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EGLN3

Egl nine homolog 3 is a protein that in humans is encoded by the EGLN3 gene. ELGN3 is a member of the superfamily of alpha-ketoglutarate-dependent hydroxylases, which are non-haem iron-containing proteins.

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1.14.11.29
Aliases
EGLN3, HIFP4H3, HIFPH3, PHD3, egl-9 family hypoxia inducible factor 3
Band
14q13.1 · 12|12 C1
Bgee
skin of leg · skin of abdomen · apex of heart · left ventricle · right auricle of heart
BioGPS
More reference expression data
Chr.
Chromosome 14 (human) · Chromosome 12 (mouse)

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EGLN3

Nodes5
Edges4
Triples84
Avg. degree1.6
Density0.4
Components1

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EGLN3

Top relations

Gene ontology · 22
EGLN3 → 2-oxoglutarate-dependent dioxygenase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to DNA damage stimulus, cytoplasm, cytosol, dioxygenase activity, iron ion binding, L-ascorbic acid binding, metal ion binding, nucleoplasm, nucleus, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, peptidyl-proline 4-dioxygenase activity, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, protein binding, protein hydroxylation, regulation of cell population proliferation, regulation of neuron apoptotic process
Bgee · 20
EGLN3 → amygdala, apex of heart, C1 segment, conjunctival fornix, digastric muscle, epithelium of small intestine, epithelium of stomach, esophagus, left ventricle, masseter muscle, mucous cell of stomach, pyloric antrum, rectum, right auricle of heart, right uterine tube, skin of abdomen, skin of leg, sternocleidomastoid muscle, temporal muscle, ventricular zone
RNA expression pattern · 20
EGLN3 → amygdala, apex of heart, C1 segment, conjunctival fornix, digastric muscle, epithelium of small intestine, epithelium of stomach, esophagus, left ventricle, masseter muscle, mucous cell of stomach, pyloric antrum, rectum, right auricle of heart, right uterine tube, skin of abdomen, skin of leg, sternocleidomastoid muscle, temporal muscle, ventricular zone
Band · 2
EGLN3 → 12|12 C1, 14q13.1
Chr. · 2
EGLN3 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
EGLN3 → 34,462,774 bp, 54,250,646 bp
1.14.11.29 · 1
EGLN3 → ↗
Aliases · 1
EGLN3 → EGLN3, HIFP4H3, HIFPH3, PHD3, egl-9 family hypoxia inducible factor 3
BioGPS · 1
EGLN3 → More reference expression data
Databases · 1
EGLN3 → NCBI: entry; OMA: entry

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Important terminology

bp chr human band gene 14 chromosome location protein mouse hypoxia activity 462 774 end 34 12 250 646 egl

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EGLN31.14.11.291.00infobox
EGLN3AliasesEGLN3, HIFP4H3, HIFPH3, PHD3, egl-9 family hypoxia inducible factor 31.00infobox
EGLN3Band14q13.11.00infobox
EGLN3Band12|12 C11.00infobox
EGLN3Bgeeskin of leg1.00infobox
EGLN3Bgeeskin of abdomen1.00infobox
EGLN3Bgeeapex of heart1.00infobox
EGLN3Bgeeleft ventricle1.00infobox
EGLN3Bgeeright auricle of heart1.00infobox
EGLN3Bgeeventricular zone1.00infobox
EGLN3Bgeeright uterine tube1.00infobox
EGLN3Bgeerectum1.00infobox
EGLN3BgeeC1 segment1.00infobox
EGLN3Bgeeamygdala1.00infobox
EGLN3Bgeetemporal muscle1.00infobox
EGLN3Bgeemasseter muscle1.00infobox
EGLN3Bgeeesophagus1.00infobox
EGLN3Bgeemucous cell of stomach1.00infobox
EGLN3Bgeeconjunctival fornix1.00infobox
EGLN3Bgeedigastric muscle1.00infobox
EGLN3Bgeeepithelium of small intestine1.00infobox
EGLN3Bgeeepithelium of stomach1.00infobox
EGLN3Bgeepyloric antrum1.00infobox
EGLN3Bgeesternocleidomastoid muscle1.00infobox
EGLN3BioGPSMore reference expression data1.00infobox
EGLN3Chr.Chromosome 14 (human)1.00infobox
EGLN3Chr.Chromosome 12 (mouse)1.00infobox
EGLN3DatabasesNCBI: entry; OMA: entry1.00infobox
EGLN3End34,462,774 bp1.00infobox
EGLN3End54,250,646 bp1.00infobox

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