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Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene.
The analysis highlights Clinical significance, Function and Interactions as prominent areas in the source structure around ATRX.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around ATRX shows recurring relationship patterns in the source. For example, ATRX → ATP binding, cellular response to DNA damage stimulus, cellular response to hydroxyurea, chromatin binding, chromatin organization, chromatin remodeling, chromo shadow domain binding, chromosome, chromosome organization involved in meiotic cell cycle, DNA binding, DNA damage response, signal transduction by p53 class mediator, DNA duplex unwinding, DNA helicase activity, DNA methylation, DNA recombination, DNA repair, DNA translocase activity, DNA-binding transcription factor activity, RNA polymerase II-specific, forebrain development, helicase activity Another extracted example is ATRX → Achilles tendon, Brodmann area 23, cerebellar vermis, ciliary body, condyle, endothelial cell, Epithelium of choroid plexus, epithelium of colon, fossa, genital tubercle, Gonadal ridge, lobe of cerebellum, medullary collecting duct, pineal gland, pylorus, Region I of hippocampus proper, sural nerve, tail of embryo, tibia, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene human bp chromosome chr band location chromatin mutations x-linked helicase also nuclear protein mouse syndrome histone remodeling ucsc ii
TTTA extracted 149 structured relationships around ATRX. Examples in this analysis include ATRX → Aliases → ATRX, ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX, MRX52, alpha thalassemia/mental retardation syndrome X-linked, chromatin remodeler, ATRX chromatin remodeler and ATRX → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JM1, 2LBM, 2LD1, 3QL9, 3QLA, 3QLC, 3QLN, 4W5A. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ATRX | Aliases | ATRX, ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX, MRX52, alpha thalassemia/mental retardation syndrome X-linked, chromatin remodeler, ATRX chromatin remodeler | 1.00 | infobox |
| ATRX | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JM1, 2LBM, 2LD1, 3QL9, 3QLA, 3QLC, 3QLN, 4W5A | 1.00 | infobox |
| ATRX | Band | Xq21.1 | 1.00 | infobox |
| ATRX | Band | X D|X 47.26 cM | 1.00 | infobox |
| ATRX | Bgee | endothelial cell | 1.00 | infobox |
| ATRX | Bgee | Achilles tendon | 1.00 | infobox |
| ATRX | Bgee | epithelium of colon | 1.00 | infobox |
| ATRX | Bgee | cerebellar vermis | 1.00 | infobox |
| ATRX | Bgee | Brodmann area 23 | 1.00 | infobox |
| ATRX | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| ATRX | Bgee | pylorus | 1.00 | infobox |
| ATRX | Bgee | tibia | 1.00 | infobox |
| ATRX | Bgee | sural nerve | 1.00 | infobox |
| ATRX | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| ATRX | Bgee | genital tubercle | 1.00 | infobox |
| ATRX | Bgee | tail of embryo | 1.00 | infobox |
| ATRX | Bgee | pineal gland | 1.00 | infobox |
| ATRX | Bgee | medullary collecting duct | 1.00 | infobox |
| ATRX | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| ATRX | Bgee | condyle | 1.00 | infobox |
| ATRX | Bgee | fossa | 1.00 | infobox |
| ATRX | Bgee | lobe of cerebellum | 1.00 | infobox |
| ATRX | Bgee | Gonadal ridge | 1.00 | infobox |
| ATRX | Bgee | ciliary body | 1.00 | infobox |
| ATRX | BioGPS | n/a | 1.00 | infobox |
| ATRX | Chr. | X chromosome (human) | 1.00 | infobox |
| ATRX | Chr. | X chromosome (mouse) | 1.00 | infobox |
| ATRX | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ATRX | End | 77,786,233 bp | 1.00 | infobox |
| ATRX | End | 104,973,009 bp | 1.00 | infobox |
The concept neighborhoods around ATRX bring nearby vocabulary together. In this analysis, examples include Gene, X-linked and Mutations. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For ATRX, one of the stronger structural bridges in this analysis connects ATRX with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around ATRX to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — ATRX · EN edition · Analysis: TopicsToTalkAbout