Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

EGLN2: Overview, Related Topics & Entities

Egl nine homolog 2 is a protein that in humans is encoded by the EGLN2 gene. ELGN2 is an alpha-ketoglutarate-dependent hydroxylase, a superfamily of non-haem iron-containing proteins.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

EGLN2 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around EGLN2.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
83
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.11.29
Aliases
EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6
Band
19q13.2 · 7 A3|7 15.83 cM
Bgee
left testis · right testis · blood · spleen · right lung
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EGLN2 connects Entity context

The extracted context around EGLN2 shows recurring relationship patterns in the source. For example, EGLN2 → 2-oxoglutarate-dependent dioxygenase activity, cell redox homeostasis, dioxygenase activity, ferrous iron binding, intracellular estrogen receptor signaling pathway, iron ion binding, L-ascorbic acid binding, metal ion binding, nucleoplasm, nucleus, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen gasoreceptor activity, peptidyl-proline 4-dioxygenase activity, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, positive regulation of protein catabolic process, protein binding, regulation of cell growth, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia Another extracted example is EGLN2 → apex of heart, blood, CA3 field, choroid plexus of fourth ventricle, crypt of lieberkuhn of small intestine, entorhinal cortex, Ileal epithelium, left testis, mucosa of transverse colon, muscle of thigh, Paneth cell, perirhinal cortex, primary visual cortex, putamen, right lung, right testis, seminiferous tubule, spermatid, spleen, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.

EGLN2

Top relations

Gene ontology · 21
EGLN2 → 2-oxoglutarate-dependent dioxygenase activity, cell redox homeostasis, dioxygenase activity, ferrous iron binding, intracellular estrogen receptor signaling pathway, iron ion binding, L-ascorbic acid binding, metal ion binding, nucleoplasm, nucleus, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen gasoreceptor activity, peptidyl-proline 4-dioxygenase activity, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, positive regulation of protein catabolic process, protein binding, regulation of cell growth, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia
Bgee · 20
EGLN2 → apex of heart, blood, CA3 field, choroid plexus of fourth ventricle, crypt of lieberkuhn of small intestine, entorhinal cortex, Ileal epithelium, left testis, mucosa of transverse colon, muscle of thigh, Paneth cell, perirhinal cortex, primary visual cortex, putamen, right lung, right testis, seminiferous tubule, spermatid, spleen, upper lobe of left lung
RNA expression pattern · 20
EGLN2 → apex of heart, blood, CA3 field, choroid plexus of fourth ventricle, crypt of lieberkuhn of small intestine, entorhinal cortex, Ileal epithelium, left testis, mucosa of transverse colon, muscle of thigh, Paneth cell, perirhinal cortex, primary visual cortex, putamen, right lung, right testis, seminiferous tubule, spermatid, spleen, upper lobe of left lung
Band · 2
EGLN2 → 19q13.2, 7 A3|7 15.83 cM
Chr. · 2
EGLN2 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
EGLN2 → 26,866,227 bp, 40,808,434 bp
1.14.11.29 · 1
EGLN2 → ↗
Aliases · 1
EGLN2 → EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6
BioGPS · 1
EGLN2 → More reference expression data
Databases · 1
EGLN2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band protein chromosome 19 oxygen hypoxia location hif mouse inducible factor homeostasis hydroxylation enzyme activity 808

EGLN2 relationships Subject–Predicate–Object triples

TTTA extracted 83 structured relationships around EGLN2. Examples in this analysis include EGLN2 → 1.14.11.29 → ↗ and EGLN2 → Aliases → EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EGLN21.14.11.291.00infobox
EGLN2AliasesEGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-61.00infobox
EGLN2Band19q13.21.00infobox
EGLN2Band7 A3|7 15.83 cM1.00infobox
EGLN2Bgeeleft testis1.00infobox
EGLN2Bgeeright testis1.00infobox
EGLN2Bgeeblood1.00infobox
EGLN2Bgeespleen1.00infobox
EGLN2Bgeeright lung1.00infobox
EGLN2Bgeeapex of heart1.00infobox
EGLN2Bgeeupper lobe of left lung1.00infobox
EGLN2Bgeemucosa of transverse colon1.00infobox
EGLN2Bgeeprimary visual cortex1.00infobox
EGLN2Bgeeputamen1.00infobox
EGLN2Bgeeseminiferous tubule1.00infobox
EGLN2Bgeeentorhinal cortex1.00infobox
EGLN2BgeeIleal epithelium1.00infobox
EGLN2Bgeeperirhinal cortex1.00infobox
EGLN2Bgeechoroid plexus of fourth ventricle1.00infobox
EGLN2BgeeCA3 field1.00infobox
EGLN2Bgeespermatid1.00infobox
EGLN2Bgeemuscle of thigh1.00infobox
EGLN2BgeePaneth cell1.00infobox
EGLN2Bgeecrypt of lieberkuhn of small intestine1.00infobox
EGLN2BioGPSMore reference expression data1.00infobox
EGLN2Chr.Chromosome 19 (human)1.00infobox
EGLN2Chr.Chromosome 7 (mouse)1.00infobox
EGLN2DatabasesNCBI: entry; OMA: entry1.00infobox
EGLN2End40,808,434 bp1.00infobox
EGLN2End26,866,227 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around EGLN2 bring nearby vocabulary together. In this analysis, examples include Activity, Gene and Hypoxia. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • EGLN2
    • Activity
    • Gene
    • Hypoxia
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Homolog
    • Humans
  • egln2
    • Activity
    • Gene
    • Hypoxia
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Homolog
    • Humans
  • protein
    • Egln2
    • Egl
    • Encoded
    • Gene
    • Homolog
    • Humans
    • Nine
    • A3
    • Activity
    • End
    • Homeostasis
    • Hydroxylation
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • A3
    • Activity
    • End
    • Enzyme
    • Mouse
    • Hypoxia
    • Protein
  • hypoxia inducible factor
    • Inducible
    • Activity
    • Factor
    • Homeostasis
    • Hypoxia
    • Location
    • Oxygen
    • Chromosome
    • Human
    • Bp
    • Chr
    • Enzyme
  • oxygen homeostasis
    • Hypoxia
    • Oxygen
    • A3
    • Activity
    • End
    • Hydroxylation
    • Inducible
    • Mouse
    • Location
    • Protein
    • Band
    • Chromosome
  • prolyl hydroxylation
    • Oxygen
    • A3
    • Activity
    • End
    • Mouse
    • Hypoxia
    • Location
    • Protein
    • Band
    • Chromosome
    • Human
    • Bp
  • alpha-ketoglutarate-dependent hydroxylase
    • Elgn2
    • Hydroxylase
    • Iron-containing
    • Non-haem
    • Superfamily

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the EGLN2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

EGLN2

Nodes8
Edges7
Triples83
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around EGLN2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EGLN2 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.