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IL2RB: Measurement, Function & Interactions

Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene. Also known as CD122; IL15RB; P70-75.

Language: English [EN]
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IL2RB topic overview

The analysis highlights Measurement, Function and Interactions as prominent areas in the source structure around IL2RB.

Related topics
12
Source areas
3
Connected nodes
15
Extracted relationships
87
Concept neighborhoods
7
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Interactions · 5 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS7
Band
22q12.3 · 15 E1|15 37.52 cM
Bgee
granulocyte · decidua · mucosa of ileum · blood · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IL2RB connects Entity context

The extracted context around IL2RB shows recurring relationship patterns in the source. For example, IL2RB → cell surface, cytokine receptor activity, cytokine-mediated signaling pathway, cytosol, endosome, external side of plasma membrane, integral component of membrane, integral component of plasma membrane, interleukin-15 receptor activity, interleukin-15-mediated signaling pathway, interleukin-2 binding, interleukin-2 receptor activity, interleukin-2 receptor complex, interleukin-2-mediated signaling pathway, MAPK cascade, membrane, negative regulation of apoptotic process, plasma membrane, positive regulation of phagocytosis, protein binding Another extracted example is IL2RB → appendix, blood, bone marrow cell, decidua, epithelium of nasopharynx, gastrula, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, mucosa of ileum, mucosa of urinary bladder, pharynx, secondary oocyte, spleen, thymus, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

IL2RB

Top relations

Gene ontology · 24
IL2RB → cell surface, cytokine receptor activity, cytokine-mediated signaling pathway, cytosol, endosome, external side of plasma membrane, integral component of membrane, integral component of plasma membrane, interleukin-15 receptor activity, interleukin-15-mediated signaling pathway, interleukin-2 binding, interleukin-2 receptor activity, interleukin-2 receptor complex, interleukin-2-mediated signaling pathway, MAPK cascade, membrane, negative regulation of apoptotic process, plasma membrane, positive regulation of phagocytosis, protein binding
Bgee · 17
IL2RB → appendix, blood, bone marrow cell, decidua, epithelium of nasopharynx, gastrula, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, mucosa of ileum, mucosa of urinary bladder, pharynx, secondary oocyte, spleen, thymus, zygote
RNA expression pattern · 17
IL2RB → appendix, blood, bone marrow cell, decidua, epithelium of nasopharynx, gastrula, granulocyte, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, mucosa of ileum, mucosa of urinary bladder, pharynx, secondary oocyte, spleen, thymus, zygote
related to Clinical significance · 3
IL2RB → IL-15, IL2RB-mediated, Increased IL-15
related to Interactions · 3
IL2RB → CISH, HGS, Janus
Band · 2
IL2RB → 15 E1|15 37.52 cM, 22q12.3
Chr. · 2
IL2RB → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
IL2RB → 37,175,054 bp, 78,379,471 bp
Aliases · 1
IL2RB → IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
Available structures · 1
IL2RB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS7

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor bp gene chr human band subunit chromosome 22 protein also beta location il-15 mouse interleukin signaling transduction interleukin-2 cd122

IL2RB relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around IL2RB. Examples in this analysis include IL2RB → Aliases → IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63 and IL2RB → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS7. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IL2RBAliasesIL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD631.00infobox
IL2RBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2B5I, 2ERJ, 3QAZ, 4GS71.00infobox
IL2RBBand22q12.31.00infobox
IL2RBBand15 E1|15 37.52 cM1.00infobox
IL2RBBgeegranulocyte1.00infobox
IL2RBBgeedecidua1.00infobox
IL2RBBgeemucosa of ileum1.00infobox
IL2RBBgeeblood1.00infobox
IL2RBBgeelymph node1.00infobox
IL2RBBgeespleen1.00infobox
IL2RBBgeeappendix1.00infobox
IL2RBBgeebone marrow cell1.00infobox
IL2RBBgeemucosa of urinary bladder1.00infobox
IL2RBBgeeepithelium of nasopharynx1.00infobox
IL2RBBgeemesenteric lymph nodes1.00infobox
IL2RBBgeesecondary oocyte1.00infobox
IL2RBBgeegastrula1.00infobox
IL2RBBgeezygote1.00infobox
IL2RBBgeethymus1.00infobox
IL2RBBgeepharynx1.00infobox
IL2RBBgeelumbar subsegment of spinal cord1.00infobox
IL2RBBioGPSMore reference expression data1.00infobox
IL2RBChr.Chromosome 22 (human)1.00infobox
IL2RBChr.Chromosome 15 (mouse)1.00infobox
IL2RBDatabasesNCBI: entry; OMA: entry1.00infobox
IL2RBEnd37,175,054 bp1.00infobox
IL2RBEnd78,379,471 bp1.00infobox
IL2RBEnsemblENSG000001003851.00infobox
IL2RBEntrez35601.00infobox
IL2RBExternal IDsOMIM: 146710; MGI: 96550; GeneCards: IL2RB1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IL2RB bring nearby vocabulary together. In this analysis, examples include External, Function and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IL2RB
    • External
    • Function
    • Gene
    • Interleukin-2
    • Search
    • Interleukin
    • Location
    • Receptor
    • Chromosome
    • Human
    • Protein
    • Bp
  • il2rb
    • External
    • Function
    • Gene
    • Interleukin-2
    • Search
    • Interleukin
    • Location
    • Receptor
    • Chromosome
    • Human
    • Protein
    • Bp
  • gene
    • Location
    • Chromosome
    • Human
    • Il2rb
    • Protein
    • Bp
    • Chr
    • Subunit
    • E1
    • End
    • External
    • Function
  • il-15 receptor
    • Forms
    • Interleukin
    • Signaling
    • Protein
    • External
    • Function
    • Search
    • Involved
    • Location
    • Transduction
    • Also
    • Chromosome
  • function
    • External
    • Search
    • Interleukin
    • Location
    • Chromosome
    • Human
    • Il2rb
    • Bp
    • Chr
    • Gene
    • E1
    • End
  • protein
    • Membrane
    • Forms
    • Receptor
    • Subunit
    • E1
    • End
    • External
    • Function
    • Mouse
    • Search
    • Interleukin
    • Involved
  • interleukin 2
    • Search
    • Forms
    • Involved
    • Location
    • Transduction
    • Receptor
    • E1
    • End
    • Interleukin-2
    • Membrane
    • Mouse
    • P70-75

Connections between topic areas Semantic bridges

For IL2RB, one of the stronger structural bridges in this analysis connects IL2RB with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IL2RBFunction · splits 10 ⟂ 6
IL2RBInteractions · splits 10 ⟂ 6
IL2RBOverview · splits 13 ⟂ 3

Map overview Semantic statistics

IL2RB

Nodes16
Edges15
Triples87
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around IL2RB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IL2RB · EN edition · Analysis: TopicsToTalkAbout

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