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Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which uses NAD+ as the electron acceptor and the other NADP+. Five isocitrate…
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idh1 isocitrate enzyme nadp gene mutations active ivosidenib mutation nadph human also dehydrogenase site two bp function one chromosome cytoplasm
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Isocitrate dehydrogenase 1 | 1.1.1.42 | ↗ | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Aliases | IDH1, HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, isocitrate dehydrogenase (NADP(+)) 1 | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1T09, 1T0L, 3INM, 3MAP, 3MAR, 3MAS, 4I3K, 4I3L, 4KZO, 4L03, 4L04, 4L06, 4UMX, 4UMY, 4XRX, 5DE1, 4XS3, 5K10,… | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Band | 2q34 | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Band | 1 C2- C3|1 32.91 cM | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | corpus epididymis | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | jejunal mucosa | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | right adrenal cortex | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | left adrenal gland | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | left adrenal cortex | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | secondary oocyte | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | duodenum | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | seminal vesicula | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | caput epididymis | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | cumulus cell | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | transitional epithelium of urinary bladder | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | right kidney | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | left lobe of liver | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | adrenal gland | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | human kidney | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | pyloric antrum | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | barrel cortex | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Bgee | superior cervical ganglion | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | BioGPS | n/a | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Isocitrate dehydrogenase 1 | End | 208,266,074 bp | 1.00 | infobox |
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