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PSMC2: Measurement, Interactions & Overview
26S protease regulatory subunit 7, also known as 26S proteasome AAA-ATPase subunit Rpt1, is an enzyme that in humans is encoded by the PSMC2 gene This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex. Six 26S proteasome AAA-ATPase subunits (Rpt1 (this protein), Rpt2, Rpt3, Rpt4, Rpt5, and Rpt6) together with four…
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PSMC2 topic overview
The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around PSMC2.
Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
124
Concept neighborhoods
10
Bridge connections
19
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Overview · 12 topics
Interactions · 3 topics
Function · 1 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Skeletal muscle tissue of biceps brachii · epithelium of nasopharynx · sperm · gingival epithelium · visceral pleura
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry
Explore all related topics Closing gaps
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
How PSMC2 connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around PSMC2 shows recurring relationship patterns in the source. For example, PSMC2 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, cytoplasm, cytoplasmic ribonucleoprotein granule, cytosol, cytosolic proteasome complex, dendritic spine, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, hydrolase activity, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation, NIK/NF-kappaB signaling Another extracted example is PSMC2 → Epithelium of choroid plexus, epithelium of nasopharynx, facial motor nucleus, fossa, gingival epithelium, hair follicle, medullary collecting duct, motor neuron, palpebral conjunctiva, parietal pleura, primitive streak, seminiferous tubule, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, skin of hip, sperm, superior cervical ganglion, tibia, ureter, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
PSMC2
Top relations
Gene ontology· 55
PSMC2 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, ATPase activity, cytoplasm, cytoplasmic ribonucleoprotein granule, cytosol, cytosolic proteasome complex, dendritic spine, extracellular region, Fc-epsilon receptor signaling pathway, ficolin-1-rich granule lumen, hydrolase activity, interleukin-1-mediated signaling pathway, MAPK cascade, membrane, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, neutrophil degranulation, NIK/NF-kappaB signaling
Bgee· 20
PSMC2 → Epithelium of choroid plexus, epithelium of nasopharynx, facial motor nucleus, fossa, gingival epithelium, hair follicle, medullary collecting duct, motor neuron, palpebral conjunctiva, parietal pleura, primitive streak, seminiferous tubule, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, skin of hip, sperm, superior cervical ganglion, tibia, ureter, visceral pleura
RNA expression pattern· 20
PSMC2 → Epithelium of choroid plexus, epithelium of nasopharynx, facial motor nucleus, fossa, gingival epithelium, hair follicle, medullary collecting duct, motor neuron, palpebral conjunctiva, parietal pleura, primitive streak, seminiferous tubule, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, skin of hip, sperm, superior cervical ganglion, tibia, ureter, visceral pleura
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 124 structured relationships around PSMC2. Examples in this analysis include PSMC2 → Aliases → PSMC2, MSS1, Nbla10058, S7, proteasome 26S subunit, ATPase 2, RPT1 and PSMC2 → Band → 7q22.1. The table shows each extracted connection, where it came from and its confidence.
Concept neighborhoods group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around PSMC2 bring nearby vocabulary together. In this analysis, examples include Chromosome, Human and Atpase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
proteasome
Psmc2
Rpt1
Atpase
Location
Regulatory
Protein
Particle
Subunit
Assembly
Bp
Chr
Chromosome
gene
Chromosome
Psmc2
Location
Human
Band
Bp
Chr
Atpase
Proteasome
One
Assembly
Rpt1
PSMC2
Chromosome
Human
Atpase
Location
Assembly
Band
Bp
Chr
Rpt1
Protein
Subunit
Subunits
psmc2
Chromosome
Human
Atpase
Location
Assembly
Band
Bp
Chr
Rpt1
Protein
Subunit
Subunits
rpt2
Rpt3
Rpt5
Rpt6
Rpn1
Rpn13
Subunit
Atpases
Cp
Ring
Sub
Subunits
20s
rpn1
Rpn13
Ring
Rpt1
Rpt3
Rpt5
Rpt6
Atpases
Rpt2
Sub
Three
Subunits
Subunit
rpt3
Rpt5
Rpt6
Rpn1
Rpn13
Atpases
Cp
Ring
Sub
Subunits
20s
Subunit
rpn13
Sub
Rpt1
Rpt3
Rpt5
Rpt6
Atpases
Ring
Rpt2
Subunits
Assembly
Subunit
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For PSMC2, one of the stronger structural bridges in this analysis connects PSMC2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
PSMC2
Nodes20
Edges19
Triples124
Avg. degree1.9
Density0.1
Components1
Source & methodology
TTTA analyzes the structure around PSMC2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PSMC2 · EN edition · Analysis: TopicsToTalkAbout
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