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DETQ is an experimental drug which acts as a positive allosteric modulator of the dopamine D1 receptor. It increases the D1 receptor-mediated response to endogenous dopamine levels, and was developed as a potential treatment for Parkinson's disease.
Chemogenetic sensitivity tuning & Overview
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dopamine d1 receptor positive allosteric modulator sensitivity drug affinity endogenous significant imaging tonic signals using experimental acts increases receptor-mediated response
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DETQ | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| DETQ | CAS Number | 1638667-81-8 | 1.00 | infobox |
| DETQ | ChEMBL | ChEMBL3421730 | 1.00 | infobox |
| DETQ | ChemSpider | 58987054 | 1.00 | infobox |
| DETQ | Drug class | Dopamine D1 receptor positive allosteric modulator | 1.00 | infobox |
| DETQ | Formula | C22H25Cl2NO3 | 1.00 | infobox |
| DETQ | Molar mass | 422.35 g·mol−1 | 1.00 | infobox |
| DETQ | PubChem CID | 117720272 | 1.00 | infobox |
| DETQ | is a | experimental drug which acts as a positive allosteric modulator of the dopamine D1 receptor | 0.90 | text |
| DETQ | related to Chemogenetic sensitivity tuning | Recent | 0.60 | section |
| DETQ | related to Chemogenetic sensitivity tuning | PAM | 0.60 | section |
| DETQ | related to Chemogenetic sensitivity tuning | D1 | 0.60 | section |
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