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Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. Together with mood stabilizers, they are also a mainstay…
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antipsychotics effects used treatment atypical use drugs schizophrenia psychosis disorder symptoms also clozapine patients dementia may dopamine adverse bipolar risk
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Antipsychotic | Drugs.com | Drug Classes | 1.00 | infobox |
| Antipsychotic | MeSH | D014150 | 1.00 | infobox |
| Antipsychotic | Synonyms | Neuroleptics, major tranquilizers | 1.00 | infobox |
| Antipsychotic | Use | Principally: Schizophrenia, schizoaffective disorder, dementia, Tourette syndrome, bipolar disorder, irritability in autism spectrum disorder, borderline personality disorder | 1.00 | infobox |
| the PACE | instance of | 240 individuals aged 17 to 64 diagnosed with schizophrenia between 2002 and 2012 to arrive at this conclusion.Prevention of psychosis and symptom improvementTest batteries | 0.80 | text |
| lithium/valproate | instance of | often in conjunction with mood stabilizers | 0.80 | text |
| as a first-line treatment for manic | instance of | often in conjunction with mood stabilizers | 0.80 | text |
| mixed episodes associated with bipolar disorder | instance of | often in conjunction with mood stabilizers | 0.80 | text |
| the PACE | instance of | Prevention of psychosis and symptom improvementTest batteries | 0.80 | text |
| type II diabetes mellitus | instance of | which is more common in patients on clozapine.Metabolic syndrome and other metabolic problems | 0.80 | text |
| haloperidol | instance of | Mechanism of actionAntipsychotic drugs | 0.80 | text |
| chlorpromazine tend to block dopamine D2 receptors in the dopaminergic pathways of the brain | instance of | Mechanism of actionAntipsychotic drugs | 0.80 | text |
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