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CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and integrin αIIbβ3.…
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Explore the main themes, entities and connections around CD154. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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cells cd40 cell cd40l human bp gene chr band activated activation surface antibody expression endothelial also called tfh chromosome protein
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD154 | Aliases | CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L, CD40 ligand | 1.00 | infobox |
| CD154 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ALY, 1I9R, 3LKJ, 3QD6 | 1.00 | infobox |
| CD154 | Band | Xq26.3 | 1.00 | infobox |
| CD154 | Band | X A6|X 31.21 cM | 1.00 | infobox |
| CD154 | Bgee | granulocyte | 1.00 | infobox |
| CD154 | Bgee | lymph node | 1.00 | infobox |
| CD154 | Bgee | blood | 1.00 | infobox |
| CD154 | Bgee | appendix | 1.00 | infobox |
| CD154 | Bgee | rectum | 1.00 | infobox |
| CD154 | Bgee | spleen | 1.00 | infobox |
| CD154 | Bgee | gallbladder | 1.00 | infobox |
| CD154 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| CD154 | Bgee | bone marrow | 1.00 | infobox |
| CD154 | Bgee | epithelium of colon | 1.00 | infobox |
| CD154 | Bgee | thymus | 1.00 | infobox |
| CD154 | Bgee | Meckel's cartilage | 1.00 | infobox |
| CD154 | Bgee | hip | 1.00 | infobox |
| CD154 | Bgee | bones of pectoral girdle | 1.00 | infobox |
| CD154 | Bgee | shoulder | 1.00 | infobox |
| CD154 | Bgee | humerus | 1.00 | infobox |
| CD154 | Bgee | right kidney | 1.00 | infobox |
| CD154 | Bgee | scapula | 1.00 | infobox |
| CD154 | Bgee | jejunum | 1.00 | infobox |
| CD154 | BioGPS | More reference expression data | 1.00 | infobox |
| CD154 | Chr. | X chromosome (human) | 1.00 | infobox |
| CD154 | Chr. | X chromosome (mouse) | 1.00 | infobox |
| CD154 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD154 | End | 136,660,390 bp | 1.00 | infobox |
| CD154 | End | 56,269,402 bp | 1.00 | infobox |
| CD154 | Ensembl | ENSG00000102245 | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.