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TRAF4

TNF receptor-associated factor 4 (TRAF4) also known as RING finger protein 83 (RNF83) is a protein that in humans is encoded by the TRAF4 gene.

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2.3.2.27
Aliases
TRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EOD, 2YUC, 3ZJB, 4K8U, 4M4E
Band
17q11.2 · 11|11 B5
Bgee
olfactory zone of nasal mucosa · right uterine tube · mucosa of transverse colon · right lobe of thyroid gland · minor salivary glands
BioGPS
More reference expression data

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Protein interactions

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Map overview Semantic statistics

TRAF4

Nodes15
Edges14
Triples103
Avg. degree1.87
Density0.133333
Components1

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TRAF4

Top relations

Gene ontology · 30
TRAF4 → activation of NF-kappaB-inducing kinase activity, apoptotic process, bicellular tight junction, cell junction, cytoplasm, cytoskeleton, DNA binding, identical protein binding, intracellular anatomical structure, membrane, metal ion binding, multicellular organism development, nucleus, perinuclear region of cytoplasm, plasma membrane, positive regulation of JNK cascade, positive regulation of protein homodimerization activity, positive regulation of protein kinase activity, protein binding, protein kinase binding
Bgee · 18
TRAF4 → embryo, epiblast, gallbladder, ganglionic eminence, genital tubercle, left lobe of thyroid gland, mandibular prominence, minor salivary glands, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, rectum, right kidney, right lobe of liver, right lobe of thyroid gland, right uterine tube, ventricular zone, yolk sac
RNA expression pattern · 18
TRAF4 → embryo, epiblast, gallbladder, ganglionic eminence, genital tubercle, left lobe of thyroid gland, mandibular prominence, minor salivary glands, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, rectum, right kidney, right lobe of liver, right lobe of thyroid gland, right uterine tube, ventricular zone, yolk sac
related to Protein interactions · 11
TRAF4 → Alternatively, MAPK8/JNK, NAD, NF-kappa, NF-κB, NOD-Like Receptors NOD1, NOD2, NOD2-RIP2, NTR, NTR/NTSR1, This
Band · 2
TRAF4 → 11|11 B5, 17q11.2
Chr. · 2
TRAF4 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
TRAF4 → 28,750,956 bp, 78,056,415 bp
2.3.2.27 · 1
TRAF4 → ↗
Aliases · 1
TRAF4 → TRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 4
Available structures · 1
TRAF4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EOD, 2YUC, 3ZJB, 4K8U, 4M4E

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Important terminology

protein tnf bp factor chr human band gene activation receptor chromosome 17 known receptors location traf proteins mouse nf-κb complex

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TRAF42.3.2.271.00infobox
TRAF4AliasesTRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 41.00infobox
TRAF4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EOD, 2YUC, 3ZJB, 4K8U, 4M4E1.00infobox
TRAF4Band17q11.21.00infobox
TRAF4Band11|11 B51.00infobox
TRAF4Bgeeolfactory zone of nasal mucosa1.00infobox
TRAF4Bgeeright uterine tube1.00infobox
TRAF4Bgeemucosa of transverse colon1.00infobox
TRAF4Bgeeright lobe of thyroid gland1.00infobox
TRAF4Bgeeminor salivary glands1.00infobox
TRAF4Bgeeleft lobe of thyroid gland1.00infobox
TRAF4Bgeeright lobe of liver1.00infobox
TRAF4Bgeeganglionic eminence1.00infobox
TRAF4Bgeegallbladder1.00infobox
TRAF4Bgeerectum1.00infobox
TRAF4Bgeeyolk sac1.00infobox
TRAF4Bgeeright kidney1.00infobox
TRAF4Bgeeneural tube1.00infobox
TRAF4Bgeeepiblast1.00infobox
TRAF4Bgeeventricular zone1.00infobox
TRAF4Bgeeembryo1.00infobox
TRAF4Bgeegenital tubercle1.00infobox
TRAF4Bgeemandibular prominence1.00infobox
TRAF4BioGPSMore reference expression data1.00infobox
TRAF4Chr.Chromosome 17 (human)1.00infobox
TRAF4Chr.Chromosome 11 (mouse)1.00infobox
TRAF4DatabasesNCBI: entry; OMA: entry1.00infobox
TRAF4End28,750,956 bp1.00infobox
TRAF4End78,056,415 bp1.00infobox
TRAF4EnsemblENSG000000766041.00infobox

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