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Doublecortin

Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X, is a protein that in humans is encoded by the DCX gene.

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Aliases
DCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ATU, 1MJD, 2BQQ, 2XRP, 5IN7, 5IOI, 5IKC, 5IP4, 5IO9
Band
Xq23 · X|X F2
Bgee
ganglionic eminence · ventricular zone · tail of epididymis · endothelial cell · Brodmann area 23
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

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Map overview Semantic statistics

Doublecortin

Nodes34
Edges33
Triples124
Avg. degree1.94
Density0.058824
Components1

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Doublecortin

Top relations

Gene ontology · 20
Doublecortin → axoneme, axoneme assembly, cell differentiation, cell projection, central nervous system development, cytoplasm, cytoskeleton, cytosol, intracellular signal transduction, microtubule, microtubule associated complex, microtubule binding, multicellular organism development, nervous system development, neuron migration, neuron projection, photoreceptor cell development, protein binding, protein kinase binding, retina development in camera-type eye
Bgee · 19
Doublecortin → barrel cortex, Brodmann area 10, Brodmann area 23, Brodmann area 46, endothelial cell, fossa, ganglionic eminence, human fetus, medial ganglionic eminence, middle temporal gyrus, neural tube, olfactory bulb, primary visual cortex, Rostral migratory stream, secondary oocyte, superior cervical ganglion, tail of epididymis, trigeminal ganglion, ventricular zone
RNA expression pattern · 19
Doublecortin → barrel cortex, Brodmann area 10, Brodmann area 23, Brodmann area 46, endothelial cell, fossa, ganglionic eminence, human fetus, medial ganglionic eminence, middle temporal gyrus, neural tube, olfactory bulb, primary visual cortex, Rostral migratory stream, secondary oocyte, superior cervical ganglion, tail of epididymis, trigeminal ganglion, ventricular zone
related to External links · 14
Doublecortin → DCX-Related Disordersdoublecortin, DCX-Related DisordersOMIM, Media, Medicine Medical Subject Headings, MeSH, National Library, Neuronal, O43602, Overview, PDB, PDBe-KB, UniProt, Wikimedia CommonsGeneReviews/NCBI/NIH/UW, Wiktionary-logo-en-v2
related to Clinical significance · 9
Doublecortin → At, Boston, Christopher, Double, In, Joseph Gleeson, The, Walsh, X-linked
related to Function · 7
Doublecortin → BrdU, DCX, Downregulation, Due, Indeed, NeuN, Neuronal
related to Structure · 6
Doublecortin → DC, Doublecortin-like, It, Microtubule, The, These
related to Knock out mouse · 5
Doublecortin → CA3, However, In, The, These
Band · 2
Doublecortin → Xq23, X|X F2
Chr. · 2
Doublecortin → X chromosome (human), X chromosome (mouse)

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Important terminology

dcx protein bp gene chr human band migration neurons neuronal chromosome microtubule mouse also location cells proteins lissencephaly dc expression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DoublecortinAliasesDCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin1.00infobox
DoublecortinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ATU, 1MJD, 2BQQ, 2XRP, 5IN7, 5IOI, 5IKC, 5IP4, 5IO91.00infobox
DoublecortinBandXq231.00infobox
DoublecortinBandX|X F21.00infobox
DoublecortinBgeeganglionic eminence1.00infobox
DoublecortinBgeeventricular zone1.00infobox
DoublecortinBgeetail of epididymis1.00infobox
DoublecortinBgeeendothelial cell1.00infobox
DoublecortinBgeeBrodmann area 231.00infobox
DoublecortinBgeemiddle temporal gyrus1.00infobox
DoublecortinBgeesecondary oocyte1.00infobox
DoublecortinBgeeprimary visual cortex1.00infobox
DoublecortinBgeeBrodmann area 101.00infobox
DoublecortinBgeeBrodmann area 461.00infobox
DoublecortinBgeeRostral migratory stream1.00infobox
DoublecortinBgeetrigeminal ganglion1.00infobox
DoublecortinBgeebarrel cortex1.00infobox
DoublecortinBgeemedial ganglionic eminence1.00infobox
DoublecortinBgeesuperior cervical ganglion1.00infobox
DoublecortinBgeehuman fetus1.00infobox
DoublecortinBgeefossa1.00infobox
DoublecortinBgeeneural tube1.00infobox
DoublecortinBgeeolfactory bulb1.00infobox
DoublecortinBioGPSMore reference expression data1.00infobox
DoublecortinChr.X chromosome (human)1.00infobox
DoublecortinChr.X chromosome (mouse)1.00infobox
DoublecortinDatabasesNCBI: entry; OMA: entry1.00infobox
DoublecortinEnd111,412,429 bp1.00infobox
DoublecortinEnd142,716,307 bp1.00infobox
DoublecortinEnsemblENSG000000772791.00infobox

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