Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene.
The analysis highlights Interactions, Clinical significance and Function as prominent areas in the source structure around Cyclin-dependent kinase 8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A focused starting point derived from the topic graph, ranked independently of the source article order.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Cyclin-dependent kinase 8 shows recurring relationship patterns in the source. For example, Cyclin-dependent kinase 8 → ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, mediator complex, nucleolus, nucleoplasm, nucleotide binding, nucleus, phosphorylation, positive regulation of transcription by RNA polymerase II, protein binding, protein kinase activity, protein phosphorylation, protein serine/threonine kinase activity, protein-containing complex, regulation of cell cycle, regulation of mitotic cell cycle, regulation of transcription, DNA-templated, RNA polymerase II CTD heptapeptide repeat kinase activity, transcription initiation from RNA polymerase II promoter Another extracted example is Cyclin-dependent kinase 8 → amniotic fluid, buccal mucosa cell, endothelial cell, ganglionic eminence, jejunal mucosa, mandibular prominence, maxillary prominence, medullary collecting duct, muscle layer of sigmoid colon, Paneth cell, parietal pleura, primitive streak, secondary oocyte, somite, sperm, ureter, vestibular sensory epithelium, visceral pleura, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cdk8 gene human bp kinase chr band cell protein notch chromosome 13 location transcription cyclin-dependent binding mediator complex function activity
TTTA extracted 88 structured relationships around Cyclin-dependent kinase 8. Examples in this analysis include Cyclin-dependent kinase 8 → 2.7.11.22 → ↗ and Cyclin-dependent kinase 8 → Aliases → CDK8, K35, cyclin-dependent kinase 8, cyclin dependent kinase 8, IDDHBA. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Cyclin-dependent kinase 8 | 2.7.11.22 | ↗ | 1.00 | infobox |
| Cyclin-dependent kinase 8 | 2.7.11.23 | ↗ | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Aliases | CDK8, K35, cyclin-dependent kinase 8, cyclin dependent kinase 8, IDDHBA | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3RGF, 4F6S, 4F6U, 4F6W, 4F70, 4F7J, 4F7L, 4F7N, 4F7S, 4G6L, 4CRL, 5HBH, 5CEI, 5FGK, 5HBE, 5BNJ, 5HBJ, 5HVY,… | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Band | 13q12.13 | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Band | 5|5 G3 | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | buccal mucosa cell | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | secondary oocyte | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | sperm | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | parietal pleura | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | endothelial cell | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | visceral pleura | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | amniotic fluid | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | jejunal mucosa | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | ganglionic eminence | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | ureter | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | primitive streak | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | zygote | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | medullary collecting duct | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | mandibular prominence | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | Paneth cell | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | somite | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Bgee | maxillary prominence | 1.00 | infobox |
| Cyclin-dependent kinase 8 | BioGPS | More reference expression data | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Chr. | Chromosome 13 (human) | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| Cyclin-dependent kinase 8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Cyclin-dependent kinase 8 | End | 26,405,238 bp | 1.00 | infobox |
The concept neighborhoods around Cyclin-dependent kinase 8 bring nearby vocabulary together. In this analysis, examples include Search, Cyclin-dependent and Kinase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Cyclin-dependent kinase 8, one of the stronger structural bridges in this analysis connects Cyclin-dependent kinase 8 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Cyclin-dependent kinase 8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical significance & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Cyclin-dependent kinase 8 · EN edition · Analysis: TopicsToTalkAbout