietary intake
    • Supplement
    • Intake
    • Recommended
    • Food
    • Higher
    • Mg
    • Vitamin
    • Low
    • Supplementation
    • Plasma
    • Concentrations
    • Day
  • uric acid
    • Ascorbic
    • Ascorbate
    • Enzyme
    • Synthesis
    • Intake
    • Found
    • Cofactor
    • High
    • Concentrations
    • May
    • Scurvy
    • Vitamin

Connections between topic areas Semantic bridges

For Vitamin C, one of the stronger structural bridges in this analysis connects Vitamin C with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Vitamin COverview · splits 211 ⟂ 59
Vitamin CHistory · splits 222 ⟂ 48
Vitamin CPharmacology · splits 227 ⟂ 43
Vitamin CHealth effects · splits 238 ⟂ 32
Vitamin CSynthesis · splits 239 ⟂ 31
Vitamin CFood preservation additive · splits 257 ⟂ 13
Vitamin CChemistry · splits 258 ⟂ 12
Vitamin CDiet · splits 262 ⟂ 8
Vitamin CSources · splits 263 ⟂ 7
Vitamin CAdverse effects · splits 264 ⟂ 6
Vitamin CDeficiency · splits 265 ⟂ 5
Vitamin CResearch directions · splits 265 ⟂ 5

Map overview Semantic statistics

Vitamin C

Nodes270
Edges269
Triples329
Avg. degree1.99
Density0.007407
Components1

Source & methodology

TTTA analyzes the structure around Vitamin C to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Research & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Vitamin C · EN edition · Analysis: TopicsToTalkAbout

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