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Mitotic checkpoint serine/threonine-protein kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene.
The analysis highlights Geography and Regions as prominent areas in the source structure around BUB1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around BUB1 shows recurring relationship patterns in the source. For example, BUB1 → apoptotic process, ATP binding, cell cycle, cell division, cell population proliferation, chromosome, chromosome segregation, chromosome, centromeric region, cytosol, kinase activity, kinetochore, meiotic sister chromatid cohesion, centromeric, membrane, mitotic cell cycle checkpoint signaling, mitotic spindle assembly checkpoint signaling, nucleoplasm, nucleotide binding, nucleus, phosphorylation, protein binding Another extracted example is BUB1 → abdominal wall, bone marrow cell, dermis, epiblast, ganglionic eminence, genital tubercle, gonad, left testis, mandibular prominence, maxillary prominence, mucosa of transverse colon, otic placode, primitive streak, right testis, secondary oocyte, spermatid, tail of embryo, testicle, trabecular bone, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
kinase mitotic checkpoint human chromosome kinetochore also sac bp gene protein identified serine spindle chr band location activity phosphorylation aneuploidy
TTTA extracted 141 structured relationships around BUB1. Examples in this analysis include BUB1 → 2.7.11.1 → ↗ and BUB1 → Aliases → BUB1, BUB1A, BUB1L, hBUB1 mitotic checkpoint serine/threonine kinase. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| BUB1 | 2.7.11.1 | ↗ | 1.00 | infobox |
| BUB1 | Aliases | BUB1, BUB1A, BUB1L, hBUB1 mitotic checkpoint serine/threonine kinase | 1.00 | infobox |
| BUB1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LAH, 4A1G, 4QPM, 4R8Q, 5DMZ | 1.00 | infobox |
| BUB1 | Band | 2q13 | 1.00 | infobox |
| BUB1 | Band | 2 F1|2 62.1 cM | 1.00 | infobox |
| BUB1 | Bgee | ventricular zone | 1.00 | infobox |
| BUB1 | Bgee | gonad | 1.00 | infobox |
| BUB1 | Bgee | ganglionic eminence | 1.00 | infobox |
| BUB1 | Bgee | right testis | 1.00 | infobox |
| BUB1 | Bgee | left testis | 1.00 | infobox |
| BUB1 | Bgee | secondary oocyte | 1.00 | infobox |
| BUB1 | Bgee | testicle | 1.00 | infobox |
| BUB1 | Bgee | bone marrow cell | 1.00 | infobox |
| BUB1 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| BUB1 | Bgee | trabecular bone | 1.00 | infobox |
| BUB1 | Bgee | tail of embryo | 1.00 | infobox |
| BUB1 | Bgee | genital tubercle | 1.00 | infobox |
| BUB1 | Bgee | abdominal wall | 1.00 | infobox |
| BUB1 | Bgee | epiblast | 1.00 | infobox |
| BUB1 | Bgee | primitive streak | 1.00 | infobox |
| BUB1 | Bgee | otic placode | 1.00 | infobox |
| BUB1 | Bgee | mandibular prominence | 1.00 | infobox |
| BUB1 | Bgee | dermis | 1.00 | infobox |
| BUB1 | Bgee | maxillary prominence | 1.00 | infobox |
| BUB1 | Bgee | spermatid | 1.00 | infobox |
| BUB1 | BioGPS | More reference expression data | 1.00 | infobox |
| BUB1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| BUB1 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| BUB1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| BUB1 | End | 110,678,063 bp | 1.00 | infobox |
The concept neighborhoods around BUB1 bring nearby vocabulary together. In this analysis, examples include Also, Sac and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For BUB1, one of the stronger structural bridges in this analysis connects BUB1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around BUB1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — BUB1 · EN edition · Analysis: TopicsToTalkAbout