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PTK2B

Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.

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2.7.10.2
Aliases
PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…
Band
8p21.2 · 14 D1|14 34.36 cM
Bgee
right hemisphere of cerebellum · granulocyte · Brodmann area 10 · right frontal lobe · paraflocculus of cerebellum
BioGPS
More reference expression data

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Map overview Semantic statistics

PTK2B

Nodes36
Edges35
Triples231
Avg. degree1.94
Density0.055556
Components1

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PTK2B

Top relations

Gene ontology · 150
PTK2B → 3-phosphoinositide-dependent protein kinase binding, actin filament organization, activation of GTPase activity, activation of Janus kinase activity, adaptive immune response, angiogenesis, apical dendrite, apoptotic process, ATP binding, axon, blood vessel endothelial cell migration, bone resorption, calmodulin-dependent protein kinase activity, cell adhesion, cell body, cell cortex, cell differentiation, cell junction, cell projection, cell surface receptor signaling pathway
Bgee · 19
PTK2B → anterior cingulate cortex, bone marrow cell, Brodmann area 10, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, granulocyte, hippocampus proper, monocyte, olfactory tubercle, paraflocculus of cerebellum, perirhinal cortex, piriform cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, superior frontal gyrus
RNA expression pattern · 19
PTK2B → anterior cingulate cortex, bone marrow cell, Brodmann area 10, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, granulocyte, hippocampus proper, monocyte, olfactory tubercle, paraflocculus of cerebellum, perirhinal cortex, piriform cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, superior frontal gyrus
related to Interactions · 18
PTK2B → ASAP2, BCAR1, Cbl, DLG3, DLG4, Ewing, FYN, Gelsolin, GRIN2A, NPHP1, Paxillin, PITPNM1, PTPN11, PTPN6, RAS, RB1CC1, SORBS2, Src
Band · 2
PTK2B → 14 D1|14 34.36 cM, 8p21.2
Chr. · 2
PTK2B → Chromosome 14 (mouse), Chromosome 8 (human)
End · 2
PTK2B → 27,459,391 bp, 66,518,501 bp
2.7.10.2 · 1
PTK2B → ↗
Aliases · 1
PTK2B → PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta
Available structures · 1
PTK2B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…

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Important terminology

protein tyrosine gene bp kinase chr human band chromosome enzyme encoded activation location activity phosphorylation mouse signaling calcium beta function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PTK2B2.7.10.21.00infobox
PTK2BAliasesPTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta1.00infobox
PTK2BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…1.00infobox
PTK2BBand8p21.21.00infobox
PTK2BBand14 D1|14 34.36 cM1.00infobox
PTK2BBgeeright hemisphere of cerebellum1.00infobox
PTK2BBgeegranulocyte1.00infobox
PTK2BBgeeBrodmann area 101.00infobox
PTK2BBgeeright frontal lobe1.00infobox
PTK2BBgeeparaflocculus of cerebellum1.00infobox
PTK2BBgeemonocyte1.00infobox
PTK2BBgeespleen1.00infobox
PTK2BBgeeBrodmann area 91.00infobox
PTK2BBgeebone marrow cell1.00infobox
PTK2BBgeeanterior cingulate cortex1.00infobox
PTK2BBgeedentate gyrus of hippocampal formation granule cell1.00infobox
PTK2BBgeesuperior frontal gyrus1.00infobox
PTK2BBgeeCA3 field1.00infobox
PTK2BBgeeprimary visual cortex1.00infobox
PTK2BBgeeolfactory tubercle1.00infobox
PTK2BBgeepiriform cortex1.00infobox
PTK2BBgeeentorhinal cortex1.00infobox
PTK2BBgeehippocampus proper1.00infobox
PTK2BBgeeperirhinal cortex1.00infobox
PTK2BBioGPSMore reference expression data1.00infobox
PTK2BChr.Chromosome 8 (human)1.00infobox
PTK2BChr.Chromosome 14 (mouse)1.00infobox
PTK2BDatabasesNCBI: entry; OMA: entry1.00infobox
PTK2BEnd27,459,391 bp1.00infobox
PTK2BEnd66,518,501 bp1.00infobox

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