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Egl nine homolog 3 is a protein that in humans is encoded by the EGLN3 gene. ELGN3 is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases, which are non-haem iron-containing proteins.
The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around EGLN3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around EGLN3 shows recurring relationship patterns in the source. For example, EGLN3 → 2-oxoglutarate-dependent dioxygenase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to DNA damage stimulus, cytoplasm, cytosol, dioxygenase activity, iron ion binding, L-ascorbic acid binding, metal ion binding, nucleoplasm, nucleus, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, peptidyl-proline 4-dioxygenase activity, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, protein binding, protein hydroxylation, regulation of cell population proliferation, regulation of neuron apoptotic process Another extracted example is EGLN3 → amygdala, apex of heart, C1 segment, conjunctival fornix, digastric muscle, epithelium of small intestine, epithelium of stomach, esophagus, left ventricle, masseter muscle, mucous cell of stomach, pyloric antrum, rectum, right auricle of heart, right uterine tube, skin of abdomen, skin of leg, sternocleidomastoid muscle, temporal muscle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp chr human band gene 14 chromosome location protein mouse hypoxia activity 462 774 end 34 12 250 646 egl
TTTA extracted 84 structured relationships around EGLN3. Examples in this analysis include EGLN3 → 1.14.11.29 → ↗ and EGLN3 → Aliases → EGLN3, HIFP4H3, HIFPH3, PHD3, egl-9 family hypoxia inducible factor 3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| EGLN3 | 1.14.11.29 | ↗ | 1.00 | infobox |
| EGLN3 | Aliases | EGLN3, HIFP4H3, HIFPH3, PHD3, egl-9 family hypoxia inducible factor 3 | 1.00 | infobox |
| EGLN3 | Band | 14q13.1 | 1.00 | infobox |
| EGLN3 | Band | 12|12 C1 | 1.00 | infobox |
| EGLN3 | Bgee | skin of leg | 1.00 | infobox |
| EGLN3 | Bgee | skin of abdomen | 1.00 | infobox |
| EGLN3 | Bgee | apex of heart | 1.00 | infobox |
| EGLN3 | Bgee | left ventricle | 1.00 | infobox |
| EGLN3 | Bgee | right auricle of heart | 1.00 | infobox |
| EGLN3 | Bgee | ventricular zone | 1.00 | infobox |
| EGLN3 | Bgee | right uterine tube | 1.00 | infobox |
| EGLN3 | Bgee | rectum | 1.00 | infobox |
| EGLN3 | Bgee | C1 segment | 1.00 | infobox |
| EGLN3 | Bgee | amygdala | 1.00 | infobox |
| EGLN3 | Bgee | temporal muscle | 1.00 | infobox |
| EGLN3 | Bgee | masseter muscle | 1.00 | infobox |
| EGLN3 | Bgee | esophagus | 1.00 | infobox |
| EGLN3 | Bgee | mucous cell of stomach | 1.00 | infobox |
| EGLN3 | Bgee | conjunctival fornix | 1.00 | infobox |
| EGLN3 | Bgee | digastric muscle | 1.00 | infobox |
| EGLN3 | Bgee | epithelium of small intestine | 1.00 | infobox |
| EGLN3 | Bgee | epithelium of stomach | 1.00 | infobox |
| EGLN3 | Bgee | pyloric antrum | 1.00 | infobox |
| EGLN3 | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| EGLN3 | BioGPS | More reference expression data | 1.00 | infobox |
| EGLN3 | Chr. | Chromosome 14 (human) | 1.00 | infobox |
| EGLN3 | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| EGLN3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| EGLN3 | End | 34,462,774 bp | 1.00 | infobox |
| EGLN3 | End | 54,250,646 bp | 1.00 | infobox |
The concept neighborhoods around EGLN3 bring nearby vocabulary together. In this analysis, examples include Gene, Activity and Hypoxia. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the EGLN3 map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around EGLN3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — EGLN3 · EN edition · Analysis: TopicsToTalkAbout