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Bcl-2 homologous antagonist/killer is a protein which in humans is encoded by the BAK1 gene on chromosome 6. It belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and…
The analysis highlights Interactions, Clinical significance and Function as prominent areas in the source structure around Bcl-2 homologous antagonist killer.
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The extracted context around Bcl-2 homologous antagonist killer shows recurring relationship patterns in the source. For example, Bcl-2 homologous antagonist killer → activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, ageing, animal organ regeneration, apoptotic process, apoptotic process involved in blood vessel morphogenesis, apoptotic signaling pathway, B cell apoptotic process, B cell homeostasis, B cell negative selection, BAK complex, BH domain binding, blood vessel remodeling, brain development, cell population proliferation, cellular response to mechanical stimulus, cellular response to UV, chaperone binding, cytosol Another extracted example is Bcl-2 homologous antagonist killer → apex of heart, duodenum, granulocyte, left adrenal cortex, left adrenal gland, monocyte, mucosa of transverse colon, rectum, right adrenal cortex, right adrenal gland. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bak1 protein gene chromosome bcl2 human bcl-2 pro-apoptotic family mitochondria membrane involved mitochondrial bp form bak cells cellular release cytochrome
TTTA extracted 117 structured relationships around Bcl-2 homologous antagonist killer. Examples in this analysis include Bcl-2 homologous antagonist killer → Aliases → BAK1, BAK, BAK-LIKE, BCL2L7, CDN1, BCL2 antagonist/killer 1 and Bcl-2 homologous antagonist killer → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5AJK, 1BXL, 2IMS, 2IMT, 2JBY, 2JCN, 2LP8, 2M5B, 2XPX, 3I1H, 3QBR, 4D2L, 4U2U, 4U2V, 4UF1, 5FMK, 5FMI. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Bcl-2 homologous antagonist killer | Aliases | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1, BCL2 antagonist/killer 1 | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5AJK, 1BXL, 2IMS, 2IMT, 2JBY, 2JCN, 2LP8, 2M5B, 2XPX, 3I1H, 3QBR, 4D2L, 4U2U, 4U2V, 4UF1, 5FMK, 5FMI | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Band | 6p21.31 | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | mucosa of transverse colon | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | granulocyte | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | left adrenal gland | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | left adrenal cortex | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | right adrenal gland | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | monocyte | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | apex of heart | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | duodenum | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | right adrenal cortex | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Bgee | rectum | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | BioGPS | More reference expression data | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | End | 33,580,293 bp | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Ensembl | ENSG00000030110 | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Entrez | 578 | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | External IDs | OMIM: 600516; MGI: 1097161; GeneCards: BAK1 | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene location (Human) | Gene location (Human)Chr.Chromosome 6 (human)Band6p21.31Start33,572,547 bpEnd33,580,293 bp | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | transmembrane transporter binding | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | metal ion binding | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | protein binding | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | identical protein binding | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | protein homodimerization activity | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | molecular function | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | heat shock protein binding | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | protein heterodimerization activity | 1.00 | infobox |
| Bcl-2 homologous antagonist killer | Gene ontology | chaperone binding | 1.00 | infobox |
The concept neighborhoods around Bcl-2 homologous antagonist killer bring nearby vocabulary together. In this analysis, examples include External, Chromosome and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Bcl-2 homologous antagonist killer, one of the stronger structural bridges in this analysis connects Bcl-2 homologous antagonist killer with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Bcl-2 homologous antagonist killer to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical significance & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Bcl-2 homologous antagonist killer · EN edition · Analysis: TopicsToTalkAbout