IL1RL1

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Explore the main themes, entities and connections around IL1RL1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Regulatory T cells

IL-33 Keratinocytes IFNg IL-1 Isoforms

12 related topics

Function

Toll-like receptor NF-κB MAP kinases Interleukin-33

4 related topics

Molecular biology

MyD88 IRAK1 IRAK4 TRAF6

4 related topics

Clinical significance

Atopic dermatitis Asthma Cardiac biomarker

3 related topics

Key facts & relationships

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3.2.2.6: ↗
Aliases: IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1, interleukin 1 receptor like 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KC3
Band: 2q12.1 · 1 B|1 19.19 cM
Bgee: upper lobe of left lung · decidua · right lung · cartilage tissue · lower lobe of lung
BioGPS: More reference expression data

Topics to explore

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Overview

Function

Molecular biology

Regulatory T cells

IL-33
Keratinocytes
IFNg
IL-1 Interleukin 1
Isoforms
T regulatory cells T regulatory cells?action=edit&redlink=1
IL-1R
Th2
GATA3
Foxp3
IL-23 Interleukin 23
STAT3

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes31

Edges30

Triples120

Avg. degree1.94

Density0.064516

Components1

How this topic connects Entity context

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IL1RL1

Top relations

Bgee · 20

IL1RL1 → body of stomach, cartilage tissue, decidua, duodenum, embryo, endothelial cell of lymphatic vessel, esophagus, granulocyte, human kidney, ileum, jejunum, lactiferous gland, left adrenal cortex, left adrenal gland, lip, lower lobe of lung, muscle of thigh, right adrenal gland, right lung, upper lobe of left lung

Gene ontology · 20

IL1RL1 → cytokine receptor activity, external side of plasma membrane, extracellular matrix, extracellular region, immune response, integral component of membrane, interleukin-1 receptor activity, interleukin-33 binding, interleukin-33 receptor activity, interleukin-33-mediated signaling pathway, membrane, negative regulation of I-kappaB kinase/NF-kappaB signaling, negative regulation of interferon-gamma production, negative regulation of T-helper 1 type immune response, plasma membrane, positive regulation of inflammatory response, positive regulation of interleukin-5 production, positive regulation of macrophage activation, protein binding, signal transduction

RNA expression pattern · 20

related to Regulatory T cells · 19

IL1RL1 → Activation, Alarmin IL-33, Human, IFNg, IL-1, Il-33, IL-33/ST2, IL1RAcP, In, Interestingly, MyD88, Releasing, ST2, The, This, TIR, Toll/IL-1, TRAF6, Two

related to Function · 15

IL1RL1 → As, Binding, IL-33, Interleukin-33, MAP, NF-κB, ST2, ST2L, The, The ST2, This, TIR, Toll-like, Unlike, When

Band · 2

IL1RL1 → 1 B|1 19.19 cM, 2q12.1

Chr. · 2

IL1RL1 → Chromosome 1 (mouse), Chromosome 2 (human)

End · 2

IL1RL1 → 102,352,037 bp, 40,504,575 bp

3.2.2.6 · 1

IL1RL1 → ↗

Aliases · 1

IL1RL1 → IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1, interleukin 1 receptor like 1

Important terminology Word statistics

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Important terminology

st2 il-33 gene receptor function protein soluble bp regulatory cells human activation chr band chromosome il-1 expression cell cytokine also

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
IL1RL1	3.2.2.6	↗	1.00	infobox
IL1RL1	Aliases	IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1, interleukin 1 receptor like 1	1.00	infobox
IL1RL1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KC3	1.00	infobox
IL1RL1	Band	2q12.1	1.00	infobox
IL1RL1	Band	1 B\|1 19.19 cM	1.00	infobox
IL1RL1	Bgee	upper lobe of left lung	1.00	infobox
IL1RL1	Bgee	decidua	1.00	infobox
IL1RL1	Bgee	right lung	1.00	infobox
IL1RL1	Bgee	cartilage tissue	1.00	infobox
IL1RL1	Bgee	lower lobe of lung	1.00	infobox
IL1RL1	Bgee	left adrenal gland	1.00	infobox
IL1RL1	Bgee	left adrenal cortex	1.00	infobox
IL1RL1	Bgee	right adrenal gland	1.00	infobox
IL1RL1	Bgee	human kidney	1.00	infobox
IL1RL1	Bgee	body of stomach	1.00	infobox
IL1RL1	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
IL1RL1	Bgee	granulocyte	1.00	infobox
IL1RL1	Bgee	embryo	1.00	infobox
IL1RL1	Bgee	duodenum	1.00	infobox
IL1RL1	Bgee	lip	1.00	infobox
IL1RL1	Bgee	ileum	1.00	infobox
IL1RL1	Bgee	jejunum	1.00	infobox
IL1RL1	Bgee	muscle of thigh	1.00	infobox
IL1RL1	Bgee	esophagus	1.00	infobox
IL1RL1	Bgee	lactiferous gland	1.00	infobox
IL1RL1	BioGPS	More reference expression data	1.00	infobox
IL1RL1	Chr.	Chromosome 2 (human)	1.00	infobox
IL1RL1	Chr.	Chromosome 1 (mouse)	1.00	infobox
IL1RL1	Databases	NCBI: entry; OMA: entry	1.00	infobox
IL1RL1	End	102,352,037 bp	1.00	infobox

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