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Foam cell

Foam cells are a type of cell that contain cholesterol. These cells are most commonly discussed in the context of cardiovascular diseases as they can form a plaque that can lead to atherosclerosis and trigger myocardial infarction and stroke.

Macrophage-derived foam cells, Other conditions & Infectious diseases

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Key facts & relationships

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FMA
83586
MeSH
D005487
Precursor
monocyte-derived macrophage

Topics to explore

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Overview

Macrophage-derived foam cells

Infectious diseases

Other conditions

Advanced semantic analysis

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Map overview Semantic statistics

Foam cell

Nodes69
Edges68
Triples80
Avg. degree1.97
Density0.028986
Components1

How this topic connects Entity context

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Foam cell

Top relations

related to Formation · 24
Foam cell → AcLDL, CD36, E-selectin, Foam, ICAM-1, In, LDL, M1, M2, Macrophages, METTL3, N6-methyladenosine RNA, Once, OxLDL, P-selectin, PRRs, Recruitment, Research, SR-A, SRs
related to Degradation · 16
Foam cell → ABCA1, ABCG1, AcLDL, ApoA1, ApoE, Esterified, FC, Foam, Free, HDLs, LDL, OxLDL, SR-B1, The, This, While
related to Composition · 14
Foam cell → CCL5, CXC-chemokine, CXCL1, Foam, IL-1, IL-6, LDL, LDL-C, Macrophages, Modified LDL, ROS, The, TNF, VSMC
related to Infectious diseases · 13
Foam cell → As, Chlamydia, Foamy, HIV, IL-18, IL-1β, In, LDL, Mycobacterium, NLRP3, TB, The, Toxoplasma
related to Other conditions · 9
Foam cell → Autoimmunity, Foam, However, INF, Lipid-laden, PDCs, Stimulation, The, Treg
FMA · 1
Foam cell → 83586
MeSH · 1
Foam cell → D005487
Precursor · 1
Foam cell → monocyte-derived macrophage

Important terminology Word statistics

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Important terminology

foam cells macrophages lipoproteins cell cholesterol formation ldl plaque modified also diseases atherosclerosis free smooth muscle macrophage cytokines oxidized receptors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Foam cellFMA835861.00infobox
Foam cellMeSHD0054871.00infobox
Foam cellPrecursormonocyte-derived macrophage1.00infobox
interleukinsinstance ofFoam cells secrete pro-inflammatory cytokines0.80text
Foam cellrelated to CompositionLDL0.60section
Foam cellrelated to CompositionLDL-C0.60section
Foam cellrelated to CompositionThe0.60section
Foam cellrelated to CompositionModified LDL0.60section
Foam cellrelated to CompositionFoam0.60section
Foam cellrelated to CompositionIL-10.60section
Foam cellrelated to CompositionIL-60.60section
Foam cellrelated to CompositionTNF0.60section

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    Min side: 3
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