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NPHP1: Interactions & Overview

Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene.

Language: English [EN]
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NPHP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around NPHP1.

Related topics
7
Source areas
2
Connected nodes
9
Extracted relationships
94
Concept neighborhoods
5
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 5 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NPHP1, JBTS4, NPH1, SLSN1, nephrocystin 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1N
Band
2q13 · 2|2 F1
Bgee
right uterine tube · bronchial epithelial cell · olfactory zone of nasal mucosa · muscle of thigh · left testis
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NPHP1 connects Entity context

The extracted context around NPHP1 shows recurring relationship patterns in the source. For example, NPHP1 → actin cytoskeleton organization, adherens junction, bicellular tight junction, cell differentiation, cell junction, cell projection, cell projection organization, cell-cell adhesion, cell-cell junction, ciliary basal body-plasma membrane docking, ciliary transition zone, cilium, cytoplasm, cytoskeleton, cytosol, excretion, membrane, motile cilium, photoreceptor connecting cilium, positive regulation of bicellular tight junction assembly Another extracted example is NPHP1 → anterior pituitary, bronchial epithelial cell, buccal mucosa cell, coelomic epithelium, Epithelium of choroid plexus, esophagus, extensor digitorum longus muscle, gastrocnemius muscle, gonad, left testis, muscle of thigh, olfactory zone of nasal mucosa, proximal tubule, right kidney, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, utricle. Use these groups to spot repeated connection types before inspecting the individual relationships.

NPHP1

Top relations

Gene ontology · 27
NPHP1 → actin cytoskeleton organization, adherens junction, bicellular tight junction, cell differentiation, cell junction, cell projection, cell projection organization, cell-cell adhesion, cell-cell junction, ciliary basal body-plasma membrane docking, ciliary transition zone, cilium, cytoplasm, cytoskeleton, cytosol, excretion, membrane, motile cilium, photoreceptor connecting cilium, positive regulation of bicellular tight junction assembly
Bgee · 20
NPHP1 → anterior pituitary, bronchial epithelial cell, buccal mucosa cell, coelomic epithelium, Epithelium of choroid plexus, esophagus, extensor digitorum longus muscle, gastrocnemius muscle, gonad, left testis, muscle of thigh, olfactory zone of nasal mucosa, proximal tubule, right kidney, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, utricle
RNA expression pattern · 20
NPHP1 → anterior pituitary, bronchial epithelial cell, buccal mucosa cell, coelomic epithelium, Epithelium of choroid plexus, esophagus, extensor digitorum longus muscle, gastrocnemius muscle, gonad, left testis, muscle of thigh, olfactory zone of nasal mucosa, proximal tubule, right kidney, right testis, right uterine tube, seminiferous tubule, spermatid, spermatocyte, utricle
related to Interactions · 4
NPHP1 → BCAR1, Filamin, INVS, PTK2B
Band · 2
NPHP1 → 2q13, 2|2 F1
Chr. · 2
NPHP1 → Chromosome 2 (human), Chromosome 2 (mouse)
End · 2
NPHP1 → 110,205,066 bp, 127,630,817 bp
Aliases · 1
NPHP1 → NPHP1, JBTS4, NPH1, SLSN1, nephrocystin 1
Available structures · 1
NPHP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1N
BioGPS · 1
NPHP1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band chromosome protein location mouse function search 205 066 end 110 630 817 nephrocystin-1 humans encoded

NPHP1 relationships Subject–Predicate–Object triples

TTTA extracted 94 structured relationships around NPHP1. Examples in this analysis include NPHP1 → Aliases → NPHP1, JBTS4, NPH1, SLSN1, nephrocystin 1 and NPHP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1N. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NPHP1AliasesNPHP1, JBTS4, NPH1, SLSN1, nephrocystin 11.00infobox
NPHP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1N1.00infobox
NPHP1Band2q131.00infobox
NPHP1Band2|2 F11.00infobox
NPHP1Bgeeright uterine tube1.00infobox
NPHP1Bgeebronchial epithelial cell1.00infobox
NPHP1Bgeeolfactory zone of nasal mucosa1.00infobox
NPHP1Bgeemuscle of thigh1.00infobox
NPHP1Bgeeleft testis1.00infobox
NPHP1Bgeeright testis1.00infobox
NPHP1Bgeeanterior pituitary1.00infobox
NPHP1Bgeebuccal mucosa cell1.00infobox
NPHP1Bgeegonad1.00infobox
NPHP1Bgeegastrocnemius muscle1.00infobox
NPHP1Bgeespermatocyte1.00infobox
NPHP1Bgeespermatid1.00infobox
NPHP1Bgeeseminiferous tubule1.00infobox
NPHP1Bgeeesophagus1.00infobox
NPHP1BgeeEpithelium of choroid plexus1.00infobox
NPHP1Bgeecoelomic epithelium1.00infobox
NPHP1Bgeeextensor digitorum longus muscle1.00infobox
NPHP1Bgeeutricle1.00infobox
NPHP1Bgeeright kidney1.00infobox
NPHP1Bgeeproximal tubule1.00infobox
NPHP1BioGPSMore reference expression data1.00infobox
NPHP1Chr.Chromosome 2 (human)1.00infobox
NPHP1Chr.Chromosome 2 (mouse)1.00infobox
NPHP1DatabasesNCBI: entry; OMA: entry1.00infobox
NPHP1End110,205,066 bp1.00infobox
NPHP1End127,630,817 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NPHP1 bring nearby vocabulary together. In this analysis, examples include Function, Protein and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Chromosome
    • Human
    • Nphp1
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Protein
    • Search
    • Band
  • NPHP1
    • Function
    • Protein
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
    • Reading
    • References
    • End
  • nphp1
    • Function
    • Protein
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
    • Reading
    • References
    • End
  • interactions
    • Reading
    • References
    • Search
    • Location
    • Human
    • Nphp1
  • protein
    • Search

Connections between topic areas Semantic bridges

For NPHP1, one of the stronger structural bridges in this analysis connects NPHP1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NPHP1Interactions · splits 4 ⟂ 6
NPHP1Overview · splits 7 ⟂ 3

Map overview Semantic statistics

NPHP1

Nodes10
Edges9
Triples94
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around NPHP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NPHP1 · EN edition · Analysis: TopicsToTalkAbout

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