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Glioblastoma

Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. Initial signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke.…

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Causes
Usually unclear
Diagnostic method
CT scan, MRI scan, tissue biopsy
Frequency
3 per 100,000 per year
Medication
Temozolomide, corticosteroids
Other names
Glioblastoma multiforme
Prevention
Unknown

Topics to explore

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Overview

Signs and symptoms

Risk factors

Pathogenesis

Diagnosis

Treatment

Prognosis

Epidemiology

History

Research

Advanced semantic analysis

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Map overview Semantic statistics

Glioblastoma

Nodes149
Edges148
Triples207
Avg. degree1.99
Density0.013423
Components1

How this topic connects Entity context

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Glioblastoma

Top relations

related to Diagnosis · 26
Glioblastoma → Astrocytomas, ATRX, Because, CT, Definitive, Distinguishing, EGFR, GBM, Glioblastomas, IDH-mutant, IDH-wild-type, IDH-wildtype, IDH1, IDH1 R132H, IDH2, IDH2 DNA, Imaging, In, MR, MRI
related to Intranasal drug delivery · 14
Glioblastoma → Among, Brazil, By, Direct, FDA, I/II, II, In, Most, NEO100, RNA, Similar, The, United States
related to Enhancer RNAs (eRNAs) · 13
Glioblastoma → AC003092, CYP1B1-AS1, Enhancer RNAs, For, JAK-STAT, Notably, Recent, RNAs, Silencing TMZR1-eRNA, STAT3, TMZ, TMZ-induced, TMZR1-eRNA
related to Gene therapy · 12
Glioblastoma → Although, Gene, III, LPLNP-PPT, Other, PEG, PPT, Scientists, Suicide, This, TRAIL, Using
related to Pathogenesis · 12
Glioblastoma → About, Because, CSF, GBM, GBMs, However, Malignant, More, Once, Since, The, Tumors
related to Glioblastoma classification · 11
Glioblastoma → Astrocytoma, Brain, Central Nervous System, IDH, In, Only, The, The World Health Organization, This, Tumors, WHO Classification
related to Molecular alterations · 9
Glioblastoma → Around, Classical, EGFR, Loss, NF1, PDGFRA, The, There, TP53
related to Radiotherapy · 8
Glioblastoma → As, Boron, GBM, Gy, It, Subsequent, Various, Whole-brain
related to Surgery · 8
Glioblastoma → An, Benefits, DNA, GBM, In, Other, Surgery, The
related to Symptomatic therapy · 8
Glioblastoma → Corticosteroids, Historically, Johnson, Neurosurgeons, Stevens, Supportive, The, Those

Important terminology Word statistics

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Important terminology

tumor cells survival brain treatment therapy cancer symptoms may gene temozolomide gbm clinical chemotherapy surgery diagnosis tumors risk radiation patients

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GlioblastomaCausesUsually unclear1.00infobox
GlioblastomaDiagnostic methodCT scan, MRI scan, tissue biopsy1.00infobox
GlioblastomaFrequency3 per 100,000 per year1.00infobox
GlioblastomaMedicationTemozolomide, corticosteroids1.00infobox
GlioblastomaOther namesGlioblastoma multiforme1.00infobox
GlioblastomaPreventionUnknown1.00infobox
GlioblastomaPrognosisLife expectancy ~12 months with treatment (5 year survival <10%)1.00infobox
GlioblastomaRisk factorsGenetic disorders (neurofibromatosis, Li–Fraumeni syndrome), previous radiation therapy1.00infobox
GlioblastomaSpecialtyNeuro-oncology, neurosurgery1.00infobox
GlioblastomaSymptomsInitially nonspecific, headaches, personality changes, nausea, symptoms similar to a stroke1.00infobox
GlioblastomaTreatmentSurgery, chemotherapy, radiation1.00infobox
GlioblastomaUsual onset~64 years old1.00infobox

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