EGLN2

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Overview

Protein Gene Alpha-ketoglutarate-dependent hydroxylase Hypoxia inducible factor Oxygen homeostasis

6 related topics

Key facts & relationships

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1.14.11.29: ↗
Aliases: EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6
Band: 19q13.2 · 7 A3|7 15.83 cM
Bgee: left testis · right testis · blood · spleen · right lung
BioGPS: More reference expression data
Chr.: Chromosome 19 (human) · Chromosome 7 (mouse)

Topics to explore

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Overview

Protein
Gene
Alpha-ketoglutarate-dependent hydroxylase
Hypoxia inducible factor
Oxygen homeostasis Oxygen homeostasis?action=edit&redlink=1
Prolyl hydroxylation Prolyl hydroxylase

Advanced semantic analysis

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Map overview Semantic statistics

Nodes8

Edges7

Triples83

Avg. degree1.75

Density0.25

Components1

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EGLN2

Top relations

Gene ontology · 21

EGLN2 → 2-oxoglutarate-dependent dioxygenase activity, cell redox homeostasis, dioxygenase activity, ferrous iron binding, intracellular estrogen receptor signaling pathway, iron ion binding, L-ascorbic acid binding, metal ion binding, nucleoplasm, nucleus, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen gasoreceptor activity, peptidyl-proline 4-dioxygenase activity, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, positive regulation of protein catabolic process, protein binding, regulation of cell growth, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia

Bgee · 20

EGLN2 → apex of heart, blood, CA3 field, choroid plexus of fourth ventricle, crypt of lieberkuhn of small intestine, entorhinal cortex, Ileal epithelium, left testis, mucosa of transverse colon, muscle of thigh, Paneth cell, perirhinal cortex, primary visual cortex, putamen, right lung, right testis, seminiferous tubule, spermatid, spleen, upper lobe of left lung

RNA expression pattern · 20

Band · 2

EGLN2 → 19q13.2, 7 A3|7 15.83 cM

Chr. · 2

EGLN2 → Chromosome 19 (human), Chromosome 7 (mouse)

End · 2

EGLN2 → 26,866,227 bp, 40,808,434 bp

1.14.11.29 · 1

EGLN2 → ↗

Aliases · 1

EGLN2 → EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6

BioGPS · 1

EGLN2 → More reference expression data

Databases · 1

EGLN2 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

gene bp chr human band protein chromosome 19 oxygen hypoxia location hif mouse inducible factor homeostasis hydroxylation enzyme activity 808

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
EGLN2	1.14.11.29	↗	1.00	infobox
EGLN2	Aliases	EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6	1.00	infobox
EGLN2	Band	19q13.2	1.00	infobox
EGLN2	Band	7 A3\|7 15.83 cM	1.00	infobox
EGLN2	Bgee	left testis	1.00	infobox
EGLN2	Bgee	right testis	1.00	infobox
EGLN2	Bgee	blood	1.00	infobox
EGLN2	Bgee	spleen	1.00	infobox
EGLN2	Bgee	right lung	1.00	infobox
EGLN2	Bgee	apex of heart	1.00	infobox
EGLN2	Bgee	upper lobe of left lung	1.00	infobox
EGLN2	Bgee	mucosa of transverse colon	1.00	infobox
EGLN2	Bgee	primary visual cortex	1.00	infobox
EGLN2	Bgee	putamen	1.00	infobox
EGLN2	Bgee	seminiferous tubule	1.00	infobox
EGLN2	Bgee	entorhinal cortex	1.00	infobox
EGLN2	Bgee	Ileal epithelium	1.00	infobox
EGLN2	Bgee	perirhinal cortex	1.00	infobox
EGLN2	Bgee	choroid plexus of fourth ventricle	1.00	infobox
EGLN2	Bgee	CA3 field	1.00	infobox
EGLN2	Bgee	spermatid	1.00	infobox
EGLN2	Bgee	muscle of thigh	1.00	infobox
EGLN2	Bgee	Paneth cell	1.00	infobox
EGLN2	Bgee	crypt of lieberkuhn of small intestine	1.00	infobox
EGLN2	BioGPS	More reference expression data	1.00	infobox
EGLN2	Chr.	Chromosome 19 (human)	1.00	infobox
EGLN2	Chr.	Chromosome 7 (mouse)	1.00	infobox
EGLN2	Databases	NCBI: entry; OMA: entry	1.00	infobox
EGLN2	End	40,808,434 bp	1.00	infobox
EGLN2	End	26,866,227 bp	1.00	infobox

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