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Fas receptor

The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is encoded by the FAS gene. Fas was first identified using a monoclonal antibody generated by immunizing mice with the FS-7 cell line. Thus, the…

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Aliases
FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DDF, 3EWT, 3EZQ, 3THM, 3TJE, 2NA7
Band
10q23.31 · 19 C1|19 29.48 cM
Bgee
rectum · left ovary · right ovary · gallbladder · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)

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Overview

Gene

Protein

Function

Role in apoptosis

Interactions

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Map overview Semantic statistics

Fas receptor

Nodes54
Edges53
Triples162
Avg. degree1.96
Density0.037037
Components1

How this topic connects Entity context

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Fas receptor

Top relations

Gene ontology · 76
Fas receptor → activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, activation-induced cell death of T cells, apoptotic process, apoptotic signaling pathway, B cell mediated immunity, calmodulin binding, CD95 death-inducing signaling complex, cell surface, cellular response to amino acid starvation, cellular response to hyperoxia, cellular response to lithium ion, cellular response to mechanical stimulus, circadian rhythm, cytosol, death-inducing signaling complex, external side of plasma membrane, extracellular exosome, extracellular region, extrinsic apoptotic signaling pathway
Bgee · 20
Fas receptor → brown adipose tissue, duodenum, epithelium of nasopharynx, gallbladder, granulocyte, intercostal muscle, jejunum, left adrenal cortex, left adrenal gland, left ovary, rectum, right adrenal cortex, right lung, right lung lobe, right ovary, seminal vesicula, stromal cell of endometrium, thymus, tunica media of zone of aorta, white adipose tissue
RNA expression pattern · 20
Fas receptor → brown adipose tissue, duodenum, epithelium of nasopharynx, gallbladder, granulocyte, intercostal muscle, jejunum, left adrenal cortex, left adrenal gland, left ovary, rectum, right adrenal cortex, right lung, right lung lobe, right ovary, seminal vesicula, stromal cell of endometrium, thymus, tunica media of zone of aorta, white adipose tissue
related to Protein · 10
Fas receptor → Apoptosis-inducing Fas, Exon, Exons, Fas, However, Many, Previous, RNA, The, TIA1
related to Interactions · 5
Fas receptor → Caspase, CFLAR, FADD, Fas, PDCD6
related to Gene · 4
Fas receptor → FAS, Similar, The, Watson
Band · 2
Fas receptor → 10q23.31, 19 C1|19 29.48 cM
Chr. · 2
Fas receptor → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
Fas receptor → 34,327,772 bp, 89,029,605 bp
Aliases · 1
Fas receptor → FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Important terminology Word statistics

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Important terminology

fas apoptosis receptor cell protein tumor cells gene human death bp 10 surface ligand chr band chromosome mouse domain also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fas receptorAliasesFAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor1.00infobox
Fas receptorAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1DDF, 3EWT, 3EZQ, 3THM, 3TJE, 2NA71.00infobox
Fas receptorBand10q23.311.00infobox
Fas receptorBand19 C1|19 29.48 cM1.00infobox
Fas receptorBgeerectum1.00infobox
Fas receptorBgeeleft ovary1.00infobox
Fas receptorBgeeright ovary1.00infobox
Fas receptorBgeegallbladder1.00infobox
Fas receptorBgeeepithelium of nasopharynx1.00infobox
Fas receptorBgeeright lung1.00infobox
Fas receptorBgeeleft adrenal gland1.00infobox
Fas receptorBgeestromal cell of endometrium1.00infobox
Fas receptorBgeeright adrenal cortex1.00infobox
Fas receptorBgeeleft adrenal cortex1.00infobox
Fas receptorBgeegranulocyte1.00infobox
Fas receptorBgeethymus1.00infobox
Fas receptorBgeeright lung lobe1.00infobox
Fas receptorBgeetunica media of zone of aorta1.00infobox
Fas receptorBgeeseminal vesicula1.00infobox
Fas receptorBgeeintercostal muscle1.00infobox
Fas receptorBgeeduodenum1.00infobox
Fas receptorBgeejejunum1.00infobox
Fas receptorBgeebrown adipose tissue1.00infobox
Fas receptorBgeewhite adipose tissue1.00infobox
Fas receptorBioGPSMore reference expression data1.00infobox
Fas receptorChr.Chromosome 10 (human)1.00infobox
Fas receptorChr.Chromosome 19 (mouse)1.00infobox
Fas receptorDatabasesNCBI: entry; OMA: entry1.00infobox
Fas receptorEnd89,029,605 bp1.00infobox
Fas receptorEnd34,327,772 bp1.00infobox

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