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GTF2F1: Measurement, Interactions & Overview

General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.

Language: English [EN]
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GTF2F1 topic overview

The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around GTF2F1.

Related topics
13
Source areas
2
Connected nodes
15
Extracted relationships
111
Concept neighborhoods
8
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 11 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GTF2F1, general transcription factor IIF, polypeptide 1, 74kDa, BTF4, RAP74, TF2F1, TFIIF, general transcription factor IIF subunit 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F3U, 1I27, 1J2X, 1NHA, 1ONV, 2K7L, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Band
19p13.3 · 17|17 D
Bgee
cerebellum · cerebellar cortex · cerebellar hemisphere · left testis · right hemisphere of cerebellum
BioGPS
n/a
Chr.
Chromosome 19 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GTF2F1 connects Entity context

The extracted context around GTF2F1 shows recurring relationship patterns in the source. For example, GTF2F1 → 7-methylguanosine mRNA capping, cell junction, DNA binding, fibroblast growth factor receptor signaling pathway, intracellular membrane-bounded organelle, mRNA splicing, via spliceosome, negative regulation of protein binding, nucleoplasm, nucleus, phosphatase activator activity, positive regulation of catalytic activity, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of viral transcription, promoter-specific chromatin binding, protein binding, protein domain specific binding, protein phosphatase binding, protein-containing complex, regulation of transcription, DNA-templated Another extracted example is GTF2F1 → anterior pituitary, cerebellar cortex, cerebellar hemisphere, cerebellum, genital tubercle, left ovary, left testis, neural layer of retina, otic placode, otic vesicle, prefrontal cortex, primary oocyte, primitive streak, right hemisphere of cerebellum, right testis, saccule, seminiferous tubule, superior frontal gyrus, tail of embryo, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

GTF2F1

Top relations

Gene ontology · 33
GTF2F1 → 7-methylguanosine mRNA capping, cell junction, DNA binding, fibroblast growth factor receptor signaling pathway, intracellular membrane-bounded organelle, mRNA splicing, via spliceosome, negative regulation of protein binding, nucleoplasm, nucleus, phosphatase activator activity, positive regulation of catalytic activity, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of viral transcription, promoter-specific chromatin binding, protein binding, protein domain specific binding, protein phosphatase binding, protein-containing complex, regulation of transcription, DNA-templated
Bgee · 20
GTF2F1 → anterior pituitary, cerebellar cortex, cerebellar hemisphere, cerebellum, genital tubercle, left ovary, left testis, neural layer of retina, otic placode, otic vesicle, prefrontal cortex, primary oocyte, primitive streak, right hemisphere of cerebellum, right testis, saccule, seminiferous tubule, superior frontal gyrus, tail of embryo, yolk sac
RNA expression pattern · 20
GTF2F1 → anterior pituitary, cerebellar cortex, cerebellar hemisphere, cerebellum, genital tubercle, left ovary, left testis, neural layer of retina, otic placode, otic vesicle, prefrontal cortex, primary oocyte, primitive streak, right hemisphere of cerebellum, right testis, saccule, seminiferous tubule, superior frontal gyrus, tail of embryo, yolk sac
related to Interactions · 9
GTF2F1 → CTDP1, Factor II, GTF2H4, HNRPU, MED21, POLR2A, Serum, TAF1, TATA
related to External links · 6
GTF2F1 → FactorBookGTF2F1 This, Medicine, Medicine Medical Subject Headings, MeSH, National Library, United States National Library
Band · 2
GTF2F1 → 17|17 D, 19p13.3
Chr. · 2
GTF2F1 → Chromosome 17 (mouse), Chromosome 19 (human)
End · 2
GTF2F1 → 57,318,288 bp, 6,393,981 bp
Aliases · 1
GTF2F1 → GTF2F1, general transcription factor IIF, polypeptide 1, 74kDa, BTF4, RAP74, TF2F1, TFIIF, general transcription factor IIF subunit 1
Available structures · 1
GTF2F1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F3U, 1I27, 1J2X, 1NHA, 1ONV, 2K7L, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human chr band transcription factor gene chromosome 19 protein general location mouse ii iif subunit external tfiif search 393

GTF2F1 relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around GTF2F1. Examples in this analysis include GTF2F1 → Aliases → GTF2F1, general transcription factor IIF, polypeptide 1, 74kDa, BTF4, RAP74, TF2F1, TFIIF, general transcription factor IIF subunit 1 and GTF2F1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F3U, 1I27, 1J2X, 1NHA, 1ONV, 2K7L, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GTF2F1AliasesGTF2F1, general transcription factor IIF, polypeptide 1, 74kDa, BTF4, RAP74, TF2F1, TFIIF, general transcription factor IIF subunit 11.00infobox
GTF2F1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1F3U, 1I27, 1J2X, 1NHA, 1ONV, 2K7L, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY61.00infobox
GTF2F1Band19p13.31.00infobox
GTF2F1Band17|17 D1.00infobox
GTF2F1Bgeecerebellum1.00infobox
GTF2F1Bgeecerebellar cortex1.00infobox
GTF2F1Bgeecerebellar hemisphere1.00infobox
GTF2F1Bgeeleft testis1.00infobox
GTF2F1Bgeeright hemisphere of cerebellum1.00infobox
GTF2F1Bgeeright testis1.00infobox
GTF2F1Bgeeleft ovary1.00infobox
GTF2F1Bgeeprefrontal cortex1.00infobox
GTF2F1Bgeeanterior pituitary1.00infobox
GTF2F1Bgeesuperior frontal gyrus1.00infobox
GTF2F1Bgeesaccule1.00infobox
GTF2F1Bgeeotic placode1.00infobox
GTF2F1Bgeeotic vesicle1.00infobox
GTF2F1Bgeeseminiferous tubule1.00infobox
GTF2F1Bgeeneural layer of retina1.00infobox
GTF2F1Bgeetail of embryo1.00infobox
GTF2F1Bgeeprimitive streak1.00infobox
GTF2F1Bgeeprimary oocyte1.00infobox
GTF2F1Bgeeyolk sac1.00infobox
GTF2F1Bgeegenital tubercle1.00infobox
GTF2F1BioGPSn/a1.00infobox
GTF2F1Chr.Chromosome 19 (human)1.00infobox
GTF2F1Chr.Chromosome 17 (mouse)1.00infobox
GTF2F1DatabasesNCBI: entry; OMA: entry1.00infobox
GTF2F1End6,393,981 bp1.00infobox
GTF2F1End57,318,288 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GTF2F1 bring nearby vocabulary together. In this analysis, examples include Transcription, Protein and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GTF2F1
    • Transcription
    • Protein
    • Human
    • Ii
    • Iif
    • Search
    • Subunit
    • Tfiif
    • Location
    • Chromosome
    • Bp
    • Chr
  • gtf2f1
    • Transcription
    • Protein
    • Human
    • Ii
    • Iif
    • Search
    • Subunit
    • Tfiif
    • Location
    • Chromosome
    • Bp
    • Chr
  • gene
    • General
    • Location
    • Chromosome
    • Gtf2f1
    • Transcription
    • Bp
    • Chr
    • End
    • Human
    • Iif
    • Mouse
    • Search
  • serum response factor
    • Gtf2f1
    • Transcription
    • General
    • Protein
    • Gene
    • Human
    • Ii
    • Iif
    • Search
    • Subunit
    • Tfiif
    • Location
  • transcription factor ii b
    • Factor
    • Gtf2f1
    • Transcription
    • General
    • Protein
    • Gene
    • Human
    • Ii
    • Iif
    • Response
    • Search
    • Subunit
  • tata binding protein
    • Response
    • Gtf2f1
    • Transcription
    • Ii
    • Domain
    • End
    • Mouse
    • Search
    • Tfiif
    • Binding
    • General
    • Human
  • protein
    • Gtf2f1
    • Transcription
    • Ii
    • Binding
    • Human
    • Humans
    • Response
    • Domain
    • End
    • Mouse
    • Search
    • Subunit
  • interactions
    • Also
    • External
    • Links
    • Reading
    • References
    • See
    • Search
    • Subunit
    • Tfiif
    • Location
    • Chromosome
    • Transcription

Connections between topic areas Semantic bridges

For GTF2F1, one of the stronger structural bridges in this analysis connects GTF2F1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GTF2F1Interactions · splits 4 ⟂ 12
GTF2F1Overview · splits 13 ⟂ 3

Map overview Semantic statistics

GTF2F1

Nodes16
Edges15
Triples111
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around GTF2F1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GTF2F1 · EN edition · Analysis: TopicsToTalkAbout

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