Mucin short variant S1

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Explore the main themes, entities and connections around Mucin short variant S1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Role in cancer

Chemotherapeutic drugs Hydrophilic Hydrophobic Growth factors Their receptors

28 related topics

Diagnostic uses

Epitopes Immunohistochemistry Neoplastic Anaplastic large cell lymphoma Cytokeratins

10 related topics

Structure

Glycosylated Phosphoprotein Epithelia Sheddases VNTR

8 related topics

Interactions

Interact CTNND1 ERBB2 GRB2 JUP

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: MUC1, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, mucin 1, cell surface associated, ADTKD2, Ca…
Available structures: Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1SM3, 2ACM
Band: 1q22
Bgee: pylorus · pancreatic ductal cell · nasal epithelium · right uterine tube · cardia
BioGPS: More reference expression data
Chr.: Chromosome 1 (human)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Glycosylated Glycosylation
Phosphoprotein
Epithelia Epithelium
Sheddases Sheddase
VNTR Variable number tandem repeat
Endoplasmic reticulum
Urea
Sodium dodecyl sulfate

Function

Interactions

Interact Protein-protein interaction
CTNND1
ERBB2 HER2/neu
GRB2
JUP Plakoglobin
SOS1

Role in cancer

Chemotherapeutic drugs Chemotherapeutic drug
Hydrophilic
Hydrophobic
Growth factors Growth factor
Their receptors Growth factor receptor
Immune cells Immune cell
Steric hindrance
P53
P21
Apoptosis
Fibroblasts Fibroblast
Akt
Bcl-2-associated death promoter
Bcl-2
Bcl-xL
PI3K
Cytochrome c
Hsp90
Src (gene)
Neuregulin Heregulin
Beta-catenin
LYN
Interleukin 7
PRKCD
GSK3B
Vimentin
CDH2 N-cadherin
Epithelial-mesenchymal transition

Diagnostic uses

As a therapeutic drug target

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes74

Edges73

Triples67

Avg. degree1.97

Density0.027027

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Mucin short variant S1

Top relations

Gene ontology · 27

Mucin short variant S1 → apical plasma membrane, cytokine-mediated signaling pathway, cytoplasm, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, extracellular exosome, extracellular region, extracellular space, Golgi lumen, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of cell adhesion mediated by integrin, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of transcription by competitive promoter binding, nucleus, O-glycan processing, p53 binding, plasma membrane, positive regulation of histone H4 acetylation

Bgee · 10

Mucin short variant S1 → buccal mucosa cell, cardia, gastric mucosa, lower lobe of lung, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, pancreatic ductal cell, pylorus, right uterine tube

RNA expression pattern · 10

Aliases · 1

Mucin short variant S1 → MUC1, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, mucin 1, cell surface associated, ADTKD2, Ca…

Available structures · 1

Mucin short variant S1 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1SM3, 2ACM

Band · 1

Mucin short variant S1 → 1q22

BioGPS · 1

Mucin short variant S1 → More reference expression data

Chr. · 1

Mucin short variant S1 → Chromosome 1 (human)

Databases · 1

Mucin short variant S1 → NCBI: entry; OMA: entry

End · 1

Mucin short variant S1 → 155,192,916 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

muc1 cell cancer domain extracellular surface gene glycosylation protein associated cells breast beta-catenin ca mucin cytoplasmic tail shown human 15-3

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Mucin short variant S1	Aliases	MUC1, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, mucin 1, cell surface associated, ADTKD2, Ca…	1.00	infobox
Mucin short variant S1	Available structures	Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1SM3, 2ACM	1.00	infobox
Mucin short variant S1	Band	1q22	1.00	infobox
Mucin short variant S1	Bgee	pylorus	1.00	infobox
Mucin short variant S1	Bgee	pancreatic ductal cell	1.00	infobox
Mucin short variant S1	Bgee	nasal epithelium	1.00	infobox
Mucin short variant S1	Bgee	right uterine tube	1.00	infobox
Mucin short variant S1	Bgee	cardia	1.00	infobox
Mucin short variant S1	Bgee	olfactory zone of nasal mucosa	1.00	infobox
Mucin short variant S1	Bgee	lower lobe of lung	1.00	infobox
Mucin short variant S1	Bgee	buccal mucosa cell	1.00	infobox
Mucin short variant S1	Bgee	gastric mucosa	1.00	infobox
Mucin short variant S1	Bgee	palpebral conjunctiva	1.00	infobox
Mucin short variant S1	BioGPS	More reference expression data	1.00	infobox
Mucin short variant S1	Chr.	Chromosome 1 (human)	1.00	infobox
Mucin short variant S1	Databases	NCBI: entry; OMA: entry	1.00	infobox
Mucin short variant S1	End	155,192,916 bp	1.00	infobox
Mucin short variant S1	Ensembl	ENSG00000185499	1.00	infobox
Mucin short variant S1	Entrez	4582	1.00	infobox
Mucin short variant S1	External IDs	OMIM: 158340; GeneCards: MUC1	1.00	infobox
Mucin short variant S1	Gene location (Human)	Gene location (Human)Chr.Chromosome 1 (human)Band1q22Start155,185,824 bpEnd155,192,916 bp	1.00	infobox
Mucin short variant S1	Gene ontology	protein binding	1.00	infobox
Mucin short variant S1	Gene ontology	transcription coregulator activity	1.00	infobox
Mucin short variant S1	Gene ontology	RNA polymerase II cis-regulatory region sequence-specific DNA binding	1.00	infobox
Mucin short variant S1	Gene ontology	p53 binding	1.00	infobox
Mucin short variant S1	Gene ontology	extracellular region	1.00	infobox
Mucin short variant S1	Gene ontology	cytoplasm	1.00	infobox
Mucin short variant S1	Gene ontology	integral component of membrane	1.00	infobox
Mucin short variant S1	Gene ontology	nucleus	1.00	infobox
Mucin short variant S1	Gene ontology	Golgi lumen	1.00	infobox

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