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Internexin: Measurement & Regions

Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 kDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in…

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Internexin topic overview

The analysis highlights Measurement and Regions as prominent areas in the source structure around Internexin.

Related topics
51
Source areas
4
Connected nodes
55
Extracted relationships
32
Related term clusters
16
Bridge connections
55

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 17 topics
Function and expression · 15 topics
Disease associations · 10 topics
Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
NEF5
Domains
InterPro
HGNC
6057
Locus
Chr. 10 q24
NCBI gene
9118
OMIM
605338

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function and expression

Disease associations

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Internexin connects Entity context

The extracted context around Internexin shows recurring relationship patterns in the source. For example, Internexin → Alzheimer's, HTLV-1, In HTLV-1, Lewy, Parkinson's, Tax Another extracted example is Internexin → Alpha-internexin, III, In Ching, IV, NF-M's. Use these groups to spot repeated connection types before inspecting the individual relationships.

Internexin

Top relations

related to Disease associations · 6
Internexin → Alzheimer's, HTLV-1, In HTLV-1, Lewy, Parkinson's, Tax
related to Structure · 5
Internexin → Alpha-internexin, III, In Ching, IV, NF-M's
related to Function and expression · 3
Internexin → NF-H, NF-L, NF-M
Alt. symbols · 1
Internexin → NEF5
Domains · 1
Internexin → InterPro
HGNC · 1
Internexin → 6057
Locus · 1
Internexin → Chr. 10 q24
NCBI gene · 1
Internexin → 9118
OMIM · 1
Internexin → 605338
RefSeq · 1
Internexin → NM_032727

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

α-internexin filament intermediate alpha-internexin protein expressed neurofilament central structure also form proteins nervous system neurofilaments filaments axonal rod highly formation

Internexin relationships Subject–Predicate–Object triples

TTTA extracted 32 structured relationships around Internexin. Examples in this analysis include Internexin → Alt. symbols → NEF5 and Internexin → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
InternexinAlt. symbolsNEF51.00infobox
InternexinDomainsInterPro1.00infobox
InternexinHGNC60571.00infobox
InternexinLocusChr. 10 q241.00infobox
InternexinNCBI gene91181.00infobox
InternexinOMIM6053381.00infobox
InternexinRefSeqNM_0327271.00infobox
InternexinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
InternexinStructuresSwiss-model1.00infobox
InternexinSymbolINA1.00infobox
InternexinUniProtQ163521.00infobox
Internexinis abrain and central nervous system filament that is involved in neuronal development and has been suggested to play a role in axonal outgrowth0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Internexin bring nearby vocabulary together. In this analysis, examples include Neurofilaments, Filament and Intermediate. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • intermediate filament
    • Filament
    • Intermediate
    • Filaments
    • Form
    • Internexin
    • Step
    • Formation
    • Neurofilaments
    • Rod
    • Cells
    • Present
    • Α-internexin
  • central nervous system
    • System
    • Nervous
    • Axonal
    • Outgrowth
    • Region
    • Development
    • Domain
    • Protein
    • Rod
    • Α-internexin
    • Cells
    • Neuroblasts
  • rod domain
    • Rod
    • Structure
    • Alpha
    • Region
    • Step
    • Q24
    • Domains
    • Head
    • Nm
    • Formation
    • Highly
    • Form
  • nervous system
    • System
    • Axonal
    • Outgrowth
    • Development
    • Protein
    • Α-internexin
    • Cells
    • Neuroblasts
    • Present
    • Neurons
    • Triplet
    • Neurofilament
  • cerebellar granule cells
    • Present
    • Neurons
    • Triplet
    • Neurofilament
    • Nervous
    • Protein
    • Proteins
    • System
    • Central
    • Expressed
    • Intermediate
    • Filament
  • cells
    • Present
    • Neurons
    • Triplet
    • Neurofilament
    • Nervous
    • Protein
    • Proteins
    • System
    • Central
    • Expressed
    • Intermediate
    • Filament
  • axonal
    • Outgrowth
    • May
    • Development
    • Nervous
    • System
    • Α-internexin
    • Optic
    • Filaments
    • Highly
    • Protein
    • Central
    • Expressed
  • neurofilament
    • Neurons
    • Triplet
    • Proteins
    • Expressed
    • Α-internexin
    • Cells
    • Originally
    • Development
    • Nervous
    • Protein
    • System
    • Central

Connections between topic areas Semantic bridges

For Internexin, one of the stronger structural bridges in this analysis connects Internexin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Internexin — Structure · splits 38 ⟂ 18
Internexin — Function and expression · splits 40 ⟂ 16
Internexin — Disease associations · splits 45 ⟂ 11
Internexin — Overview · splits 46 ⟂ 10

Map overview Semantic statistics

Internexin

Nodes56
Edges55
Triples32
Avg. degree1.96
Density0.035714
Components1

Source & methodology

TTTA analyzes the structure around Internexin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Internexin · EN edition · Analysis: TopicsToTalkAbout

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