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SND1: Interactions, Clinical significance & Overview

Staphylococcal nuclease domain-containing protein 1 also known as 100 kDa coactivator or Tudor domain-containing protein 11 (TDRD11) is a protein that in humans is encoded by the SND1 gene. SND1 is a main component of RISC complex and plays an important role in miRNA function. SND1 is Tudor domain containing protein and Tudor Proteins are highly…

Language: English [EN]
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SND1 topic overview

The analysis highlights Interactions, Clinical significance and Overview as prominent areas in the source structure around SND1.

Related topics
19
Source areas
3
Connected nodes
22
Extracted relationships
103
Concept neighborhoods
8
Bridge connections
22

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 8 topics
Clinical significance · 6 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.31.1
Aliases
SND1, TDRD11, p100, staphylococcal nuclease and tudor domain containing 1, Tudor-SN
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E6N, 2HQE, 2HQX, 2O4X, 3BDL, 3OMC, 3OMG, 4QMG
Band
7q32.1 · 6|6 A3.3
Bgee
body of pancreas · stromal cell of endometrium · islet of Langerhans · parotid gland · epithelium of colon
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SND1 connects Entity context

The extracted context around SND1 shows recurring relationship patterns in the source. For example, SND1 → cadherin binding, cytoplasm, cytosol, dense body, endonuclease activity, endoribonuclease activity, extracellular exosome, gene silencing, hydrolase activity, melanosome, membrane, miRNA catabolic process, mitochondrion, nuclease activity, nucleic acid binding, nucleic acid phosphodiester bond hydrolysis, nucleus, osteoblast differentiation, protein binding, regulation of cell cycle process Another extracted example is SND1 → anterior pituitary, body of pancreas, canal of the cervix, dentate gyrus of hippocampal formation granule cell, epiblast, epithelium of colon, islet of Langerhans, lacrimal gland, left ovary, lip, molar, parotid gland, placenta, right ovary, smooth muscle tissue, stroma of bone marrow, stromal cell of endometrium, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

SND1

Top relations

Gene ontology · 30
SND1 → cadherin binding, cytoplasm, cytosol, dense body, endonuclease activity, endoribonuclease activity, extracellular exosome, gene silencing, hydrolase activity, melanosome, membrane, miRNA catabolic process, mitochondrion, nuclease activity, nucleic acid binding, nucleic acid phosphodiester bond hydrolysis, nucleus, osteoblast differentiation, protein binding, regulation of cell cycle process
Bgee · 19
SND1 → anterior pituitary, body of pancreas, canal of the cervix, dentate gyrus of hippocampal formation granule cell, epiblast, epithelium of colon, islet of Langerhans, lacrimal gland, left ovary, lip, molar, parotid gland, placenta, right ovary, smooth muscle tissue, stroma of bone marrow, stromal cell of endometrium, ventricular zone, yolk sac
RNA expression pattern · 19
SND1 → anterior pituitary, body of pancreas, canal of the cervix, dentate gyrus of hippocampal formation granule cell, epiblast, epithelium of colon, islet of Langerhans, lacrimal gland, left ovary, lip, molar, parotid gland, placenta, right ovary, smooth muscle tissue, stroma of bone marrow, stromal cell of endometrium, ventricular zone, yolk sac
related to Interactions · 5
SND1 → MYB, PIM1, POLR2A, RBPJ, STAT6
related to Clinical significance · 4
SND1 → II, Mir-184, NF-kappaB, TGFβ
Band · 2
SND1 → 6|6 A3.3, 7q32.1
Chr. · 2
SND1 → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
SND1 → 128,092,609 bp, 28,935,161 bp
3.1.31.1 · 1
SND1 → ↗
Aliases · 1
SND1 → SND1, TDRD11, p100, staphylococcal nuclease and tudor domain containing 1, Tudor-SN

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human chr band protein gene chromosome tudor nuclease also location mirna mouse staphylococcal tdrd11 component risc complex function domain

SND1 relationships Subject–Predicate–Object triples

TTTA extracted 103 structured relationships around SND1. Examples in this analysis include SND1 → 3.1.31.1 → ↗ and SND1 → Aliases → SND1, TDRD11, p100, staphylococcal nuclease and tudor domain containing 1, Tudor-SN. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SND13.1.31.11.00infobox
SND1AliasesSND1, TDRD11, p100, staphylococcal nuclease and tudor domain containing 1, Tudor-SN1.00infobox
SND1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E6N, 2HQE, 2HQX, 2O4X, 3BDL, 3OMC, 3OMG, 4QMG1.00infobox
SND1Band7q32.11.00infobox
SND1Band6|6 A3.31.00infobox
SND1Bgeebody of pancreas1.00infobox
SND1Bgeestromal cell of endometrium1.00infobox
SND1Bgeeislet of Langerhans1.00infobox
SND1Bgeeparotid gland1.00infobox
SND1Bgeeepithelium of colon1.00infobox
SND1Bgeecanal of the cervix1.00infobox
SND1Bgeeleft ovary1.00infobox
SND1Bgeesmooth muscle tissue1.00infobox
SND1Bgeeanterior pituitary1.00infobox
SND1Bgeeright ovary1.00infobox
SND1Bgeelacrimal gland1.00infobox
SND1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
SND1Bgeeyolk sac1.00infobox
SND1Bgeelip1.00infobox
SND1Bgeeepiblast1.00infobox
SND1Bgeeventricular zone1.00infobox
SND1Bgeemolar1.00infobox
SND1Bgeestroma of bone marrow1.00infobox
SND1Bgeeplacenta1.00infobox
SND1BioGPSn/a1.00infobox
SND1Chr.Chromosome 7 (human)1.00infobox
SND1Chr.Chromosome 6 (mouse)1.00infobox
SND1DatabasesNCBI: entry; OMA: entry1.00infobox
SND1End128,092,609 bp1.00infobox
SND1End28,935,161 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SND1 bring nearby vocabulary together. In this analysis, examples include Tudor, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SND1
    • Tudor
    • Gene
    • Human
    • Activity
    • Carcinoma
    • Complex
    • Component
    • Containing
    • Domain
    • Expression
    • Function
    • Granule
  • snd1
    • Tudor
    • Gene
    • Human
    • Activity
    • Carcinoma
    • Complex
    • Component
    • Containing
    • Domain
    • Expression
    • Function
    • Granule
  • protein
    • Granule
    • Also
    • Tudor
    • Snd1
    • Gene
    • Kda
    • Known
    • A3
    • Activity
    • Carcinoma
    • Complex
    • Component
  • gene
    • Location
    • Nuclease
    • Chromosome
    • A3
    • Activity
    • Bp
    • Chr
    • End
    • Human
    • Mouse
    • Search
    • Staphylococcal
  • risc complex
    • Complex
    • Component
    • Function
    • Mirna
    • Risc
    • A3
    • Activity
    • Carcinoma
    • End
    • Expression
    • Granule
    • Hepatocellular
  • mirna
    • Function
    • Risc
    • A3
    • Activity
    • Carcinoma
    • End
    • Expression
    • Granule
    • Hepatocellular
    • Mouse
    • Search
    • Location
  • tudor domain
    • Containing
    • Domain
    • Staphylococcal
    • Tdrd11
    • Tudor
    • Nuclease
    • Gene
    • Protein
    • Activity
    • Domain-containing
    • Kda
    • Known
  • hepatocellular carcinoma
    • Hepatocellular
    • Human
    • Complex
    • Component
    • End
    • Expression
    • Function
    • Granule
    • Mirna
    • Mouse
    • Promotes
    • Risc

Connections between topic areas Semantic bridges

For SND1, one of the stronger structural bridges in this analysis connects SND1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SND1Interactions · splits 14 ⟂ 9
SND1Clinical significance · splits 16 ⟂ 7
SND1Overview · splits 17 ⟂ 6

Map overview Semantic statistics

SND1

Nodes23
Edges22
Triples103
Avg. degree1.91
Density0.086957
Components1

Source & methodology

TTTA analyzes the structure around SND1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SND1 · EN edition · Analysis: TopicsToTalkAbout

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