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P4HA1: Measurement & Overview

Prolyl 4-hydroxylase subunit alpha-1 is an enzyme that in humans is encoded by the P4HA1 gene.

Language: English [EN]
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P4HA1 topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around P4HA1.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
83
Concept neighborhoods
9
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.11.2
Aliases
P4HA1, P4HA, prolyl 4-hydroxylase subunit alpha 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TJC, 2V5F, 2YQ8, 4BT8, 4BT9, 4BTA, 4BTB
Band
10q22.1 · 10|10 B4
Bgee
cartilage tissue · Achilles tendon · tibia · ventricular zone · pericardium
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How P4HA1 connects Entity context

The extracted context around P4HA1 shows recurring relationship patterns in the source. For example, P4HA1 → Achilles tendon, body of femur, calvaria, cartilage tissue, cumulus cell, dermis, epithelium of lens, gastrocnemius muscle, pericardium, periodontal fiber, right lung lobe, sciatic nerve, stroma of bone marrow, stromal cell of endometrium, tibia, tibialis anterior muscle, triceps brachii muscle, umbilical cord, ventricular zone, yolk sac Another extracted example is P4HA1 → collagen fibril organization, dioxygenase activity, endoplasmic reticulum, endoplasmic reticulum lumen, identical protein binding, intracellular membrane-bounded organelle, iron ion binding, L-ascorbic acid binding, membrane, metal ion binding, mitochondrion, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, procollagen-proline 4-dioxygenase activity, procollagen-proline 4-dioxygenase complex, protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

P4HA1

Top relations

Bgee · 20
P4HA1 → Achilles tendon, body of femur, calvaria, cartilage tissue, cumulus cell, dermis, epithelium of lens, gastrocnemius muscle, pericardium, periodontal fiber, right lung lobe, sciatic nerve, stroma of bone marrow, stromal cell of endometrium, tibia, tibialis anterior muscle, triceps brachii muscle, umbilical cord, ventricular zone, yolk sac
RNA expression pattern · 20
P4HA1 → Achilles tendon, body of femur, calvaria, cartilage tissue, cumulus cell, dermis, epithelium of lens, gastrocnemius muscle, pericardium, periodontal fiber, right lung lobe, sciatic nerve, stroma of bone marrow, stromal cell of endometrium, tibia, tibialis anterior muscle, triceps brachii muscle, umbilical cord, ventricular zone, yolk sac
Gene ontology · 18
P4HA1 → collagen fibril organization, dioxygenase activity, endoplasmic reticulum, endoplasmic reticulum lumen, identical protein binding, intracellular membrane-bounded organelle, iron ion binding, L-ascorbic acid binding, membrane, metal ion binding, mitochondrion, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, procollagen-proline 4-dioxygenase activity, procollagen-proline 4-dioxygenase complex, protein binding
Band · 2
P4HA1 → 10q22.1, 10|10 B4
Chr. · 2
P4HA1 → Chromosome 10 (human), Chromosome 10 (mouse)
End · 2
P4HA1 → 59,209,126 bp, 73,096,974 bp
1.14.11.2 · 1
P4HA1 → ↗
Aliases · 1
P4HA1 → P4HA1, P4HA, prolyl 4-hydroxylase subunit alpha 1
Available structures · 1
P4HA1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TJC, 2V5F, 2YQ8, 4BT8, 4BT9, 4BTA, 4BTB
BioGPS · 1
P4HA1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp enzyme chr prolyl 4-hydroxylase human band collagen chromosome 10 alpha location encoded subunits different mouse subunit component two

P4HA1 relationships Subject–Predicate–Object triples

TTTA extracted 83 structured relationships around P4HA1. Examples in this analysis include P4HA1 → 1.14.11.2 → ↗ and P4HA1 → Aliases → P4HA1, P4HA, prolyl 4-hydroxylase subunit alpha 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
P4HA11.14.11.21.00infobox
P4HA1AliasesP4HA1, P4HA, prolyl 4-hydroxylase subunit alpha 11.00infobox
P4HA1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1TJC, 2V5F, 2YQ8, 4BT8, 4BT9, 4BTA, 4BTB1.00infobox
P4HA1Band10q22.11.00infobox
P4HA1Band10|10 B41.00infobox
P4HA1Bgeecartilage tissue1.00infobox
P4HA1BgeeAchilles tendon1.00infobox
P4HA1Bgeetibia1.00infobox
P4HA1Bgeeventricular zone1.00infobox
P4HA1Bgeepericardium1.00infobox
P4HA1Bgeestromal cell of endometrium1.00infobox
P4HA1Bgeeperiodontal fiber1.00infobox
P4HA1Bgeegastrocnemius muscle1.00infobox
P4HA1Bgeetibialis anterior muscle1.00infobox
P4HA1Bgeetriceps brachii muscle1.00infobox
P4HA1Bgeecalvaria1.00infobox
P4HA1Bgeeepithelium of lens1.00infobox
P4HA1Bgeestroma of bone marrow1.00infobox
P4HA1Bgeeright lung lobe1.00infobox
P4HA1Bgeedermis1.00infobox
P4HA1Bgeebody of femur1.00infobox
P4HA1Bgeecumulus cell1.00infobox
P4HA1Bgeesciatic nerve1.00infobox
P4HA1Bgeeyolk sac1.00infobox
P4HA1Bgeeumbilical cord1.00infobox
P4HA1BioGPSMore reference expression data1.00infobox
P4HA1Chr.Chromosome 10 (human)1.00infobox
P4HA1Chr.Chromosome 10 (mouse)1.00infobox
P4HA1DatabasesNCBI: entry; OMA: entry1.00infobox
P4HA1End73,096,974 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around P4HA1 bring nearby vocabulary together. In this analysis, examples include Activity, Search and Subunit. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Alpha
    • Prolyl
    • Encoded
    • Gene
    • Subunit
    • Subunits
    • P4ha1
    • Composed
    • Encodes
    • Humans
    • Key
    • Synthesis
  • gene
    • Location
    • P4ha1
    • Chromosome
    • Human
    • Prolyl
    • Bp
    • Chr
    • Activity
    • Component
    • End
    • Identical
    • Mouse
  • prolyl 4-hydroxylase
    • Prolyl
    • Enzyme
    • Gene
    • Subunit
    • Alpha
    • Collagen
    • P4ha1
    • 4-hydroxyproline
    • Alpha-1
    • Composed
    • Encodes
    • Humans
  • collagen
    • Component
    • Identical
    • Two
    • Prolyl
    • 4-hydroxyproline
    • Composed
    • Encodes
    • Gene
    • Key
    • Procollagen
    • Synthesis
    • Activity
  • P4HA1
    • Activity
    • Search
    • Subunit
    • Gene
    • Location
    • Chromosome
    • Human
    • Prolyl
    • Bp
    • Chr
    • Component
    • End
  • p4ha1
    • Activity
    • Search
    • Subunit
    • Gene
    • Location
    • Chromosome
    • Human
    • Prolyl
    • Bp
    • Chr
    • Component
    • End
  • 4-hydroxyproline
    • Procollagen
    • Collagen
    • Prolyl
  • procollagen
    • Prolyl

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the P4HA1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

P4HA1

Nodes9
Edges8
Triples83
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around P4HA1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — P4HA1 · EN edition · Analysis: TopicsToTalkAbout

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