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Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect. Many are physical contacts with molecular associations between chains that occur in a cell…
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proteins protein interactions interaction ppis methods molecular two many ppi yeast interacting cell one using gene prediction databases networks system
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| His3 | instance of | The Y2H is based on the functional reconstitution of the yeast transcription factor Gal4 and subsequent activation of a selective reporter | 0.80 | text |
| Genomic Context | instance of | some of the interactions in the STRING database are only predicted by computational methods | 0.80 | text |
| not experimentally verified | instance of | some of the interactions in the STRING database are only predicted by computational methods | 0.80 | text |
| Jactive modules | instance of | There are some methods | 0.80 | text |
| MoBaS | instance of | There are some methods | 0.80 | text |
| yeast two-hybrid screens or 'affinity purification | instance of | protein interaction networks are often constructed as a result of lab experiments | 0.80 | text |
| subsequent mass spectrometry techniques | instance of | protein interaction networks are often constructed as a result of lab experiments | 0.80 | text |
| allosteric sites | instance of | Several properties of PPI | 0.80 | text |
| hotspots | instance of | Several properties of PPI | 0.80 | text |
| have been incorporated into drug-design strategies | instance of | Several properties of PPI | 0.80 | text |
| Protein–protein interaction | has method | Diverse | 0.60 | section |
| Protein–protein interaction | has method | PPIs | 0.60 | section |
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