Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

SH2D1A

SH2 domain–containing protein 1A is a protein that in humans is encoded by the SH2D1A gene. It is often called SLAM-associated protein (symbol SAP), where "SLAM" refers to signaling lymphocytic activation molecules. It is a SH2 domain–containing molecule (part of a family of such molecules) that plays a role in SLAM signaling. A putative function is as…

Art, Interactions & Overview

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around SH2D1A. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M27
Band
Xq25 · X|X A4
Bgee
thymus · lymph node · granulocyte · blood · appendix
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

SH2D1A

Nodes18
Edges17
Triples69
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

SH2D1A

Top relations

Bgee · 15
SH2D1A → appendix, blood, bone marrow, bone marrow cell, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, neural layer of retina, retinal pigment epithelium, spermatid, spleen, testicle, thymus
RNA expression pattern · 15
SH2D1A → appendix, blood, bone marrow, bone marrow cell, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, neural layer of retina, retinal pigment epithelium, spermatid, spleen, testicle, thymus
Gene ontology · 12
SH2D1A → adaptive immune response, cell-cell signaling, cellular defense response, cytoplasm, cytosol, humoral immune response, immune system process, innate immune response, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of signal transduction, protein binding, regulation of immune response
related to Interactions · 4
SH2D1A → CD84, DOK1, FYN, LY9
Band · 2
SH2D1A → Xq25, X|X A4
Chr. · 2
SH2D1A → X chromosome (human), X chromosome (mouse)
End · 2
SH2D1A → 124,373,197 bp, 41,618,207 bp
Aliases · 1
SH2D1A → SH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A
Available structures · 1
SH2D1A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M27
BioGPS · 1
SH2D1A → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band protein signaling chromosome slam sh2 domain containing sap location molecules family mouse fyn 1a function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SH2D1AAliasesSH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A1.00infobox
SH2D1AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M271.00infobox
SH2D1ABandXq251.00infobox
SH2D1ABandX|X A41.00infobox
SH2D1ABgeethymus1.00infobox
SH2D1ABgeelymph node1.00infobox
SH2D1ABgeegranulocyte1.00infobox
SH2D1ABgeeblood1.00infobox
SH2D1ABgeeappendix1.00infobox
SH2D1ABgeespleen1.00infobox
SH2D1ABgeebone marrow1.00infobox
SH2D1ABgeetesticle1.00infobox
SH2D1ABgeegallbladder1.00infobox
SH2D1ABgeebone marrow cell1.00infobox
SH2D1ABgeeneural layer of retina1.00infobox
SH2D1ABgeespermatid1.00infobox
SH2D1ABgeeembryo1.00infobox
SH2D1ABgeemesenteric lymph nodes1.00infobox
SH2D1ABgeeretinal pigment epithelium1.00infobox
SH2D1ABioGPSMore reference expression data1.00infobox
SH2D1AChr.X chromosome (human)1.00infobox
SH2D1AChr.X chromosome (mouse)1.00infobox
SH2D1ADatabasesNCBI: entry; OMA: entry1.00infobox
SH2D1AEnd124,373,197 bp1.00infobox
SH2D1AEnd41,618,207 bp1.00infobox
SH2D1AEnsemblENSG000001839181.00infobox
SH2D1AEntrez40681.00infobox
SH2D1AExternal IDsOMIM: 300490; MGI: 1328352; GeneCards: SH2D1A1.00infobox
SH2D1AGene location (Human)Gene location (Human)Chr.X chromosome (human)BandXq25Start124,227,868 bpEnd124,373,197 bp1.00infobox
SH2D1AGene location (Mouse)Gene location (Mouse)Chr.X chromosome (mouse)BandX|X A4Start41,591,330 bpEnd41,618,207 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.