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Mad2 (mitotic arrest deficient 2) is an essential spindle checkpoint protein. The spindle checkpoint system is a regulatory system that restrains progression through the metaphase-to-anaphase transition. The Mad2 gene was first identified in the yeast S. cerevisiae in a screen for genes which when mutated would confer sensitivity to microtubule poisons.…
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Explore the main themes, entities and connections around Mad2. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the full topic structure. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
See the strongest relationship patterns around the current topic before diving into the raw triples.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cdc20 checkpoint mad1 spindle protein binding transition open microtubule metaphase-to-anaphase anaphase kinetochores complex closed first cerevisiae sister bound proteins bind
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Mad2 | Alt. symbols | YJL030W | 1.00 | infobox |
| Mad2 | Chromosome | X: 0.39 - 0.39 Mb | 1.00 | infobox |
| Mad2 | Domains | InterPro | 1.00 | infobox |
| Mad2 | Entrez | 853422 | 1.00 | infobox |
| Mad2 | Organism | S. cerevisiae S288c | 1.00 | infobox |
| Mad2 | Orthologs | NCBI: entry; OMA: entry | 1.00 | infobox |
| Mad2 | RefSeq (mRNA) | NM_001181464 | 1.00 | infobox |
| Mad2 | RefSeq (Prot) | NP_012504 | 1.00 | infobox |
| Mad2 | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Mad2 | Structures | Swiss-model | 1.00 | infobox |
| Mad2 | Symbol | Mad2 | 1.00 | infobox |
| Mad2 | UniProt | P40958 | 1.00 | infobox |
| Mad2 | is a | stable complex and Cdc20 and Mad1 bind Mad 2 in the very same binding site | 0.90 | text |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.