Mitogen-activated protein kinase kinase

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Explore the main themes, entities and connections around Mitogen-activated protein kinase kinase. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Key facts & relationships

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BRENDA: enzyme data
EC no.: 2.7.12.2
ExPASy: NiceZyme view
KEGG: enzyme entry
MetaCyc: metabolic pathway
NCBI: proteins

Topics to explore

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Overview

Dual-specificity kinase
Enzyme
Phosphorylates Phosphorylation
MAP kinase Mitogen-activated protein kinase
EC Enzyme Commission number
MEK1
MEK2
MKK3
MKK4
MKK5
MKK6
MKK7
P38 P38 mitogen-activated protein kinases
JNK C-Jun N-terminal kinases
ERK Extracellular signal-regulated kinases

Role in melanoma

Apoptosis

As a drug target

MEK inhibitors MEK inhibitor

Advanced semantic analysis

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Map overview Semantic statistics

Mitogen-activated protein kinase kinase

Nodes21

Edges20

Triples11

Avg. degree1.9

Density0.095238

Components1

How this topic connects Entity context

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Mitogen-activated protein kinase kinase

Top relations

BRENDA · 1

Mitogen-activated protein kinase kinase → enzyme data

EC no. · 1

Mitogen-activated protein kinase kinase → 2.7.12.2

ExPASy · 1

Mitogen-activated protein kinase kinase → NiceZyme view

KEGG · 1

Mitogen-activated protein kinase kinase → enzyme entry

MetaCyc · 1

Mitogen-activated protein kinase kinase → metabolic pathway

NCBI · 1

Mitogen-activated protein kinase kinase → proteins

PDB structures · 1

Mitogen-activated protein kinase kinase → RCSB PDB PDBe PDBsum

PMC · 1

Mitogen-activated protein kinase kinase → articles

PubMed · 1

Mitogen-activated protein kinase kinase → articles

Rhea · 1

Mitogen-activated protein kinase kinase → reactions

Important terminology Word statistics

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Important terminology

mek kinase mek1 mek2 mapk mkk3 mkk4 mkk6 erk map2k enzyme also 12 mitogen-activated protein map signal transduction melanoma phosphorylates

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Mitogen-activated protein kinase kinase	BRENDA	enzyme data	1.00	infobox
Mitogen-activated protein kinase kinase	EC no.	2.7.12.2	1.00	infobox
Mitogen-activated protein kinase kinase	ExPASy	NiceZyme view	1.00	infobox
Mitogen-activated protein kinase kinase	KEGG	enzyme entry	1.00	infobox
Mitogen-activated protein kinase kinase	MetaCyc	metabolic pathway	1.00	infobox
Mitogen-activated protein kinase kinase	NCBI	proteins	1.00	infobox
Mitogen-activated protein kinase kinase	PDB structures	RCSB PDB PDBe PDBsum	1.00	infobox
Mitogen-activated protein kinase kinase	PMC	articles	1.00	infobox
Mitogen-activated protein kinase kinase	PubMed	articles	1.00	infobox
Mitogen-activated protein kinase kinase	Rhea	reactions	1.00	infobox
Mitogen-activated protein kinase kinase	Search	SearchPMCarticlesPubMedarticlesNCBIproteins	1.00	infobox

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Connections between topic areas Semantic bridges

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