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Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli. Some of them, like benzodiazepines or alcohol, function as psychoactive drugs. The site that an allosteric modulator binds to (i.e., an allosteric site) is not the same one to which an endogenous agonist…

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Overview

Introduction

Classes

Mechanisms

Interaction with agonists

Medical importance

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Map overview Semantic statistics

Allosteric modulator

Nodes63
Edges62
Triples22
Avg. degree1.97
Density0.031746
Components1

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Allosteric modulator

Top relations

related to Introduction · 9
Allosteric modulator → Affinity, Allosteric, Efficacy, If, Modulators, The, They, This, Upon
related to Preventing desensitization · 6
Allosteric modulator → AMPA, Cyclothiazide, Desensitization, Eliminating, Overall, This
related to Modulating binding · 5
Allosteric modulator → Barbiturates, Benzodiazepines, Examples, GABAA, Some
related to Mechanisms · 1
Allosteric modulator → Due
see also · 1
Allosteric modulator → Allosteric

Important terminology Word statistics

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Important terminology

receptor modulators agonist allosteric efficacy agonists also receptors affinity bind lower like modulator function increase work site positive binding response

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Allosteric modulatorrelated to IntroductionAllosteric0.60section
Allosteric modulatorrelated to IntroductionAffinity0.60section
Allosteric modulatorrelated to IntroductionEfficacy0.60section
Allosteric modulatorrelated to IntroductionIf0.60section
Allosteric modulatorrelated to IntroductionThe0.60section
Allosteric modulatorrelated to IntroductionModulators0.60section
Allosteric modulatorrelated to IntroductionThey0.60section
Allosteric modulatorrelated to IntroductionUpon0.60section
Allosteric modulatorrelated to IntroductionThis0.60section
Allosteric modulatorrelated to MechanismsDue0.60section
Allosteric modulatorrelated to Modulating bindingSome0.60section
Allosteric modulatorrelated to Modulating bindingExamples0.60section

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    Min side: 3
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