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SLAMF1

Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. Recently SLAMF1 has also been designated CD150 (cluster of differentiation 150).

Regions, Gene & Role of SLAMF1 in diseases

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Aliases
SLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA6
Band
1q23.3 · 1 H3|1 79.54 cM
Bgee
thymus · lymph node · granulocyte · appendix · blood
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

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Overview

Gene

Structure

Signaling

Function

Role of SLAMF1 in diseases

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Map overview Semantic statistics

SLAMF1

Nodes94
Edges93
Triples151
Avg. degree1.98
Density0.021277
Components1

How this topic connects Entity context

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SLAMF1

Top relations

Gene ontology · 41
SLAMF1 → adaptive immune response, antigen binding, cell adhesion, cell surface, external side of plasma membrane, extracellular exosome, extracellular region, identical protein binding, immune system process, innate immune response, integral component of membrane, leukocyte chemotaxis involved in inflammatory response, lymphocyte activation, membrane, myeloid dendritic cell activation involved in immune response, natural killer cell differentiation, natural killer cell proliferation, negative regulation of CD40 signaling pathway, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production
Bgee · 16
SLAMF1 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, pancreatic ductal cell, primary oocyte, rectum, secondary oocyte, spleen, thymus, tibiofemoral joint, tonsil, zygote
RNA expression pattern · 16
SLAMF1 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, pancreatic ductal cell, primary oocyte, rectum, secondary oocyte, spleen, thymus, tibiofemoral joint, tonsil, zygote
related to Gene · 14
SLAMF1 → Alternative, B-cell, Early B-cell, EBF1, From, Furthermore, IL-4R, IRF4, It, Monocytes, NF-kB, NKT, STAT6, The
related to Signaling · 14
SLAMF1 → Because, Binding, EAT-2, Fyn, ITSMs, SAP, SH2, SHIP, SHP-1, SHP-2, Signaling, SLAMF, The, Therefore
related to Function · 11
SLAMF1 → CD8, IFNγ, IL-13, IL-4, In, It, NKT, SAP, SLAMF6, The, This
related to Cancer · 7
SLAMF1 → B-cell, Hodgkin, It, PI3K/Akt/mTOR, Several, T-cell, Therefore
related to Structure · 6
SLAMF1 → However, Ig, Its, ITSMs, SH2, The
related to Viral infections · 3
SLAMF1 → Ig, Morbilliviruses, This
Band · 2
SLAMF1 → 1 H3|1 79.54 cM, 1q23.3

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Important terminology

cells signaling activation receptor gene cell differentiation bp expression human sap protein lymphocytic chr band chromosome role signal regulation molecule

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SLAMF1AliasesSLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 11.00infobox
SLAMF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA61.00infobox
SLAMF1Band1q23.31.00infobox
SLAMF1Band1 H3|1 79.54 cM1.00infobox
SLAMF1Bgeethymus1.00infobox
SLAMF1Bgeelymph node1.00infobox
SLAMF1Bgeegranulocyte1.00infobox
SLAMF1Bgeeappendix1.00infobox
SLAMF1Bgeeblood1.00infobox
SLAMF1Bgeetonsil1.00infobox
SLAMF1Bgeebone marrow cell1.00infobox
SLAMF1Bgeespleen1.00infobox
SLAMF1Bgeerectum1.00infobox
SLAMF1Bgeepancreatic ductal cell1.00infobox
SLAMF1Bgeezygote1.00infobox
SLAMF1Bgeesecondary oocyte1.00infobox
SLAMF1Bgeeprimary oocyte1.00infobox
SLAMF1Bgeetibiofemoral joint1.00infobox
SLAMF1Bgeemesenteric lymph nodes1.00infobox
SLAMF1Bgeeembryo1.00infobox
SLAMF1BioGPSMore reference expression data1.00infobox
SLAMF1Chr.Chromosome 1 (human)1.00infobox
SLAMF1Chr.Chromosome 1 (mouse)1.00infobox
SLAMF1DatabasesNCBI: entry; OMA: entry1.00infobox
SLAMF1End160,647,044 bp1.00infobox
SLAMF1End171,628,752 bp1.00infobox
SLAMF1EnsemblENSG000001170901.00infobox
SLAMF1Entrez65041.00infobox
SLAMF1External IDsOMIM: 603492; MGI: 1351314; GeneCards: SLAMF11.00infobox
SLAMF1Gene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1q23.3Start160,608,106 bpEnd160,647,044 bp1.00infobox

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