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Protein phosphatase 2

Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. Its serine/threonine phosphatase activity has a broad substrate specificity and diverse cellular…

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Key facts & relationships

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Domains
InterPro
EC number
3.1.3.16
HGNC
9299
Locus
Chr. 5 q23-q31
NCBI gene
5515
OMIM
176915

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Drug discovery

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Map overview Semantic statistics

Protein phosphatase 2

Nodes21
Edges20
Triples11
Avg. degree1.9
Density0.095238
Components1

How this topic connects Entity context

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Protein phosphatase 2

Top relations

Domains · 1
Protein phosphatase 2 → InterPro
EC number · 1
Protein phosphatase 2 → 3.1.3.16
HGNC · 1
Protein phosphatase 2 → 9299
Locus · 1
Protein phosphatase 2 → Chr. 5 q23-q31
NCBI gene · 1
Protein phosphatase 2 → 5515
OMIM · 1
Protein phosphatase 2 → 176915
RefSeq · 1
Protein phosphatase 2 → NM_002715
Search for · 1
Protein phosphatase 2 → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Protein phosphatase 2 → Swiss-model
Symbol · 1
Protein phosphatase 2 → PPP2CA

Important terminology Word statistics

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Important terminology

pp2a protein subunit phosphatase activity catalytic manganese ppp2ca subunits pp2 also proteins active site gene n-terminus c-terminus methylated leucine microcystin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Protein phosphatase 2DomainsInterPro1.00infobox
Protein phosphatase 2EC number3.1.3.161.00infobox
Protein phosphatase 2HGNC92991.00infobox
Protein phosphatase 2LocusChr. 5 q23-q311.00infobox
Protein phosphatase 2NCBI gene55151.00infobox
Protein phosphatase 2OMIM1769151.00infobox
Protein phosphatase 2RefSeqNM_0027151.00infobox
Protein phosphatase 2Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Protein phosphatase 2StructuresSwiss-model1.00infobox
Protein phosphatase 2SymbolPPP2CA1.00infobox
Protein phosphatase 2UniProtP677751.00infobox

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