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Serum response factor: Regions, Function & Interactions

Serum response factor, also known as SRF, is a transcription factor protein.

Language: English [EN]
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Serum response factor topic overview

The analysis highlights Regions, Function and Interactions as prominent areas in the source structure around Serum response factor.

Related topics
33
Source areas
4
Connected nodes
37
Extracted relationships
193
Concept neighborhoods
15
Bridge connections
37

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 16 topics
Interactions · 15 topics
Clinical significance · 1 topics
Overview · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SRF, MCM1, serum response factor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS
Band
6p21.1 · 17|17 C
Bgee
muscle layer of sigmoid colon · left uterine tube · popliteal artery · tibial arteries · right coronary artery
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Serum response factor connects Entity context

The extracted context around Serum response factor shows recurring relationship patterns in the source. For example, Serum response factor → actin cytoskeleton organization, actin filament organization, angiogenesis involved in wound healing, associative learning, bicellular tight junction assembly, branching involved in blood vessel morphogenesis, bronchus cartilage development, cardiac myofibril assembly, cardiac vascular smooth muscle cell differentiation, cell migration involved in sprouting angiogenesis, cell-cell adhesion, cell-matrix adhesion, cellular response to glucose stimulus, cellular senescence, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, contractile actin filament bundle assembly, cytoplasm, development of the heart Another extracted example is Serum response factor → body of uterus, dentate gyrus of hippocampal formation granule cell, gastric mucosa, genital tubercle, granulocyte, left uterine tube, lip, muscle layer of sigmoid colon, muscle of thigh, popliteal artery, primary visual cortex, right auricle of heart, right coronary artery, saphenous vein, skeletal muscle tissue, superior frontal gyrus, tail of embryo, thoracic aorta, tibial arteries, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Serum response factor

Top relations

Gene ontology · 103
Serum response factor → actin cytoskeleton organization, actin filament organization, angiogenesis involved in wound healing, associative learning, bicellular tight junction assembly, branching involved in blood vessel morphogenesis, bronchus cartilage development, cardiac myofibril assembly, cardiac vascular smooth muscle cell differentiation, cell migration involved in sprouting angiogenesis, cell-cell adhesion, cell-matrix adhesion, cellular response to glucose stimulus, cellular senescence, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, contractile actin filament bundle assembly, cytoplasm, development of the heart
Bgee · 20
Serum response factor → body of uterus, dentate gyrus of hippocampal formation granule cell, gastric mucosa, genital tubercle, granulocyte, left uterine tube, lip, muscle layer of sigmoid colon, muscle of thigh, popliteal artery, primary visual cortex, right auricle of heart, right coronary artery, saphenous vein, skeletal muscle tissue, superior frontal gyrus, tail of embryo, thoracic aorta, tibial arteries, zygote
RNA expression pattern · 20
Serum response factor → body of uterus, dentate gyrus of hippocampal formation granule cell, gastric mucosa, genital tubercle, granulocyte, left uterine tube, lip, muscle layer of sigmoid colon, muscle of thigh, popliteal artery, primary visual cortex, right auricle of heart, right coronary artery, saphenous vein, skeletal muscle tissue, superior frontal gyrus, tail of embryo, thoracic aorta, tibial arteries, zygote
related to Function · 13
Serum response factor → Agamous, Deficiens, Elk-1, In, Interaction, MADS, MAPK, MCM1, Serum, SRE, SRF, TCFs, This
related to Interactions · 13
Serum response factor → ASCC3, ATF6, CEBPB, CREB-binding, ELK4, GATA4, GTF2F1, GTF2I, Myogenin, NFYA, Nuclear, Promyelocytic, Serum
Band · 2
Serum response factor → 17|17 C, 6p21.1
Chr. · 2
Serum response factor → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Serum response factor → 43,181,506 bp, 46,867,101 bp
Aliases · 1
Serum response factor → SRF, MCM1, serum response factor
Available structures · 1
Serum response factor → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

srf serum response bp factor protein chr human band chromosome growth gene muscle transcription location also mouse regulation function external

Serum response factor relationships Subject–Predicate–Object triples

TTTA extracted 193 structured relationships around Serum response factor. Examples in this analysis include Serum response factor → Aliases → SRF, MCM1, serum response factor and Serum response factor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Serum response factorAliasesSRF, MCM1, serum response factor1.00infobox
Serum response factorAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS1.00infobox
Serum response factorBand6p21.11.00infobox
Serum response factorBand17|17 C1.00infobox
Serum response factorBgeemuscle layer of sigmoid colon1.00infobox
Serum response factorBgeeleft uterine tube1.00infobox
Serum response factorBgeepopliteal artery1.00infobox
Serum response factorBgeetibial arteries1.00infobox
Serum response factorBgeeright coronary artery1.00infobox
Serum response factorBgeesaphenous vein1.00infobox
Serum response factorBgeebody of uterus1.00infobox
Serum response factorBgeeright auricle of heart1.00infobox
Serum response factorBgeegastric mucosa1.00infobox
Serum response factorBgeethoracic aorta1.00infobox
Serum response factorBgeetail of embryo1.00infobox
Serum response factorBgeegenital tubercle1.00infobox
Serum response factorBgeezygote1.00infobox
Serum response factorBgeemuscle of thigh1.00infobox
Serum response factorBgeelip1.00infobox
Serum response factorBgeesuperior frontal gyrus1.00infobox
Serum response factorBgeegranulocyte1.00infobox
Serum response factorBgeeprimary visual cortex1.00infobox
Serum response factorBgeedentate gyrus of hippocampal formation granule cell1.00infobox
Serum response factorBgeeskeletal muscle tissue1.00infobox
Serum response factorBioGPSMore reference expression data1.00infobox
Serum response factorChr.Chromosome 6 (human)1.00infobox
Serum response factorChr.Chromosome 17 (mouse)1.00infobox
Serum response factorDatabasesNCBI: entry; OMA: entry1.00infobox
Serum response factorEnd43,181,506 bp1.00infobox
Serum response factorEnd46,867,101 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Serum response factor bring nearby vocabulary together. In this analysis, examples include Serum, Factor and Response. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Serum response factor
    • Serum
    • Factor
    • Response
    • Protein
    • Also
    • Element
    • Function
    • Mcm1
    • Promoter
    • Region
    • Search
    • Transcription
  • serum response factor
    • Serum
    • Factor
    • Response
    • Protein
    • Also
    • Function
    • Mcm1
    • Search
    • Transcription
    • Element
    • Location
    • Promoter
  • transcription factor protein
    • Response
    • Serum
    • Also
    • Factor
    • Function
    • Mcm1
    • Search
    • Transcription
    • Protein
    • Activity
    • Cell
    • Element
  • response element
    • Promoter
    • Region
    • Serum
    • Factor
    • Protein
    • Also
    • Element
    • Embryo
    • End
    • Expression
    • Formation
    • Function
  • cell cycle
    • Activity
    • Regulation
    • Growth
    • Element
    • Embryo
    • End
    • Expression
    • Formation
    • Function
    • Mcm1
    • Mesoderm
    • Mouse
  • cell differentiation
    • Activity
    • Regulation
    • Growth
    • Element
    • Embryo
    • End
    • Expression
    • Formation
    • Function
    • Mcm1
    • Mesoderm
    • Mouse
  • mitogen-activated protein kinase
    • Response
    • Serum
    • Activity
    • Cell
    • Element
    • Promoter
    • Region
    • Transcription
    • Genes
    • Regulation
    • Gene
    • Growth
  • creb-binding protein
    • Response
    • Serum
    • Activity
    • Cell
    • Element
    • Promoter
    • Region
    • Transcription
    • Genes
    • Regulation
    • Gene
    • Growth

Connections between topic areas Semantic bridges

For Serum response factor, one of the stronger structural bridges in this analysis connects Serum response factor with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Serum response factorFunction · splits 21 ⟂ 17
Serum response factorInteractions · splits 22 ⟂ 16

Map overview Semantic statistics

Serum response factor

Nodes38
Edges37
Triples193
Avg. degree1.95
Density0.052632
Components1

Source & methodology

TTTA analyzes the structure around Serum response factor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Serum response factor · EN edition · Analysis: TopicsToTalkAbout

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