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Leukemia

Leukemia (also spelled leukaemia; pronounced /luːˈkiːmiːə/ loo-KEE-mee-ə) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Signs and symptoms may include bleeding and bruising, bone pain, fatigue, fever…

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Causes
Inherited and environmental factors
Deaths
353,500 (2015)
Diagnostic method
Blood tests, bone marrow biopsy
Frequency
2.3 million (2015)
Other names
Leukaemia
Prognosis
Five-year survival rate 69% (U.S.)

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Overview

Classification

Signs and symptoms

Causes

Diagnosis

Treatment

Prognosis

Epidemiology

History

Society and culture

Research directions

Pregnancy

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Leukemia

Nodes241
Edges240
Triples213
Avg. degree1.99
Density0.008299
Components1

How this topic connects Entity context

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Leukemia

Top relations

related to Specific types · 43
Leukemia → About, Acute, Adult T-cell, ALL, AML, B-cell, Burkitt's, CD4, Chronic, CLL, Clonal, CML, Despite, Europe, Gleevec, Glivec, Hairy, HCL, HIV, HTLV
related to Acute lymphoblastic · 16
Leukemia → Additionally, ALL, Alternatively, CNS, Consolidation, For, High-risk, In, Induction, L-asparaginase, Maintenance, Management, MP, People, Standard, There
related to history · 13
Leukemia → Alfred-Armand-Louis-Marie Velpeau, ALL, Around, Boston, By, Franz Ernst Christian Neumann, Neumann, Nevertheless, Rudolf Virchow, Sidney Farber, The, This, Virchow's
related to Non-ionizing radiation · 10
Leukemia → Cancer, ELF, ELFs, No, Research, Since, The International Agency, They, Whether, World Health Organization
related to Pre-leukemia · 10
Leukemia → B-cell, Clonal, Down, International Prognostic Scoring System, IPSS, MDS, Monoclonal B-cell, Once MDS, The, Transient
related to United States · 10
Leukemia → About, American, Among, Approximately, Boys, Only, Rates, This, United States, US
related to Genetic conditions · 9
Leukemia → Down, Family, Fanconi, For, In, Mutation, Some, SPRED1, The
related to Diagnosis · 8
Leukemia → CT, Diagnosis, Following, MRI, Sometimes, These, When, X-ray
related to Research directions · 8
Leukemia → By, Clinical/translational, DNA, Hundreds, In, Significant, Studies, The
related to T-cell prolymphocytic · 8
Leukemia → Alemtuzumab, Campath, CHOP, COP, Many, Most, T-cell, VAPEC-B

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Important terminology

people treatment blood acute cells bone marrow may chemotherapy disease children chronic common cell cancer risk myeloid also radiation survival

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LeukemiaCausesInherited and environmental factors1.00infobox
LeukemiaDeaths353,500 (2015)1.00infobox
LeukemiaDiagnostic methodBlood tests, bone marrow biopsy1.00infobox
LeukemiaFrequency2.3 million (2015)1.00infobox
LeukemiaOther namesLeukaemia1.00infobox
LeukemiaPrognosisFive-year survival rate 69% (U.S.)1.00infobox
LeukemiaPronunciation/luːˈkiːmiːə/1.00infobox
LeukemiaRisk factorsSmoking, family history, ionizing radiation, some chemicals such as trichloroethylene, prior chemotherapy, Down syndrome.1.00infobox
LeukemiaSpecialtyHematology and oncology1.00infobox
LeukemiaSymptomsBleeding, bruising, fatigue, fever, increased risk of infections1.00infobox
LeukemiaTreatmentChemotherapy, radiation therapy, targeted therapy, bone marrow transplant, supportive care1.00infobox
LeukemiaUsual onsetAll ages, most common in 60s and 70s. It is the most common malignant cancer in children, but the cure rates are also higher for them.1.00infobox
Leukemiais apre-leukemic condition.Clonal hematopoiesis is a common age-related phenomenon with a low risk of progression to myelodysplastic syndrome0.90text
Leukemiais asecond most common form of cancer in infants0.90text
Leukemiais aeleventh most common cancer0.90text
Leukemiais aeleventh most common cancer in the UK0.90text

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