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SLAMF1: Regions, Gene & Role of SLAMF1 in diseases

Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. Recently SLAMF1 has also been designated CD150 (cluster of differentiation 150).

Language: English [EN]
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SLAMF1 topic overview

The analysis highlights Regions, Gene and Role of SLAMF1 in diseases as prominent areas in the source structure around SLAMF1.

Related topics
87
Source areas
6
Connected nodes
93
Extracted relationships
151
Concept neighborhoods
36
Bridge connections
93

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Gene · 24 topics
Role of SLAMF1 in diseases · 22 topics
Function · 14 topics
Signaling · 14 topics
Overview · 7 topics
Structure · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA6
Band
1q23.3 · 1 H3|1 79.54 cM
Bgee
thymus · lymph node · granulocyte · appendix · blood
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Structure

Signaling

Function

Role of SLAMF1 in diseases

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SLAMF1 connects Entity context

The extracted context around SLAMF1 shows recurring relationship patterns in the source. For example, SLAMF1 → adaptive immune response, antigen binding, cell adhesion, cell surface, external side of plasma membrane, extracellular exosome, extracellular region, identical protein binding, immune system process, innate immune response, integral component of membrane, leukocyte chemotaxis involved in inflammatory response, lymphocyte activation, membrane, myeloid dendritic cell activation involved in immune response, natural killer cell differentiation, natural killer cell proliferation, negative regulation of CD40 signaling pathway, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production Another extracted example is SLAMF1 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, pancreatic ductal cell, primary oocyte, rectum, secondary oocyte, spleen, thymus, tibiofemoral joint, tonsil, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

SLAMF1

Top relations

Gene ontology · 41
SLAMF1 → adaptive immune response, antigen binding, cell adhesion, cell surface, external side of plasma membrane, extracellular exosome, extracellular region, identical protein binding, immune system process, innate immune response, integral component of membrane, leukocyte chemotaxis involved in inflammatory response, lymphocyte activation, membrane, myeloid dendritic cell activation involved in immune response, natural killer cell differentiation, natural killer cell proliferation, negative regulation of CD40 signaling pathway, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production
Bgee · 16
SLAMF1 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, pancreatic ductal cell, primary oocyte, rectum, secondary oocyte, spleen, thymus, tibiofemoral joint, tonsil, zygote
RNA expression pattern · 16
SLAMF1 → appendix, blood, bone marrow cell, embryo, granulocyte, lymph node, mesenteric lymph nodes, pancreatic ductal cell, primary oocyte, rectum, secondary oocyte, spleen, thymus, tibiofemoral joint, tonsil, zygote
related to Gene · 14
SLAMF1 → Alternative, B-cell, Early B-cell, EBF1, From, Furthermore, IL-4R, IRF4, It, Monocytes, NF-kB, NKT, STAT6, The
related to Signaling · 14
SLAMF1 → Because, Binding, EAT-2, Fyn, ITSMs, SAP, SH2, SHIP, SHP-1, SHP-2, Signaling, SLAMF, The, Therefore
related to Function · 11
SLAMF1 → CD8, IFNγ, IL-13, IL-4, In, It, NKT, SAP, SLAMF6, The, This
related to Cancer · 7
SLAMF1 → B-cell, Hodgkin, It, PI3K/Akt/mTOR, Several, T-cell, Therefore
related to Structure · 6
SLAMF1 → However, Ig, Its, ITSMs, SH2, The
related to Viral infections · 3
SLAMF1 → Ig, Morbilliviruses, This
Band · 2
SLAMF1 → 1 H3|1 79.54 cM, 1q23.3

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells signaling activation receptor gene cell differentiation bp expression human sap protein lymphocytic chr band chromosome role signal regulation molecule

SLAMF1 relationships Subject–Predicate–Object triples

TTTA extracted 151 structured relationships around SLAMF1. Examples in this analysis include SLAMF1 → Aliases → SLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 1 and SLAMF1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SLAMF1AliasesSLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 11.00infobox
SLAMF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA61.00infobox
SLAMF1Band1q23.31.00infobox
SLAMF1Band1 H3|1 79.54 cM1.00infobox
SLAMF1Bgeethymus1.00infobox
SLAMF1Bgeelymph node1.00infobox
SLAMF1Bgeegranulocyte1.00infobox
SLAMF1Bgeeappendix1.00infobox
SLAMF1Bgeeblood1.00infobox
SLAMF1Bgeetonsil1.00infobox
SLAMF1Bgeebone marrow cell1.00infobox
SLAMF1Bgeespleen1.00infobox
SLAMF1Bgeerectum1.00infobox
SLAMF1Bgeepancreatic ductal cell1.00infobox
SLAMF1Bgeezygote1.00infobox
SLAMF1Bgeesecondary oocyte1.00infobox
SLAMF1Bgeeprimary oocyte1.00infobox
SLAMF1Bgeetibiofemoral joint1.00infobox
SLAMF1Bgeemesenteric lymph nodes1.00infobox
SLAMF1Bgeeembryo1.00infobox
SLAMF1BioGPSMore reference expression data1.00infobox
SLAMF1Chr.Chromosome 1 (human)1.00infobox
SLAMF1Chr.Chromosome 1 (mouse)1.00infobox
SLAMF1DatabasesNCBI: entry; OMA: entry1.00infobox
SLAMF1End160,647,044 bp1.00infobox
SLAMF1End171,628,752 bp1.00infobox
SLAMF1EnsemblENSG000001170901.00infobox
SLAMF1Entrez65041.00infobox
SLAMF1External IDsOMIM: 603492; MGI: 1351314; GeneCards: SLAMF11.00infobox
SLAMF1Gene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1q23.3Start160,608,106 bpEnd160,647,044 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SLAMF1 bring nearby vocabulary together. In this analysis, examples include Expression, Receptor and Cancer. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SLAMF1
    • Expression
    • Receptor
    • Cancer
    • Interaction
    • Function
    • System
    • Transmembrane
    • Production
    • Sap
    • Cell
    • External
    • Location
  • slamf1
    • Expression
    • Receptor
    • Cancer
    • Interaction
    • Function
    • System
    • Transmembrane
    • Production
    • Sap
    • Cell
    • External
    • Location
  • protein
    • Transmembrane
    • Gene
    • Region
    • Cell
    • Signaling
    • External
    • Function
    • Immune
    • Location
    • Proliferation
    • System
    • Virus
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • External
    • Function
    • Signaling
    • Band
    • Molecule
    • Lymphocytic
    • Protein
  • cluster of differentiation
    • Cell
    • Signal
    • Function
    • Proliferation
    • Production
    • Regulation
    • Expression
    • Receptor
    • External
    • Immune
    • Location
    • Receptors
  • signaling lymphocytic activation molecule
    • Molecule
    • Signaling
    • Activation
    • Family
    • Lymphocytic
    • Gene
    • Cancer
    • External
    • Slamf1
    • Function
    • Location
    • Chromosome
  • immune system
    • System
    • Regulation
    • External
    • Expression
    • Function
    • Location
    • Proliferation
    • Receptors
    • Virus
    • Band
    • Chromosome
    • Human
  • chromosome 1
    • Human
    • Bp
    • Location
    • Band
    • External
    • Gene
    • Function
    • Signaling
    • Family
    • Immune
    • Proliferation
    • System

Connections between topic areas Semantic bridges

For SLAMF1, one of the stronger structural bridges in this analysis connects SLAMF1 with Gene. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SLAMF1Gene · splits 69 ⟂ 25
SLAMF1Role of SLAMF1 in diseases · splits 71 ⟂ 23
SLAMF1Signaling · splits 79 ⟂ 15
SLAMF1Function · splits 79 ⟂ 15
SLAMF1Overview · splits 86 ⟂ 8
SLAMF1Structure · splits 87 ⟂ 7

Map overview Semantic statistics

SLAMF1

Nodes94
Edges93
Triples151
Avg. degree1.98
Density0.021277
Components1

Source & methodology

TTTA analyzes the structure around SLAMF1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Gene & Role of SLAMF1 in diseases, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SLAMF1 · EN edition · Analysis: TopicsToTalkAbout

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