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Internexin: Measurement & Regions

Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 kDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in…

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Internexin topic overview

The analysis highlights Measurement and Regions as prominent areas in the source structure around Internexin.

Related topics
52
Source areas
4
Connected nodes
56
Extracted relationships
43
Concept neighborhoods
16
Bridge connections
56

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 18 topics
Function and expression · 15 topics
Disease associations · 10 topics
Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
NEF5
Domains
InterPro
HGNC
6057
Locus
Chr. 10 q24
NCBI gene
9118
OMIM
605338

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function and expression

Disease associations

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Internexin connects Entity context

The extracted context around Internexin shows recurring relationship patterns in the source. For example, Internexin → Alpha-internexin, III, In Ching, IV, NF-M's, Not, The, This Another extracted example is Internexin → As, In, It, NF-H, NF-L, NF-M, They. Use these groups to spot repeated connection types before inspecting the individual relationships.

Internexin

Top relations

related to Structure · 8
Internexin → Alpha-internexin, III, In Ching, IV, NF-M's, Not, The, This
related to Function and expression · 7
Internexin → As, In, It, NF-H, NF-L, NF-M, They
related to Disease associations · 6
Internexin → Alzheimer's, HTLV-1, In HTLV-1, Lewy, Parkinson's, Tax
related to External links · 4
Internexin → Interactions, Medicine Medical Subject Headings, MeSH, National Library
Alt. symbols · 1
Internexin → NEF5
Domains · 1
Internexin → InterPro
HGNC · 1
Internexin → 6057
Locus · 1
Internexin → Chr. 10 q24
NCBI gene · 1
Internexin → 9118
OMIM · 1
Internexin → 605338

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

α-internexin filament intermediate alpha-internexin protein expressed neurofilament central structure also form proteins nervous system neurofilaments filaments axonal rod highly formation

Internexin relationships Subject–Predicate–Object triples

TTTA extracted 43 structured relationships around Internexin. Examples in this analysis include Internexin → Alt. symbols → NEF5 and Internexin → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
InternexinAlt. symbolsNEF51.00infobox
InternexinDomainsInterPro1.00infobox
InternexinHGNC60571.00infobox
InternexinLocusChr. 10 q241.00infobox
InternexinNCBI gene91181.00infobox
InternexinOMIM6053381.00infobox
InternexinRefSeqNM_0327271.00infobox
InternexinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
InternexinStructuresSwiss-model1.00infobox
InternexinSymbolINA1.00infobox
InternexinUniProtQ163521.00infobox
Internexinis abrain and central nervous system filament that is involved in neuronal development and has been suggested to play a role in axonal outgrowth0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Internexin bring nearby vocabulary together. In this analysis, examples include Neurofilaments, Filament and Intermediate. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • intermediate filament
    • Filament
    • Intermediate
    • Filaments
    • Form
    • Internexin
    • Step
    • Formation
    • Neurofilaments
    • Rod
    • Cells
    • Present
    • Α-internexin
  • central nervous system
    • System
    • Nervous
    • Axonal
    • Outgrowth
    • Region
    • Development
    • Domain
    • Protein
    • Rod
    • Α-internexin
    • Cells
    • Neuroblasts
  • rod domain
    • Rod
    • Structure
    • Alpha
    • Region
    • Step
    • Q24
    • Domains
    • Head
    • Nm
    • Formation
    • Highly
    • Form
  • nervous system
    • System
    • Axonal
    • Outgrowth
    • Development
    • Protein
    • Α-internexin
    • Cells
    • Neuroblasts
    • Present
    • Neurons
    • Triplet
    • Neurofilament
  • cerebellar granule cells
    • Present
    • Neurons
    • Triplet
    • Neurofilament
    • Nervous
    • Protein
    • Proteins
    • System
    • Central
    • Expressed
    • Intermediate
    • Filament
  • cells
    • Present
    • Neurons
    • Triplet
    • Neurofilament
    • Nervous
    • Protein
    • Proteins
    • System
    • Central
    • Expressed
    • Intermediate
    • Filament
  • axonal
    • Outgrowth
    • May
    • Development
    • Nervous
    • System
    • Α-internexin
    • Optic
    • Filaments
    • Highly
    • Protein
    • Central
    • Expressed
  • neurofilament
    • Neurons
    • Triplet
    • Proteins
    • Expressed
    • Α-internexin
    • Cells
    • Originally
    • Development
    • Nervous
    • Protein
    • System
    • Central

Connections between topic areas Semantic bridges

For Internexin, one of the stronger structural bridges in this analysis connects Internexin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Internexin — Structure · splits 38 ⟂ 19
Internexin — Function and expression · splits 41 ⟂ 16
Internexin — Disease associations · splits 46 ⟂ 11
Internexin — Overview · splits 47 ⟂ 10

Map overview Semantic statistics

Internexin

Nodes57
Edges56
Triples43
Avg. degree1.96
Density0.035088
Components1

Source & methodology

TTTA analyzes the structure around Internexin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Internexin · EN edition · Analysis: TopicsToTalkAbout

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