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The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG). As the name indicates, this receptor interacts with interleukin-2, a pleiotropic cytokine which plays an…
The analysis highlights Expression, Signalling cascade of interleukin-2 receptor and Clinical significance as prominent areas in the source structure around IL2RA.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around IL2RA shows recurring relationship patterns in the source. For example, IL2RA → activation-induced cell death of T cells, apoptotic process, cell population proliferation, cell surface, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, external side of plasma membrane, immune response, immune system process, inflammatory response, inflammatory response to antigenic stimulus, integral component of membrane, interleukin-2 binding, interleukin-2 receptor activity, interleukin-2 receptor complex, interleukin-2-mediated signaling pathway, intracellular anatomical structure, MAPK cascade, membrane, negative regulation of defense response to virus Another extracted example is IL2RA → Also, C-terminus, CD122, CD132, CD25, Homodimeric, However, IL-15, IL-2, IL-21, IL-4, IL-7, IL-9, IL2, IL2RB, IL2RG, Interleukin-2, Kd, Moreover, N-terminus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
receptor interleukin-2 cells cd25 protein gene human alpha il-2 subunit immune bp signalling 10 regulatory chr band expression levels also
TTTA extracted 159 structured relationships around IL2RA. Examples in this analysis include IL2RA → Aliases → IL2RA, CD25, IDDM10, IL2R, TCGFR, p55, IMD41, interleukin 2 receptor subunit alpha and IL2RA → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Z92, 2B5I, 2ERJ, 3IU3, 3NFP. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IL2RA | Aliases | IL2RA, CD25, IDDM10, IL2R, TCGFR, p55, IMD41, interleukin 2 receptor subunit alpha | 1.00 | infobox |
| IL2RA | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Z92, 2B5I, 2ERJ, 3IU3, 3NFP | 1.00 | infobox |
| IL2RA | Band | 10p15.1 | 1.00 | infobox |
| IL2RA | Band | 2 A1|2 8.91 cM | 1.00 | infobox |
| IL2RA | Bgee | lymph node | 1.00 | infobox |
| IL2RA | Bgee | appendix | 1.00 | infobox |
| IL2RA | Bgee | spleen | 1.00 | infobox |
| IL2RA | Bgee | buccal mucosa cell | 1.00 | infobox |
| IL2RA | Bgee | gallbladder | 1.00 | infobox |
| IL2RA | Bgee | blood | 1.00 | infobox |
| IL2RA | Bgee | granulocyte | 1.00 | infobox |
| IL2RA | Bgee | epithelium of colon | 1.00 | infobox |
| IL2RA | Bgee | smooth muscle tissue | 1.00 | infobox |
| IL2RA | Bgee | tonsil | 1.00 | infobox |
| IL2RA | Bgee | thymus | 1.00 | infobox |
| IL2RA | Bgee | zygote | 1.00 | infobox |
| IL2RA | Bgee | secondary oocyte | 1.00 | infobox |
| IL2RA | Bgee | muscle of thigh | 1.00 | infobox |
| IL2RA | Bgee | primary oocyte | 1.00 | infobox |
| IL2RA | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| IL2RA | Bgee | esophagus | 1.00 | infobox |
| IL2RA | BioGPS | More reference expression data | 1.00 | infobox |
| IL2RA | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| IL2RA | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| IL2RA | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IL2RA | End | 6,062,370 bp | 1.00 | infobox |
| IL2RA | End | 11,698,004 bp | 1.00 | infobox |
| IL2RA | Ensembl | ENSG00000134460 | 1.00 | infobox |
| IL2RA | Entrez | 3559 | 1.00 | infobox |
| IL2RA | External IDs | OMIM: 147730; MGI: 96549; GeneCards: IL2RA | 1.00 | infobox |
The concept neighborhoods around IL2RA bring nearby vocabulary together. In this analysis, examples include Receptor, Gene and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IL2RA, one of the stronger structural bridges in this analysis connects IL2RA with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IL2RA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Expression, Signalling cascade of interleukin-2 receptor & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IL2RA · EN edition · Analysis: TopicsToTalkAbout