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TRAF3

TNF receptor-associated factor (TRAF3) is a protein that in humans is encoded by the TRAF3 gene.

Interactions, Clinical significance & Function

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Interactions

9 related topics

Clinical significance

3 related topics

Function

1 related topics

Overview

3 related topics

Key facts & relationships

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2.3.2.27
Aliases
TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, TNF receptor associated factor 3, RNF118
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FLK, 1FLL, 1KZZ, 1L0A, 1RF3, 1ZMS, 2ECY, 2GKW
Band
14q32.32 · 12 F1|12 60.94 cM
Bgee
cartilage tissue · monocyte · Brodmann area 46 · appendix · middle temporal gyrus
BioGPS
More reference expression data

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Overview

Function

Interactions

Clinical significance

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Map overview Semantic statistics

TRAF3

Nodes21
Edges20
Triples106
Avg. degree1.9
Density0.095238
Components1

How this topic connects Entity context

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TRAF3

Top relations

Gene ontology · 34
TRAF3 → apoptotic process, CD40 receptor complex, cytoplasm, cytoplasmic side of plasma membrane, cytosol, endosome, immune system process, innate immune response, metal ion binding, mitochondrion, negative regulation of NF-kappaB transcription factor activity, protein binding, protein deubiquitination, protein kinase binding, protein phosphatase binding, protein ubiquitination, protein-containing complex, regulation of apoptotic process, regulation of cytokine production, regulation of defense response to virus
Bgee · 20
TRAF3 → appendix, Brodmann area 46, CA3 field, cartilage tissue, central gray substance of midbrain, dorsomedial hypothalamic nucleus, entorhinal cortex, Epithelium of choroid plexus, granulocyte, lacrimal gland, lymph node, middle temporal gyrus, monocyte, postcentral gyrus, subiculum, superior colliculus, testicle, tibia, ventral tegmental area, vestibular sensory epithelium
RNA expression pattern · 20
TRAF3 → appendix, Brodmann area 46, CA3 field, cartilage tissue, central gray substance of midbrain, dorsomedial hypothalamic nucleus, entorhinal cortex, Epithelium of choroid plexus, granulocyte, lacrimal gland, lymph node, middle temporal gyrus, monocyte, postcentral gyrus, subiculum, superior colliculus, testicle, tibia, ventral tegmental area, vestibular sensory epithelium
related to Interactions · 6
TRAF3 → Caspase, CD27, CD40, Nucleoporin, RANK, TANK
Band · 2
TRAF3 → 12 F1|12 60.94 cM, 14q32.32
Chr. · 2
TRAF3 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
TRAF3 → 102,911,500 bp, 111,233,587 bp
2.3.2.27 · 1
TRAF3 → ↗
Aliases · 1
TRAF3 → TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, TNF receptor associated factor 3, RNF118
Available structures · 1
TRAF3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FLK, 1FLL, 1KZZ, 1L0A, 1RF3, 1ZMS, 2ECY, 2GKW

Important terminology Word statistics

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Important terminology

bp gene chr human band receptor protein factor chromosome 14 tnf location cd40 traf mouse associated signal transduction function family

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TRAF32.3.2.271.00infobox
TRAF3AliasesTRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, TNF receptor associated factor 3, RNF1181.00infobox
TRAF3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FLK, 1FLL, 1KZZ, 1L0A, 1RF3, 1ZMS, 2ECY, 2GKW1.00infobox
TRAF3Band14q32.321.00infobox
TRAF3Band12 F1|12 60.94 cM1.00infobox
TRAF3Bgeecartilage tissue1.00infobox
TRAF3Bgeemonocyte1.00infobox
TRAF3BgeeBrodmann area 461.00infobox
TRAF3Bgeeappendix1.00infobox
TRAF3Bgeemiddle temporal gyrus1.00infobox
TRAF3Bgeegranulocyte1.00infobox
TRAF3Bgeepostcentral gyrus1.00infobox
TRAF3Bgeelymph node1.00infobox
TRAF3Bgeetesticle1.00infobox
TRAF3Bgeetibia1.00infobox
TRAF3BgeeCA3 field1.00infobox
TRAF3Bgeevestibular sensory epithelium1.00infobox
TRAF3Bgeeventral tegmental area1.00infobox
TRAF3BgeeEpithelium of choroid plexus1.00infobox
TRAF3Bgeecentral gray substance of midbrain1.00infobox
TRAF3Bgeeentorhinal cortex1.00infobox
TRAF3Bgeesubiculum1.00infobox
TRAF3Bgeedorsomedial hypothalamic nucleus1.00infobox
TRAF3Bgeelacrimal gland1.00infobox
TRAF3Bgeesuperior colliculus1.00infobox
TRAF3BioGPSMore reference expression data1.00infobox
TRAF3Chr.Chromosome 14 (human)1.00infobox
TRAF3Chr.Chromosome 12 (mouse)1.00infobox
TRAF3DatabasesNCBI: entry; OMA: entry1.00infobox
TRAF3End102,911,500 bp1.00infobox

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