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TNF receptor-associated factor 4 (TRAF4) also known as RING finger protein 83 (RNF83) is a protein that in humans is encoded by the TRAF4 gene.
The analysis highlights Protein interactions and Overview as prominent areas in the source structure around TRAF4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around TRAF4 shows recurring relationship patterns in the source. For example, TRAF4 → activation of NF-kappaB-inducing kinase activity, apoptotic process, bicellular tight junction, cell junction, cytoplasm, cytoskeleton, DNA binding, identical protein binding, intracellular anatomical structure, membrane, metal ion binding, multicellular organism development, nucleus, perinuclear region of cytoplasm, plasma membrane, positive regulation of JNK cascade, positive regulation of protein homodimerization activity, positive regulation of protein kinase activity, protein binding, protein kinase binding Another extracted example is TRAF4 → embryo, epiblast, gallbladder, ganglionic eminence, genital tubercle, left lobe of thyroid gland, mandibular prominence, minor salivary glands, mucosa of transverse colon, neural tube, olfactory zone of nasal mucosa, rectum, right kidney, right lobe of liver, right lobe of thyroid gland, right uterine tube, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
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protein tnf bp factor chr human band gene activation receptor chromosome 17 known receptors location traf proteins mouse nf-κb complex
TTTA extracted 102 structured relationships around TRAF4. Examples in this analysis include TRAF4 → 2.3.2.27 → ↗ and TRAF4 → Aliases → TRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 4. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TRAF4 | 2.3.2.27 | ↗ | 1.00 | infobox |
| TRAF4 | Aliases | TRAF4, CART1, MLN62, RNF83, TNF receptor associated factor 4 | 1.00 | infobox |
| TRAF4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EOD, 2YUC, 3ZJB, 4K8U, 4M4E | 1.00 | infobox |
| TRAF4 | Band | 17q11.2 | 1.00 | infobox |
| TRAF4 | Band | 11|11 B5 | 1.00 | infobox |
| TRAF4 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| TRAF4 | Bgee | right uterine tube | 1.00 | infobox |
| TRAF4 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| TRAF4 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| TRAF4 | Bgee | minor salivary glands | 1.00 | infobox |
| TRAF4 | Bgee | left lobe of thyroid gland | 1.00 | infobox |
| TRAF4 | Bgee | right lobe of liver | 1.00 | infobox |
| TRAF4 | Bgee | ganglionic eminence | 1.00 | infobox |
| TRAF4 | Bgee | gallbladder | 1.00 | infobox |
| TRAF4 | Bgee | rectum | 1.00 | infobox |
| TRAF4 | Bgee | yolk sac | 1.00 | infobox |
| TRAF4 | Bgee | right kidney | 1.00 | infobox |
| TRAF4 | Bgee | neural tube | 1.00 | infobox |
| TRAF4 | Bgee | epiblast | 1.00 | infobox |
| TRAF4 | Bgee | ventricular zone | 1.00 | infobox |
| TRAF4 | Bgee | embryo | 1.00 | infobox |
| TRAF4 | Bgee | genital tubercle | 1.00 | infobox |
| TRAF4 | Bgee | mandibular prominence | 1.00 | infobox |
| TRAF4 | BioGPS | More reference expression data | 1.00 | infobox |
| TRAF4 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| TRAF4 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| TRAF4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TRAF4 | End | 28,750,956 bp | 1.00 | infobox |
| TRAF4 | End | 78,056,415 bp | 1.00 | infobox |
| TRAF4 | Ensembl | ENSG00000076604 | 1.00 | infobox |
The concept neighborhoods around TRAF4 bring nearby vocabulary together. In this analysis, examples include Factor, Tnf and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TRAF4, one of the stronger structural bridges in this analysis connects TRAF4 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TRAF4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Protein interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TRAF4 · EN edition · Analysis: TopicsToTalkAbout
