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INCENP: Overview & Interactions

Inner centromere protein is a protein that in humans is encoded by the INCENP gene. It is a regulatory protein in the chromosome passenger complex (CPC). It is involved in regulation of the catalytic proteins Aurora B and Aurora C. It acts in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle.…

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INCENP topic overview

The analysis highlights Overview and Interactions as prominent areas in the source structure around INCENP.

Related topics
34
Source areas
2
Connected nodes
36
Extracted relationships
94
Concept neighborhoods
14
Bridge connections
36

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 29 topics
Interactions · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
INCENP, inner centromere protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QFA, 4AF3
Band
11q12.3 · 19 A|19 6.1 cM
Bgee
ventricular zone · ganglionic eminence · sural nerve · bone marrow cell · mucosa of esophagus
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How INCENP connects Entity context

The extracted context around INCENP shows recurring relationship patterns in the source. For example, INCENP → cell cycle, cell division, central element, chromocenter, chromosome, chromosome segregation, chromosome, centromeric region, cytoplasm, cytoskeleton, cytosol, kinetochore, lateral element, microtubule, midbody, mitotic cytokinesis, mitotic sister chromatid segregation, nuclear body, nucleoplasm, nucleus, pericentric heterochromatin Another extracted example is INCENP → bone marrow cell, cerebellar hemisphere, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, internal carotid artery, mucosa of esophagus, Paneth cell, prefrontal cortex, primary oocyte, primitive streak, renal corpuscle, right hemisphere of cerebellum, Rostral migratory stream, stromal cell of endometrium, sural nerve, testicle, ureter, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

INCENP

Top relations

Gene ontology · 25
INCENP → cell cycle, cell division, central element, chromocenter, chromosome, chromosome segregation, chromosome, centromeric region, cytoplasm, cytoskeleton, cytosol, kinetochore, lateral element, microtubule, midbody, mitotic cytokinesis, mitotic sister chromatid segregation, nuclear body, nucleoplasm, nucleus, pericentric heterochromatin
Bgee · 20
INCENP → bone marrow cell, cerebellar hemisphere, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, internal carotid artery, mucosa of esophagus, Paneth cell, prefrontal cortex, primary oocyte, primitive streak, renal corpuscle, right hemisphere of cerebellum, Rostral migratory stream, stromal cell of endometrium, sural nerve, testicle, ureter, ventricular zone
RNA expression pattern · 20
INCENP → bone marrow cell, cerebellar hemisphere, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, internal carotid artery, mucosa of esophagus, Paneth cell, prefrontal cortex, primary oocyte, primitive streak, renal corpuscle, right hemisphere of cerebellum, Rostral migratory stream, stromal cell of endometrium, sural nerve, testicle, ureter, ventricular zone
related to Interactions · 5
INCENP → CDCA8, H2AFZ, Survivin, The ARK, This
Band · 2
INCENP → 11q12.3, 19 A|19 6.1 cM
Chr. · 2
INCENP → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
INCENP → 62,153,169 bp, 9,876,915 bp
Aliases · 1
INCENP → INCENP, inner centromere protein
Available structures · 1
INCENP → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QFA, 4AF3
BioGPS · 1
INCENP → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

proteins centromere protein chromosome bp chr human band gene cell 11 broad inner cycle binding location midbody passenger involved aurora

INCENP relationships Subject–Predicate–Object triples

TTTA extracted 94 structured relationships around INCENP. Examples in this analysis include INCENP → Aliases → INCENP, inner centromere protein and INCENP → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QFA, 4AF3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
INCENPAliasesINCENP, inner centromere protein1.00infobox
INCENPAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2QFA, 4AF31.00infobox
INCENPBand11q12.31.00infobox
INCENPBand19 A|19 6.1 cM1.00infobox
INCENPBgeeventricular zone1.00infobox
INCENPBgeeganglionic eminence1.00infobox
INCENPBgeesural nerve1.00infobox
INCENPBgeebone marrow cell1.00infobox
INCENPBgeemucosa of esophagus1.00infobox
INCENPBgeecerebellar hemisphere1.00infobox
INCENPBgeeright hemisphere of cerebellum1.00infobox
INCENPBgeestromal cell of endometrium1.00infobox
INCENPBgeetesticle1.00infobox
INCENPBgeeprefrontal cortex1.00infobox
INCENPBgeePaneth cell1.00infobox
INCENPBgeecondyle1.00infobox
INCENPBgeefossa1.00infobox
INCENPBgeeureter1.00infobox
INCENPBgeeprimitive streak1.00infobox
INCENPBgeefetal liver hematopoietic progenitor cell1.00infobox
INCENPBgeerenal corpuscle1.00infobox
INCENPBgeeRostral migratory stream1.00infobox
INCENPBgeeprimary oocyte1.00infobox
INCENPBgeeinternal carotid artery1.00infobox
INCENPBioGPSMore reference expression data1.00infobox
INCENPChr.Chromosome 11 (human)1.00infobox
INCENPChr.Chromosome 19 (mouse)1.00infobox
INCENPDatabasesNCBI: entry; OMA: entry1.00infobox
INCENPEnd62,153,169 bp1.00infobox
INCENPEnd9,876,915 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around INCENP bring nearby vocabulary together. In this analysis, examples include Gene, Search and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • INCENP
    • Gene
    • Search
    • Protein
    • Inner
    • Location
    • Human
    • Bp
    • Chr
    • Chromosome
    • Aurora
    • Bundle
    • Complex
  • incenp
    • Gene
    • Search
    • Protein
    • Inner
    • Location
    • Human
    • Bp
    • Chr
    • Chromosome
    • Aurora
    • Bundle
    • Complex
  • cell cycle
    • Cycle
    • Stages
    • Protein
    • Centromere
    • Chromosome
    • Cytokinesis
    • End
    • Midbody
    • Mouse
    • Passenger
    • Regulation
    • Search
  • chromosome
    • Human
    • Bp
    • Chr
    • Location
    • Band
    • Gene
    • Complex
    • End
    • Mouse
    • Protein
    • Search
    • Cell
  • chromosome segregation
    • Human
    • Bp
    • Chr
    • Location
    • Band
    • Gene
    • Complex
    • End
    • Mouse
    • Protein
    • Search
    • Cell
  • gene
    • Location
    • Human
    • Incenp
    • Bp
    • Chr
    • End
    • Mouse
    • Search
    • Chromosome
    • Protein
    • Inner
    • Band
  • complex
    • Cytokinesis
    • End
    • Midbody
    • Mouse
    • Passenger
    • Protein
    • Regulation
    • Search
    • Survivin
    • Binding
    • Cycle
    • Location
  • centromere
    • Broad
    • Inner
    • Protein
    • Proteins
    • Stages
    • Cycle
    • Cell
    • Gene
    • Incenp
    • Include
    • Passenger
    • Search

Connections between topic areas Semantic bridges

For INCENP, one of the stronger structural bridges in this analysis connects INCENP with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
INCENPOverview · splits 7 ⟂ 30
INCENPInteractions · splits 31 ⟂ 6

Map overview Semantic statistics

INCENP

Nodes37
Edges36
Triples94
Avg. degree1.95
Density0.054054
Components1

Source & methodology

TTTA analyzes the structure around INCENP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — INCENP · EN edition · Analysis: TopicsToTalkAbout

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