Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

PTK2B: Interactions, Function & Overview

Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

PTK2B topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around PTK2B.

Related topics
32
Source areas
3
Connected nodes
35
Extracted relationships
231
Concept neighborhoods
11
Bridge connections
35

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 20 topics
Function · 10 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.2
Aliases
PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…
Band
8p21.2 · 14 D1|14 34.36 cM
Bgee
right hemisphere of cerebellum · granulocyte · Brodmann area 10 · right frontal lobe · paraflocculus of cerebellum
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PTK2B connects Entity context

The extracted context around PTK2B shows recurring relationship patterns in the source. For example, PTK2B → 3-phosphoinositide-dependent protein kinase binding, actin filament organization, activation of GTPase activity, activation of Janus kinase activity, adaptive immune response, angiogenesis, apical dendrite, apoptotic process, ATP binding, axon, blood vessel endothelial cell migration, bone resorption, calmodulin-dependent protein kinase activity, cell adhesion, cell body, cell cortex, cell differentiation, cell junction, cell projection, cell surface receptor signaling pathway Another extracted example is PTK2B → anterior cingulate cortex, bone marrow cell, Brodmann area 10, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, granulocyte, hippocampus proper, monocyte, olfactory tubercle, paraflocculus of cerebellum, perirhinal cortex, piriform cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

PTK2B

Top relations

Gene ontology · 150
PTK2B → 3-phosphoinositide-dependent protein kinase binding, actin filament organization, activation of GTPase activity, activation of Janus kinase activity, adaptive immune response, angiogenesis, apical dendrite, apoptotic process, ATP binding, axon, blood vessel endothelial cell migration, bone resorption, calmodulin-dependent protein kinase activity, cell adhesion, cell body, cell cortex, cell differentiation, cell junction, cell projection, cell surface receptor signaling pathway
Bgee · 19
PTK2B → anterior cingulate cortex, bone marrow cell, Brodmann area 10, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, granulocyte, hippocampus proper, monocyte, olfactory tubercle, paraflocculus of cerebellum, perirhinal cortex, piriform cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, superior frontal gyrus
RNA expression pattern · 19
PTK2B → anterior cingulate cortex, bone marrow cell, Brodmann area 10, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, granulocyte, hippocampus proper, monocyte, olfactory tubercle, paraflocculus of cerebellum, perirhinal cortex, piriform cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, spleen, superior frontal gyrus
related to Interactions · 18
PTK2B → ASAP2, BCAR1, Cbl, DLG3, DLG4, Ewing, FYN, Gelsolin, GRIN2A, NPHP1, Paxillin, PITPNM1, PTPN11, PTPN6, RAS, RB1CC1, SORBS2, Src
Band · 2
PTK2B → 14 D1|14 34.36 cM, 8p21.2
Chr. · 2
PTK2B → Chromosome 14 (mouse), Chromosome 8 (human)
End · 2
PTK2B → 27,459,391 bp, 66,518,501 bp
2.7.10.2 · 1
PTK2B → ↗
Aliases · 1
PTK2B → PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta
Available structures · 1
PTK2B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein tyrosine gene bp kinase chr human band chromosome enzyme encoded activation location activity phosphorylation mouse signaling calcium beta function

PTK2B relationships Subject–Predicate–Object triples

TTTA extracted 231 structured relationships around PTK2B. Examples in this analysis include PTK2B → 2.7.10.2 → ↗ and PTK2B → Aliases → PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PTK2B2.7.10.21.00infobox
PTK2BAliasesPTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein tyrosine kinase 2 beta1.00infobox
PTK2BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LK4, 3CC6, 3ET7, 3FZO, 3FZP, 3FZR, 3FZS, 3FZT, 3GM1, 3GM2, 3GM3, 3H3C, 3U3F, 4EKU, 4H1J, 4H1M, 4R32, 4XEK,…1.00infobox
PTK2BBand8p21.21.00infobox
PTK2BBand14 D1|14 34.36 cM1.00infobox
PTK2BBgeeright hemisphere of cerebellum1.00infobox
PTK2BBgeegranulocyte1.00infobox
PTK2BBgeeBrodmann area 101.00infobox
PTK2BBgeeright frontal lobe1.00infobox
PTK2BBgeeparaflocculus of cerebellum1.00infobox
PTK2BBgeemonocyte1.00infobox
PTK2BBgeespleen1.00infobox
PTK2BBgeeBrodmann area 91.00infobox
PTK2BBgeebone marrow cell1.00infobox
PTK2BBgeeanterior cingulate cortex1.00infobox
PTK2BBgeedentate gyrus of hippocampal formation granule cell1.00infobox
PTK2BBgeesuperior frontal gyrus1.00infobox
PTK2BBgeeCA3 field1.00infobox
PTK2BBgeeprimary visual cortex1.00infobox
PTK2BBgeeolfactory tubercle1.00infobox
PTK2BBgeepiriform cortex1.00infobox
PTK2BBgeeentorhinal cortex1.00infobox
PTK2BBgeehippocampus proper1.00infobox
PTK2BBgeeperirhinal cortex1.00infobox
PTK2BBioGPSMore reference expression data1.00infobox
PTK2BChr.Chromosome 8 (human)1.00infobox
PTK2BChr.Chromosome 14 (mouse)1.00infobox
PTK2BDatabasesNCBI: entry; OMA: entry1.00infobox
PTK2BEnd27,459,391 bp1.00infobox
PTK2BEnd66,518,501 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PTK2B bring nearby vocabulary together. In this analysis, examples include Tyrosine, Function and Pdb. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PTK2B
    • Tyrosine
    • Function
    • Pdb
    • Q14289
    • Search
    • Uniprot
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • ptk2b
    • Tyrosine
    • Function
    • Pdb
    • Q14289
    • Search
    • Uniprot
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • enzyme
    • Ptk2b
    • Function
    • Search
    • Kinase
    • Activity
    • Gene
    • Location
    • Tyrosine
    • Chromosome
    • Human
    • Protein
    • Bp
  • gene
    • Ptk2b
    • Kinase
    • Location
    • Tyrosine
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • D1
    • End
    • Function
  • map kinase signaling pathway
    • Ptk2b
    • Tyrosine
    • Protein
    • Enzyme
    • Gene
    • Beta
    • Function
    • Membrane
    • Pdb
    • Q14289
    • Search
    • Uniprot
  • protein kinase c
    • Ptk2b
    • Tyrosine
    • Kinase
    • Protein
    • Enzyme
    • Gene
    • Encoded
    • Beta
    • Function
    • Membrane
    • Pdb
    • Q14289
  • cbl gene
    • Ptk2b
    • Kinase
    • Location
    • Tyrosine
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • D1
    • End
    • Function
  • ras p21 protein activator 1
    • Tyrosine
    • Kinase
    • Encoded
    • Ptk2b
    • Gene
    • Activity
    • Calcium
    • Enzyme
    • Beta
    • Function
    • Membrane
    • Pdb

Connections between topic areas Semantic bridges

For PTK2B, one of the stronger structural bridges in this analysis connects PTK2B with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PTK2BInteractions · splits 15 ⟂ 21
PTK2BFunction · splits 25 ⟂ 11
PTK2BOverview · splits 33 ⟂ 3

Map overview Semantic statistics

PTK2B

Nodes36
Edges35
Triples231
Avg. degree1.94
Density0.055556
Components1

Source & methodology

TTTA analyzes the structure around PTK2B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PTK2B · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.