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Memantine

Memantine, sold under the brand name Namenda among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. It is taken by mouth.

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3D model (JSmol)
Interactive image · as HCl: Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06DX01 (WHO)
Bioavailability
100%
CAS Number
19982-08-2 Y · as HCl: 41100-52-1
ChEBI
CHEBI:64312 · as HCl: CHEBI:64323

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Overview

Medical uses

Adverse effects

Chemistry

History

Society and culture

Research

Advanced semantic analysis

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Map overview Semantic statistics

Memantine

Nodes185
Edges184
Triples218
Avg. degree1.99
Density0.010811
Components1

How this topic connects Entity context

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Memantine

Top relations

related to Brand names · 115
Memantine → Abixa, Adaxor, Admed, Akatinol, Alceba, Alios, Almenta, Alois, Alzant, Alzer, Alzia, Alzinex, Alzixa, Alzmenda, Alzmex, As, August, Axura, Biomentin, Carrier
related to history · 14
Memantine → Alzheimer's, Axura, By, CNS, Company, Eli Lilly, Germany, However, It, Merz, NMDA, Parkinson's, Prior, The
related to Psychiatric disorders · 7
Memantine → BED, Cochrane, Hedges, However, OCD, PDDs, These
related to Recreational use · 7
Memantine → Even, In, It, NMDA, PCP, Recreational, Reddit
has effect · 6
Memantine → Additionally, Common, Despite, Less, Like, NMDA
related to Parkinson's disease · 6
Memantine → Although, However, Parkinson's, Similarly, The, Whereas
Legal status · 5
Memantine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Alzheimer's disease and dementia · 4
Memantine → AChE, Alzheimer's, One, There
related to Apathy · 4
Memantine → Alzheimer's, Apathy, However, Systematic
3D model (JSmol) · 2
Memantine → as HCl: Interactive image, Interactive image

Important terminology Word statistics

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Important terminology

disease receptor nmda treatment affinity effects alzheimer's drug amantadine however receptors parkinson's antagonist use used may include review ic50 nm

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Memantine3D model (JSmol)Interactive image1.00infobox
Memantine3D model (JSmol)as HCl: Interactive image1.00infobox
MemantineAHFS/Drugs.comMonograph1.00infobox
MemantineATC codeN06DX01 (WHO)1.00infobox
MemantineBioavailability100%1.00infobox
MemantineCAS Number19982-08-2 Y1.00infobox
MemantineCAS Numberas HCl: 41100-52-11.00infobox
MemantineChEBICHEBI:643121.00infobox
MemantineChEBIas HCl: CHEBI:643231.00infobox
MemantineChEMBLChEMBL807 Y1.00infobox
MemantineChEMBLas HCl: ChEMBL16991.00infobox
MemantineChemSpider3914 Y1.00infobox
MemantineChemSpideras HCl: 1578491.00infobox
MemantineCompTox Dashboard (EPA)DTXSID50451741.00infobox
MemantineDrug classNMDA receptor antagonist1.00infobox
MemantineDrugBankDB01043 Y1.00infobox
MemantineDrugBankas HCl: DBSALT0004561.00infobox
MemantineECHA InfoCard100.217.9371.00infobox
MemantineElimination half-life60–80 hours1.00infobox
MemantineExcretionUrine (57–82% unchanged)1.00infobox
MemantineFormulaC12H21N1.00infobox
MemantineIUPHAR/BPS42531.00infobox
MemantineKEGGD08174 Y1.00infobox
MemantineKEGGas HCl: D049051.00infobox
MemantineLegal statusAU: S4 (Prescription only)1.00infobox
MemantineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
MemantineLegal statusUK: POM (Prescription only)1.00infobox
MemantineLegal statusUS: ℞-only1.00infobox
MemantineLegal statusEU: Rx-only1.00infobox
MemantineLicense dataUS DailyMed: Memantine1.00infobox

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