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SH2 domain–containing protein 1A is a protein that in humans is encoded by the SH2D1A gene. It is often called SLAM-associated protein (symbol SAP), where "SLAM" refers to signaling lymphocytic activation molecules. It is a SH2 domain–containing molecule (part of a family of such molecules) that plays a role in SLAM signaling. A putative function is as…
The analysis highlights Art, Interactions and Overview as prominent areas in the source structure around SH2D1A.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SH2D1A shows recurring relationship patterns in the source. For example, SH2D1A → appendix, blood, bone marrow, bone marrow cell, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, neural layer of retina, retinal pigment epithelium, spermatid, spleen, testicle, thymus Another extracted example is SH2D1A → adaptive immune response, cell-cell signaling, cellular defense response, cytoplasm, cytosol, humoral immune response, immune system process, innate immune response, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of signal transduction, protein binding, regulation of immune response. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp chr human band protein signaling chromosome slam sh2 domain containing sap location molecules family mouse fyn 1a function
TTTA extracted 69 structured relationships around SH2D1A. Examples in this analysis include SH2D1A → Aliases → SH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A and SH2D1A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M27. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SH2D1A | Aliases | SH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A | 1.00 | infobox |
| SH2D1A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M27 | 1.00 | infobox |
| SH2D1A | Band | Xq25 | 1.00 | infobox |
| SH2D1A | Band | X|X A4 | 1.00 | infobox |
| SH2D1A | Bgee | thymus | 1.00 | infobox |
| SH2D1A | Bgee | lymph node | 1.00 | infobox |
| SH2D1A | Bgee | granulocyte | 1.00 | infobox |
| SH2D1A | Bgee | blood | 1.00 | infobox |
| SH2D1A | Bgee | appendix | 1.00 | infobox |
| SH2D1A | Bgee | spleen | 1.00 | infobox |
| SH2D1A | Bgee | bone marrow | 1.00 | infobox |
| SH2D1A | Bgee | testicle | 1.00 | infobox |
| SH2D1A | Bgee | gallbladder | 1.00 | infobox |
| SH2D1A | Bgee | bone marrow cell | 1.00 | infobox |
| SH2D1A | Bgee | neural layer of retina | 1.00 | infobox |
| SH2D1A | Bgee | spermatid | 1.00 | infobox |
| SH2D1A | Bgee | embryo | 1.00 | infobox |
| SH2D1A | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| SH2D1A | Bgee | retinal pigment epithelium | 1.00 | infobox |
| SH2D1A | BioGPS | More reference expression data | 1.00 | infobox |
| SH2D1A | Chr. | X chromosome (human) | 1.00 | infobox |
| SH2D1A | Chr. | X chromosome (mouse) | 1.00 | infobox |
| SH2D1A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SH2D1A | End | 124,373,197 bp | 1.00 | infobox |
| SH2D1A | End | 41,618,207 bp | 1.00 | infobox |
| SH2D1A | Ensembl | ENSG00000183918 | 1.00 | infobox |
| SH2D1A | Entrez | 4068 | 1.00 | infobox |
| SH2D1A | External IDs | OMIM: 300490; MGI: 1328352; GeneCards: SH2D1A | 1.00 | infobox |
| SH2D1A | Gene location (Human) | Gene location (Human)Chr.X chromosome (human)BandXq25Start124,227,868 bpEnd124,373,197 bp | 1.00 | infobox |
| SH2D1A | Gene location (Mouse) | Gene location (Mouse)Chr.X chromosome (mouse)BandX|X A4Start41,591,330 bpEnd41,618,207 bp | 1.00 | infobox |
The concept neighborhoods around SH2D1A bring nearby vocabulary together. In this analysis, examples include Signaling, Sh2d1a and Activation. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SH2D1A, one of the stronger structural bridges in this analysis connects SH2D1A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SH2D1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SH2D1A · EN edition · Analysis: TopicsToTalkAbout