5α-Reductase 2 deficiency

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around 5α-Reductase 2 deficiency. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Society and culture

Third gender Gender socialisation Self-identify BMJ Clitoridectomies

11 related topics

Signs and symptoms

Vasa deferentia Seminal vesicles Epididymides Ejaculatory ducts Testes

11 related topics

Diagnosis

Karyotyping SRY Leukocytes Sex chromosome Human chorionic gonadotropin (hCG)

11 related topics

Overview

Autosomal recessive Condition Mutations SRD5A2 Gene

18 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Causes: Mutations in the SRD5A2 gene.
Other names: 5-alpha reductase deficiency, Pseudovaginal perineoscrotal hypospadias 46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency.
Specialty: Medical genetics

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Autosomal recessive
Condition Medical condition
Mutations Genetic mutation
SRD5A2
Gene
Enzyme
5α-reductase type 2
Testosterone
5α-dihydrotestosterone
Sexual differentiation
Atypical sex development Disorders of sex development
Genitalia
Assigned female at birth
Assigned male at birth
Micropenis
Hypospadias
Puberty
Male pattern hair loss Pattern hair loss

Signs and symptoms

Genetics

Deletion Deletion (genetics)
Missense mutations Missense mutation
Splice junction mutations Splice site mutation

Mechanism

5α-Reductase type 2 5α-Reductase
Androgen receptor
Male sexual differentiation Sexual differentiation in humans

Diagnosis

Karyotyping Karyotype
SRY
Leukocytes Leukocyte
Sex chromosome
Human chorionic gonadotropin (hCG) Human chorionic gonadotropin
Testosterone enanthate
Gas chromatography–mass spectrometry
Ultrasonography
Genitography
Voiding cystourethrography
MRI

Management

Epidemiology

History

Clitoromegaly

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes75

Edges74

Triples8

Avg. degree1.97

Density0.026667

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

5α-Reductase 2 deficiency

Top relations

Causes · 1

5α-Reductase 2 deficiency → Mutations in the SRD5A2 gene.

Other names · 1

5α-Reductase 2 deficiency → 5-alpha reductase deficiency, Pseudovaginal perineoscrotal hypospadias 46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency.

Specialty · 1

5α-Reductase 2 deficiency → Medical genetics

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

srd5a2 male sex genitalia dht 5αr2d deficiency affected development mutations gene testosterone individuals hypospadias people androgen type 5αr2 female birth

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
5α-Reductase 2 deficiency	Causes	Mutations in the SRD5A2 gene.	1.00	infobox
5α-Reductase 2 deficiency	Other names	5-alpha reductase deficiency, Pseudovaginal perineoscrotal hypospadias 46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency.	1.00	infobox
5α-Reductase 2 deficiency	Specialty	Medical genetics	1.00	infobox
partial androgen insensitivity syndrome	instance of	XY DSD from other causes	0.80	text
17β-hydroxysteroid dehydrogenase 3 deficiency	instance of	XY DSD from other causes	0.80	text
urethral	instance of	mass spectrometry.Ultrasonography is the primary means for assessing internal reproductive organs for diagnosis while genitography and voiding cystourethrography are used to res…	0.80	text
vaginal tracts	instance of	mass spectrometry.Ultrasonography is the primary means for assessing internal reproductive organs for diagnosis while genitography and voiding cystourethrography are used to res…	0.80	text
childhood gonadectomy	instance of	and social situation.Female sex rearing in 5αR2D individuals involves surgical procedures	0.80	text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3