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Activity-regulated cytoskeleton-associated protein: Gene, Signaling & Protein

Activity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene. The gene is believed to derive from a retrotransposon. The protein is found in the neurons of tetrapods and other animals where it can form virus-like capsids that transport RNA between neurons.

Language: English [EN]
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Activity-regulated cytoskeleton-associated protein topic overview

The analysis highlights Gene, Signaling and Protein as prominent areas in the source structure around Activity-regulated cytoskeleton-associated protein.

Related topics
86
Source areas
8
Connected nodes
94
Extracted relationships
111
Concept neighborhoods
27
Bridge connections
94

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Gene · 22 topics
Overview · 20 topics
Signaling · 14 topics
Protein · 11 topics
Knockouts · 6 topics
Trafficking · 6 topics
Arc in insects · 4 topics
Behavioral effects · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ARC, Arg3.1, activity-regulated cytoskeleton-associated protein, activity regulated cytoskeleton associated protein, hArc
Band
8q24.3 · 15 D3|15 34.25 cM
Bgee
anterior pituitary · right frontal lobe · prefrontal cortex · cingulate gyrus · anterior cingulate cortex
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Trafficking

Protein

Knockouts

Signaling

Behavioral effects

Arc in insects

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Activity-regulated cytoskeleton-associated protein connects Entity context

The extracted context around Activity-regulated cytoskeleton-associated protein shows recurring relationship patterns in the source. For example, Activity-regulated cytoskeleton-associated protein → acrosomal vesicle, actin cytoskeleton, anterior/posterior pattern specification, cell cortex, cell junction, cell migration, cell projection, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytoskeleton organization, dendrite, dendritic spine, dendritic spine morphogenesis, early endosome membrane, endocytosis, endoderm development, endosome, extracellular vesicle, glutamatergic synapse Another extracted example is Activity-regulated cytoskeleton-associated protein → anterior cingulate cortex, anterior pituitary, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, ganglionic eminence, hippocampus proper, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatid, spermatocyte, striatum of neuraxis, superior frontal gyrus, testicle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Activity-regulated cytoskeleton-associated protein

Top relations

Gene ontology · 46
Activity-regulated cytoskeleton-associated protein → acrosomal vesicle, actin cytoskeleton, anterior/posterior pattern specification, cell cortex, cell junction, cell migration, cell projection, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytoskeleton organization, dendrite, dendritic spine, dendritic spine morphogenesis, early endosome membrane, endocytosis, endoderm development, endosome, extracellular vesicle, glutamatergic synapse
Bgee · 19
Activity-regulated cytoskeleton-associated protein → anterior cingulate cortex, anterior pituitary, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, ganglionic eminence, hippocampus proper, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatid, spermatocyte, striatum of neuraxis, superior frontal gyrus, testicle, ventricular zone
RNA expression pattern · 19
Activity-regulated cytoskeleton-associated protein → anterior cingulate cortex, anterior pituitary, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, ganglionic eminence, hippocampus proper, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatid, spermatocyte, striatum of neuraxis, superior frontal gyrus, testicle, ventricular zone
Band · 2
Activity-regulated cytoskeleton-associated protein → 15 D3|15 34.25 cM, 8q24.3
Chr. · 2
Activity-regulated cytoskeleton-associated protein → Chromosome 15 (mouse), Chromosome 8 (human)
End · 2
Activity-regulated cytoskeleton-associated protein → 142,614,479 bp, 74,544,419 bp
Aliases · 1
Activity-regulated cytoskeleton-associated protein → ARC, Arg3.1, activity-regulated cytoskeleton-associated protein, activity regulated cytoskeleton associated protein, hArc
BioGPS · 1
Activity-regulated cytoskeleton-associated protein → n/a
Databases · 1
Activity-regulated cytoskeleton-associated protein → NCBI: entry; OMA: entry
Ensembl · 1
Activity-regulated cytoskeleton-associated protein → ENSG00000198576

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

arc protein gene mrna human activity bp band factor chr chromosome sites translated activated important signaling neuronal synaptic regulation location

Activity-regulated cytoskeleton-associated protein relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around Activity-regulated cytoskeleton-associated protein. Examples in this analysis include Activity-regulated cytoskeleton-associated protein → Aliases → ARC, Arg3.1, activity-regulated cytoskeleton-associated protein, activity regulated cytoskeleton associated protein, hArc and Activity-regulated cytoskeleton-associated protein → Band → 8q24.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Activity-regulated cytoskeleton-associated proteinAliasesARC, Arg3.1, activity-regulated cytoskeleton-associated protein, activity regulated cytoskeleton associated protein, hArc1.00infobox
Activity-regulated cytoskeleton-associated proteinBand8q24.31.00infobox
Activity-regulated cytoskeleton-associated proteinBand15 D3|15 34.25 cM1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeanterior pituitary1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeright frontal lobe1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeprefrontal cortex1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeecingulate gyrus1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeanterior cingulate cortex1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeetesticle1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeedorsolateral prefrontal cortex1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeganglionic eminence1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeventricular zone1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeBrodmann area 91.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeprimary visual cortex1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeesuperior frontal gyrus1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeseminiferous tubule1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeespermatid1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeeprimary motor cortex1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeedentate gyrus of hippocampal formation granule cell1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeespermatocyte1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeehippocampus proper1.00infobox
Activity-regulated cytoskeleton-associated proteinBgeestriatum of neuraxis1.00infobox
Activity-regulated cytoskeleton-associated proteinBioGPSn/a1.00infobox
Activity-regulated cytoskeleton-associated proteinChr.Chromosome 8 (human)1.00infobox
Activity-regulated cytoskeleton-associated proteinChr.Chromosome 15 (mouse)1.00infobox
Activity-regulated cytoskeleton-associated proteinDatabasesNCBI: entry; OMA: entry1.00infobox
Activity-regulated cytoskeleton-associated proteinEnd142,614,479 bp1.00infobox
Activity-regulated cytoskeleton-associated proteinEnd74,544,419 bp1.00infobox
Activity-regulated cytoskeleton-associated proteinEnsemblENSG000001985761.00infobox
Activity-regulated cytoskeleton-associated proteinEntrez232371.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Activity-regulated cytoskeleton-associated protein bring nearby vocabulary together. In this analysis, examples include Mrna, Translated and Synaptic. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Activity-regulated cytoskeleton-associated protein
    • Mrna
    • Translated
    • Synaptic
    • Activity
    • Sites
    • Activation
    • Binding
    • Important
    • Regulation
    • Factor
    • Cytoskeleton
    • Learning
  • activity-regulated cytoskeleton-associated protein
    • Mrna
    • Translated
    • Synaptic
    • Activity
    • Sites
    • Activation
    • Binding
    • Important
    • Regulation
    • Factor
    • Cytoskeleton
    • Learning
  • protein
    • Mrna
    • Translated
    • Synaptic
    • Activity
    • Sites
    • Activation
    • Binding
    • Important
    • Regulation
    • Factor
    • Cytoskeleton
    • Learning
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Activity
    • Cytoskeleton
    • Mouse
    • Plasticity
    • Effects
    • Regulation
    • Band
  • mrna
    • Neuronal
    • Protein
    • Actin
    • Learning
    • Dendrites
    • Binding
    • Synaptic
    • Translated
    • Sites
    • Cellular
    • Cytoskeleton
    • Mouse
  • immediate-early gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Activity
    • Cytoskeleton
    • Mouse
    • Plasticity
    • Effects
    • Regulation
    • Band
  • protein synthesis inhibitors
    • Mrna
    • Translated
    • Synaptic
    • Activity
    • Sites
    • Activation
    • Binding
    • Important
    • Regulation
    • Factor
    • Cytoskeleton
    • Learning
  • actin
    • Neuronal
    • Cellular
    • Cytoskeleton
    • Learning
    • Mouse
    • Plasticity
    • Dendrites
    • Development
    • Localized
    • Activated
    • Binding
    • Chromosome

Connections between topic areas Semantic bridges

For Activity-regulated cytoskeleton-associated protein, one of the stronger structural bridges in this analysis connects Activity-regulated cytoskeleton-associated protein with Gene. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Activity-regulated cytoskeleton-associated proteinGene · splits 72 ⟂ 23
Activity-regulated cytoskeleton-associated proteinOverview · splits 74 ⟂ 21
Activity-regulated cytoskeleton-associated proteinSignaling · splits 80 ⟂ 15
Activity-regulated cytoskeleton-associated proteinProtein · splits 83 ⟂ 12
Activity-regulated cytoskeleton-associated proteinTrafficking · splits 88 ⟂ 7
Activity-regulated cytoskeleton-associated proteinKnockouts · splits 88 ⟂ 7
Activity-regulated cytoskeleton-associated proteinArc in insects · splits 90 ⟂ 5
Activity-regulated cytoskeleton-associated proteinBehavioral effects · splits 91 ⟂ 4

Map overview Semantic statistics

Activity-regulated cytoskeleton-associated protein

Nodes95
Edges94
Triples111
Avg. degree1.98
Density0.021053
Components1

Source & methodology

TTTA analyzes the structure around Activity-regulated cytoskeleton-associated protein to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Gene, Signaling & Protein, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Activity-regulated cytoskeleton-associated protein · EN edition · Analysis: TopicsToTalkAbout

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