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IL2RB

Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene. Also known as CD122; IL15RB; P70-75.

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Function

5 related topics

Interactions

5 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS7
Band
22q12.3 · 15 E1|15 37.52 cM
Bgee
granulocyte · decidua · mucosa of ileum · blood · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

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Overview

Function

Interactions

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Map overview Semantic statistics

IL2RB

Nodes16
Edges15
Triples87
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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IL2RB

Top relations

Gene ontology · 24
IL2RB → cell surface, cytokine receptor activity, cytokine-mediated signaling pathway, cytosol, endosome, external side of plasma membrane, integral component of membrane, integral component of plasma membrane, interleukin-15 receptor activity, interleukin-15-mediated signaling pathway, interleukin-2 binding, interleukin-2 receptor activity, interleukin-2 receptor complex, interleukin-2-mediated signaling pathway, MAPK cascade, membrane, negative regulation of apoptotic process, plasma membrane, positive regulation of phagocytosis, protein binding
Bgee · 17
IL2RB → appendix, blood, bone marrow cell, decidua, epithelium of nasopharynx, gastrula, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, mucosa of ileum, mucosa of urinary bladder, pharynx, secondary oocyte, spleen, thymus, zygote
RNA expression pattern · 17
IL2RB → appendix, blood, bone marrow cell, decidua, epithelium of nasopharynx, gastrula, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, mucosa of ileum, mucosa of urinary bladder, pharynx, secondary oocyte, spleen, thymus, zygote
related to Clinical significance · 3
IL2RB → IL-15, IL2RB-mediated, Increased IL-15
related to Interactions · 3
IL2RB → CISH, HGS, Janus
Band · 2
IL2RB → 15 E1|15 37.52 cM, 22q12.3
Chr. · 2
IL2RB → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
IL2RB → 37,175,054 bp, 78,379,471 bp
Aliases · 1
IL2RB → IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
Available structures · 1
IL2RB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS7

Important terminology Word statistics

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Important terminology

receptor bp gene chr human band subunit chromosome 22 protein also beta location il-15 mouse interleukin signaling transduction interleukin-2 cd122

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
IL2RBAliasesIL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD631.00infobox
IL2RBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS71.00infobox
IL2RBBand22q12.31.00infobox
IL2RBBand15 E1|15 37.52 cM1.00infobox
IL2RBBgeegranulocyte1.00infobox
IL2RBBgeedecidua1.00infobox
IL2RBBgeemucosa of ileum1.00infobox
IL2RBBgeeblood1.00infobox
IL2RBBgeelymph node1.00infobox
IL2RBBgeespleen1.00infobox
IL2RBBgeeappendix1.00infobox
IL2RBBgeebone marrow cell1.00infobox
IL2RBBgeemucosa of urinary bladder1.00infobox
IL2RBBgeeepithelium of nasopharynx1.00infobox
IL2RBBgeemesenteric lymph nodes1.00infobox
IL2RBBgeesecondary oocyte1.00infobox
IL2RBBgeegastrula1.00infobox
IL2RBBgeezygote1.00infobox
IL2RBBgeethymus1.00infobox
IL2RBBgeepharynx1.00infobox
IL2RBBgeelumbar subsegment of spinal cord1.00infobox
IL2RBBioGPSMore reference expression data1.00infobox
IL2RBChr.Chromosome 22 (human)1.00infobox
IL2RBChr.Chromosome 15 (mouse)1.00infobox
IL2RBDatabasesNCBI: entry; OMA: entry1.00infobox
IL2RBEnd37,175,054 bp1.00infobox
IL2RBEnd78,379,471 bp1.00infobox
IL2RBEnsemblENSG000001003851.00infobox
IL2RBEntrez35601.00infobox
IL2RBExternal IDsOMIM: 146710; MGI: 96550; GeneCards: IL2RB1.00infobox

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