Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

BUB3

Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.

Role in the spindle assembly checkpoint, Function & Interactions

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around BUB3. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Role in the spindle assembly checkpoint

7 related topics

Function

6 related topics

Interactions

4 related topics

Structure

3 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BUB3, BUB3L, hmitotic checkpoint protein, BUB3 mitotic checkpoint protein
Band
10q26.13 · 7 F3|7 74.36 cM
Bgee
gingival epithelium · sperm · epithelium of nasopharynx · germinal epithelium · Epithelium of choroid plexus
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Role in the spindle assembly checkpoint

Structure

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

BUB3

Nodes34
Edges33
Triples138
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

BUB3

Top relations

Gene ontology · 22
BUB3 → anaphase-promoting complex-dependent catabolic process, attachment of spindle microtubules to kinetochore, bub1-bub3 complex, cell cycle, cell division, chromosome, chromosome segregation, chromosome, centromeric region, cytosol, kinetochore, meiosis, mitotic checkpoint complex, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint signaling, nucleoplasm, nucleus, protein binding, protein localization to kinetochore, regulation of chromosome segregation, regulation of mitotic cell cycle phase transition
Bgee · 20
BUB3 → abdominal wall, condyle, embryo, endocardial cushion, Epithelium of choroid plexus, epithelium of nasopharynx, ganglionic eminence, germinal epithelium, gingival epithelium, gonad, lymph node, mandibular prominence, maxillary prominence, medial ganglionic eminence, primitive streak, somite, sperm, stria vascularis, ventricular zone, vestibular sensory epithelium
RNA expression pattern · 20
BUB3 → abdominal wall, condyle, embryo, endocardial cushion, Epithelium of choroid plexus, epithelium of nasopharynx, ganglionic eminence, germinal epithelium, gingival epithelium, gonad, lymph node, mandibular prominence, maxillary prominence, medial ganglionic eminence, primitive streak, somite, sperm, stria vascularis, ventricular zone, vestibular sensory epithelium
related to Structure · 12
BUB3 → Both, Bub1, Gle2p-binding-sequence, GLEBS, Mad3, Mutation, Rae1, SAC, The, This, VAVE, WD40
related to Function · 11
BUB3 → After, BUB1, BUB2, For, If, Mad1, Mad2, Mad3, MPS1, The, This
related to Role in the spindle assembly checkpoint · 9
BUB3 → APC, APCCdc20, At, BubR1, Cdc20, Mad2-Cdc20, SAC, Securin, The
related to Interactions · 8
BUB3 → Additionally, BUB1B, Cdc20, HDAC1, Histone, Mad1-Bub1, Mad2, Mad3
related to Regulation · 7
BUB3 → After, Bub3-Cdc20, BubR1-Bub3, Mad2, Mad3, SAC, When
related to Clinical significance · 6
BUB3 → APC/C, BUB1, BUB1/BUB3, BUBR1, CDC20, MAD1L1
Band · 2
BUB3 → 10q26.13, 7 F3|7 74.36 cM

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

checkpoint complex protein bub1 spindle mitotic anaphase chromosome assembly sac bp human kinetochore mad3 gene chr band mad2 interaction proteins

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BUB3AliasesBUB3, BUB3L, hmitotic checkpoint protein, BUB3 mitotic checkpoint protein1.00infobox
BUB3Band10q26.131.00infobox
BUB3Band7 F3|7 74.36 cM1.00infobox
BUB3Bgeegingival epithelium1.00infobox
BUB3Bgeesperm1.00infobox
BUB3Bgeeepithelium of nasopharynx1.00infobox
BUB3Bgeegerminal epithelium1.00infobox
BUB3BgeeEpithelium of choroid plexus1.00infobox
BUB3Bgeeventricular zone1.00infobox
BUB3Bgeelymph node1.00infobox
BUB3Bgeeembryo1.00infobox
BUB3Bgeeganglionic eminence1.00infobox
BUB3Bgeegonad1.00infobox
BUB3Bgeevestibular sensory epithelium1.00infobox
BUB3Bgeeprimitive streak1.00infobox
BUB3Bgeemaxillary prominence1.00infobox
BUB3Bgeemandibular prominence1.00infobox
BUB3Bgeeabdominal wall1.00infobox
BUB3Bgeestria vascularis1.00infobox
BUB3Bgeemedial ganglionic eminence1.00infobox
BUB3Bgeeendocardial cushion1.00infobox
BUB3Bgeecondyle1.00infobox
BUB3Bgeesomite1.00infobox
BUB3BioGPSMore reference expression data1.00infobox
BUB3Chr.Chromosome 10 (human)1.00infobox
BUB3Chr.Chromosome 7 (mouse)1.00infobox
BUB3DatabasesNCBI: entry; OMA: entry1.00infobox
BUB3End123,170,467 bp1.00infobox
BUB3End131,173,624 bp1.00infobox
BUB3EnsemblENSG000001544731.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.