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PSMD5: Measurement, Clinical significance & Interactions

26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.

Language: English [EN]
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PSMD5 topic overview

The analysis highlights Measurement, Clinical significance and Interactions as prominent areas in the source structure around PSMD5.

Related topics
54
Source areas
3
Connected nodes
57
Extracted relationships
96
Concept neighborhoods
8
Bridge connections
57

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 50 topics
Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PSMD5, S5B, proteasome 26S subunit, non-ATPase 5
Band
9q33.2 · 2|2 B
Bgee
hair follicle · tibia · epithelium of lactiferous gland · lactiferous duct · islet of Langerhans
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PSMD5 connects Entity context

The extracted context around PSMD5 shows recurring relationship patterns in the source. For example, PSMD5 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, Fc-epsilon receptor signaling pathway, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, proteasome accessory complex, proteasome assembly, proteasome complex, proteasome regulatory particle assembly, proteasome regulatory particle, base subcomplex, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein deubiquitination Another extracted example is PSMD5 → Achilles tendon, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, epithelium of lactiferous gland, fetal liver hematopoietic progenitor cell, gums, hair follicle, islet of Langerhans, lactiferous duct, lower lobe of lung, medial ganglionic eminence, neural tube, Paneth cell, periodontal fiber, primary oocyte, proximal tubule, right kidney, secondary oocyte, tibia. Use these groups to spot repeated connection types before inspecting the individual relationships.

PSMD5

Top relations

Gene ontology · 32
PSMD5 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytosol, Fc-epsilon receptor signaling pathway, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, proteasome accessory complex, proteasome assembly, proteasome complex, proteasome regulatory particle assembly, proteasome regulatory particle, base subcomplex, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein deubiquitination
Bgee · 19
PSMD5 → Achilles tendon, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, epithelium of lactiferous gland, fetal liver hematopoietic progenitor cell, gums, hair follicle, islet of Langerhans, lactiferous duct, lower lobe of lung, medial ganglionic eminence, neural tube, Paneth cell, periodontal fiber, primary oocyte, proximal tubule, right kidney, secondary oocyte, tibia
RNA expression pattern · 19
PSMD5 → Achilles tendon, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, epithelium of lactiferous gland, fetal liver hematopoietic progenitor cell, gums, hair follicle, islet of Langerhans, lactiferous duct, lower lobe of lung, medial ganglionic eminence, neural tube, Paneth cell, periodontal fiber, primary oocyte, proximal tubule, right kidney, secondary oocyte, tibia
Band · 2
PSMD5 → 2|2 B, 9q33.2
Chr. · 2
PSMD5 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
PSMD5 → 120,842,951 bp, 34,764,980 bp
Aliases · 1
PSMD5 → PSMD5, S5B, proteasome 26S subunit, non-ATPase 5
BioGPS · 1
PSMD5 → More reference expression data
Databases · 1
PSMD5 → NCBI: entry; OMA: entry
Ensembl · 1
PSMD5 → ENSG00000095261

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

proteasome gene ups bp chr human band protein chromosome clinical non-atpase function role complex 26s subunit location proteasomes degradation inflammatory

PSMD5 relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around PSMD5. Examples in this analysis include PSMD5 → Aliases → PSMD5, S5B, proteasome 26S subunit, non-ATPase 5 and PSMD5 → Band → 9q33.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PSMD5AliasesPSMD5, S5B, proteasome 26S subunit, non-ATPase 51.00infobox
PSMD5Band9q33.21.00infobox
PSMD5Band2|2 B1.00infobox
PSMD5Bgeehair follicle1.00infobox
PSMD5Bgeetibia1.00infobox
PSMD5Bgeeepithelium of lactiferous gland1.00infobox
PSMD5Bgeelactiferous duct1.00infobox
PSMD5Bgeeislet of Langerhans1.00infobox
PSMD5BgeeAchilles tendon1.00infobox
PSMD5Bgeesecondary oocyte1.00infobox
PSMD5Bgeeperiodontal fiber1.00infobox
PSMD5Bgeelower lobe of lung1.00infobox
PSMD5Bgeegums1.00infobox
PSMD5Bgeefetal liver hematopoietic progenitor cell1.00infobox
PSMD5Bgeeprimary oocyte1.00infobox
PSMD5Bgeeright kidney1.00infobox
PSMD5Bgeemedial ganglionic eminence1.00infobox
PSMD5Bgeeendothelial cell of lymphatic vessel1.00infobox
PSMD5Bgeeneural tube1.00infobox
PSMD5Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PSMD5Bgeeproximal tubule1.00infobox
PSMD5BgeePaneth cell1.00infobox
PSMD5BioGPSMore reference expression data1.00infobox
PSMD5Chr.Chromosome 9 (human)1.00infobox
PSMD5Chr.Chromosome 2 (mouse)1.00infobox
PSMD5DatabasesNCBI: entry; OMA: entry1.00infobox
PSMD5End120,842,951 bp1.00infobox
PSMD5End34,764,980 bp1.00infobox
PSMD5EnsemblENSG000000952611.00infobox
PSMD5Entrez57111.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PSMD5 bring nearby vocabulary together. In this analysis, examples include Regulatory, Location and Subunit. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Subunit
    • Transcription
    • Chromosome
    • Degradation
    • Human
    • Non-atpase
    • Psmd5
    • Bp
    • Chr
    • Proteasome
    • Mouse
  • ubiquitin–proteasome system
    • Protein
    • Function
    • Assembly
    • Complex
    • Gene
    • Psmd5
    • Clinical
    • Regulatory
    • Location
    • Regulation
    • Subunit
    • Transcription
  • PSMD5
    • Regulatory
    • Location
    • Subunit
    • Chromosome
    • Function
    • Human
    • Bp
    • Chr
    • Mouse
    • Tumor
    • 19s
    • Assembly
  • psmd5
    • Regulatory
    • Location
    • Subunit
    • Chromosome
    • Function
    • Human
    • Bp
    • Chr
    • Mouse
    • Tumor
    • 19s
    • Assembly
  • clinical significance
    • Diseases
    • Proteasome
    • Assembly
    • Complex
    • Location
    • Subunit
    • Subunits
    • Chromosome
    • Function
    • Human
    • Non-atpase
    • Proteasomes
  • proteolysis
    • Plays
    • Responses
    • Role
    • Regulation
    • Transcription
    • Ups
    • Inflammatory
  • transcription factors
    • Degradation
    • Tumor
    • Development
    • Proteolysis
    • Ups
  • von hippel–lindau tumor suppressor
    • Ups

Connections between topic areas Semantic bridges

For PSMD5, one of the stronger structural bridges in this analysis connects PSMD5 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PSMD5Clinical significance · splits 7 ⟂ 51
PSMD5Overview · splits 55 ⟂ 3
PSMD5Interactions · splits 55 ⟂ 3

Map overview Semantic statistics

PSMD5

Nodes58
Edges57
Triples96
Avg. degree1.97
Density0.034483
Components1

Source & methodology

TTTA analyzes the structure around PSMD5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Clinical significance & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PSMD5 · EN edition · Analysis: TopicsToTalkAbout

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