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CDC20: Measurement, Interactions & Cancer

The cell division cycle protein 20 homolog is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APC/CCdc20…

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CDC20 topic overview

The analysis highlights Measurement, Interactions and Cancer as prominent areas in the source structure around CDC20.

Related topics
37
Source areas
6
Connected nodes
43
Extracted relationships
172
Concept neighborhoods
14
Bridge connections
43

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 12 topics
Overview · 10 topics
Cancer · 7 topics
Structure · 5 topics
Spindle assembly checkpoint · 2 topics
Discovery · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CDC20, CDC20A, bA276H19.3, p55CDC, cell division cycle 20
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GGA, 4GGC, 4GGD, 4N14, 5G04
Band
1p34.2 · 4|4 D2.1
Bgee
oocyte · ventricular zone · secondary oocyte · embryo · ganglionic eminence
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Structure

Interactions

Spindle assembly checkpoint

Cancer

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CDC20 connects Entity context

The extracted context around CDC20 shows recurring relationship patterns in the source. For example, CDC20 → anaphase-promoting complex, anaphase-promoting complex binding, anaphase-promoting complex-dependent catabolic process, cell cycle, cell differentiation, cell division, centrosome, cytoplasm, cytoskeleton, cytosol, enzyme binding, histone deacetylase binding, microtubule organizing center, mitotic sister chromatid cohesion, mitotic spindle assembly, mitotic spindle assembly checkpoint signaling, nervous system development, nucleoplasm, nucleus, perinuclear region of cytoplasm Another extracted example is CDC20 → abdominal wall, embryo, endocardial cushion, epiblast, external carotid artery, ganglionic eminence, gonad, hair follicle, internal carotid artery, left testis, medial ganglionic eminence, mucosa of transverse colon, oocyte, primitive streak, renal corpuscle, right testis, secondary oocyte, trabecular bone, ureter, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

CDC20

Top relations

Gene ontology · 36
CDC20 → anaphase-promoting complex, anaphase-promoting complex binding, anaphase-promoting complex-dependent catabolic process, cell cycle, cell differentiation, cell division, centrosome, cytoplasm, cytoskeleton, cytosol, enzyme binding, histone deacetylase binding, microtubule organizing center, mitotic sister chromatid cohesion, mitotic spindle assembly, mitotic spindle assembly checkpoint signaling, nervous system development, nucleoplasm, nucleus, perinuclear region of cytoplasm
Bgee · 20
CDC20 → abdominal wall, embryo, endocardial cushion, epiblast, external carotid artery, ganglionic eminence, gonad, hair follicle, internal carotid artery, left testis, medial ganglionic eminence, mucosa of transverse colon, oocyte, primitive streak, renal corpuscle, right testis, secondary oocyte, trabecular bone, ureter, ventricular zone
RNA expression pattern · 20
CDC20 → abdominal wall, embryo, endocardial cushion, epiblast, external carotid artery, ganglionic eminence, gonad, hair follicle, internal carotid artery, left testis, medial ganglionic eminence, mucosa of transverse colon, oocyte, primitive streak, renal corpuscle, right testis, secondary oocyte, trabecular bone, ureter, ventricular zone
related to Cdh1 · 17
CDC20 → After, APC/C, APC/CCdc20, CDC20-homologue, Cdh1, During, G1, G1/S, G1/S Cdks, How, S-phase, S/M, S/M Cdks, S/M-Cdks, The APC/CCdc20, Their, This
related to Regulation · 15
CDC20 → APC/C, APC/CCdc20, Cdh1, Cdk, Cdk1, Cdks, G1, However, Importantly, In, Multiple, Once, S/M, The APC/CCdc20, Therefore
related to Spindle assembly checkpoint · 13
CDC20 → APC/CCdc20, Bub1, Bub3, BubR1, In, Mad2, Mad3, MCC, Moreover, SAC, The, The APC/CCdc20, This
related to Structure · 12
CDC20 → APC/CCdh1, C-box, C-terminus, Cry, In, KEN-box, Mad2-interacting, N-terminus, Near, The, The KEN-box, WD40
related to Interactions · 7
CDC20 → ANAPC7BUB1B, CDC16, CDC27, Cyclin A1, FBXO5, HDAC1, HDAC2
related to Discovery · 4
CDC20 → APC/C, Cdc, Hartwell, However
related to Cancer · 3
CDC20 → For, In, It

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

apc cell protein cycle anaphase complex ccdc20 cdh1 cdks gene cyclins human bp mitosis proteins chromosome chr band checkpoint thus

CDC20 relationships Subject–Predicate–Object triples

TTTA extracted 172 structured relationships around CDC20. Examples in this analysis include CDC20 → Aliases → CDC20, CDC20A, bA276H19.3, p55CDC, cell division cycle 20 and CDC20 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GGA, 4GGC, 4GGD, 4N14, 5G04. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CDC20AliasesCDC20, CDC20A, bA276H19.3, p55CDC, cell division cycle 201.00infobox
CDC20Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GGA, 4GGC, 4GGD, 4N14, 5G041.00infobox
CDC20Band1p34.21.00infobox
CDC20Band4|4 D2.11.00infobox
CDC20Bgeeoocyte1.00infobox
CDC20Bgeeventricular zone1.00infobox
CDC20Bgeesecondary oocyte1.00infobox
CDC20Bgeeembryo1.00infobox
CDC20Bgeeganglionic eminence1.00infobox
CDC20Bgeeleft testis1.00infobox
CDC20Bgeeright testis1.00infobox
CDC20Bgeemucosa of transverse colon1.00infobox
CDC20Bgeegonad1.00infobox
CDC20Bgeetrabecular bone1.00infobox
CDC20Bgeemedial ganglionic eminence1.00infobox
CDC20Bgeeprimitive streak1.00infobox
CDC20Bgeeabdominal wall1.00infobox
CDC20Bgeeureter1.00infobox
CDC20Bgeeendocardial cushion1.00infobox
CDC20Bgeeinternal carotid artery1.00infobox
CDC20Bgeeepiblast1.00infobox
CDC20Bgeerenal corpuscle1.00infobox
CDC20Bgeeexternal carotid artery1.00infobox
CDC20Bgeehair follicle1.00infobox
CDC20BioGPSMore reference expression data1.00infobox
CDC20Chr.Chromosome 1 (human)1.00infobox
CDC20Chr.Chromosome 4 (mouse)1.00infobox
CDC20DatabasesNCBI: entry; OMA: entry1.00infobox
CDC20End43,363,203 bp1.00infobox
CDC20End118,294,549 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CDC20 bring nearby vocabulary together. In this analysis, examples include Gene, Cycle and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CDC20
    • Gene
    • Cycle
    • Protein
    • Cell
    • Apc
    • Checkpoint
    • Human
    • Proteins
    • Cdh1
    • Division
    • Spindle
    • Location
  • cdc20
    • Gene
    • Cycle
    • Protein
    • Cell
    • Apc
    • Checkpoint
    • Human
    • Proteins
    • Cdh1
    • Division
    • Spindle
    • Location
  • anaphase promoting complex
    • Ccdc20
    • Apc
    • Important
    • Complex
    • Checkpoint
    • Chromatid
    • Activity
    • Separation
    • Mitosis
    • Proteins
    • Cycle
    • Protein
  • cell cycle
    • Cycle
    • Division
    • Protein
    • Mitosis
    • External
    • Gene
    • Spindle
    • Cdh1
    • Location
    • Role
    • Bp
    • Chr
  • chromatid
    • Separation
    • Sister
    • External
    • Complex
    • Division
    • Spindle
    • Activity
    • Band
    • Cohesin
    • Important
    • Location
    • Securin
  • spindle assembly checkpoint
    • External
    • Checkpoint
    • Division
    • Spindle
    • Location
    • Bp
    • Chr
    • Chromosome
    • Human
    • Gene
    • Sister
    • Cycle
  • gene
    • Location
    • Human
    • Bp
    • Chr
    • Chromosome
    • External
    • Spindle
    • Band
    • Checkpoint
    • Proteins
    • Protein
    • Chromatid
  • anaphase
    • Complex
    • Checkpoint
    • Separation
    • Important
    • Apc
    • Mitosis
    • Proteins
    • Ccdc20
    • Cdc20
    • Chromatid
    • Two
    • Activity

Connections between topic areas Semantic bridges

For CDC20, one of the stronger structural bridges in this analysis connects CDC20 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CDC20Interactions · splits 31 ⟂ 13
CDC20Overview · splits 33 ⟂ 11
CDC20Cancer · splits 36 ⟂ 8
CDC20Structure · splits 38 ⟂ 6
CDC20Spindle assembly checkpoint · splits 41 ⟂ 3

Map overview Semantic statistics

CDC20

Nodes44
Edges43
Triples172
Avg. degree1.95
Density0.045455
Components1

Source & methodology

TTTA analyzes the structure around CDC20 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Cancer, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CDC20 · EN edition · Analysis: TopicsToTalkAbout

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