VDAC2

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VDAC2 topic overview

The analysis highlights Standards, Clinical significance and Interactions as prominent areas in the source structure around VDAC2.

Related topics: 34
Source areas: 4
Connected nodes: 38
Extracted relationships: 119
Concept neighborhoods: 12
Bridge connections: 38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 21 topics

Overview · 7 topics

Interactions · 4 topics

Function · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: VDAC2, POR, voltage dependent anion channel 2
Band: 10q22.2 · 14 A3|14 11.91 cM
Bgee: mucosa of esophagus · gastrocnemius muscle · left ventricle · ganglionic eminence · right auricle of heart
BioGPS: n/a
Chr.: Chromosome 10 (human) · Chromosome 14 (mouse)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Interact Protein-protein interaction
BAK Bcl-2 homologous antagonist killer
Parkin Parkin (ligase)
ENOS ENOS?action=edit&redlink=1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How VDAC2 connects Entity context

The extracted context around VDAC2 shows recurring relationship patterns in the source. For example, VDAC2 → acrosomal vesicle, anion transmembrane transport, anion transport, binding of sperm to zona pellucida, extracellular exosome, inorganic anion transport, integral component of membrane, ion transport, membrane, membrane raft, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrial outer membrane, mitochondrion, myelin sheath, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein polymerization, nucleotide binding, nucleus, pore complex Another extracted example is VDAC2 → apex of heart, atrioventricular valve, endocardial cushion, epithelium of stomach, ganglionic eminence, gastrocnemius muscle, left ventricle, migratory enteric neural crest cell, mucosa of esophagus, mucous cell of stomach, muscle layer of sigmoid colon, muscle of thigh, pyloric antrum, rectum, right auricle of heart, right ventricle, seminiferous tubule, spermatid, vagina, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 27

VDAC2 → acrosomal vesicle, anion transmembrane transport, anion transport, binding of sperm to zona pellucida, extracellular exosome, inorganic anion transport, integral component of membrane, ion transport, membrane, membrane raft, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrial outer membrane, mitochondrion, myelin sheath, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein polymerization, nucleotide binding, nucleus, pore complex

Bgee · 20

VDAC2 → apex of heart, atrioventricular valve, endocardial cushion, epithelium of stomach, ganglionic eminence, gastrocnemius muscle, left ventricle, migratory enteric neural crest cell, mucosa of esophagus, mucous cell of stomach, muscle layer of sigmoid colon, muscle of thigh, pyloric antrum, rectum, right auricle of heart, right ventricle, seminiferous tubule, spermatid, vagina, vastus lateralis muscle

RNA expression pattern · 20

related to Clinical significance · 13

VDAC2 → Although, An, Apoptosis, DNA, In, It, Programmed, ROS, The, The VDAC, The VDAC2, These, This

related to Function · 6

VDAC2 → ATP, Bcl-2, In, MPTP, VDAC, VDACs

related to Structure · 5

VDAC2 → In, N-terminal, The, VDAC, VDACs

related to External links · 3

VDAC2 → Medicine Medical Subject Headings, MeSH, National Library

Band · 2

VDAC2 → 10q22.2, 14 A3|14 11.91 cM

Chr. · 2

VDAC2 → Chromosome 10 (human), Chromosome 14 (mouse)

End · 2

VDAC2 → 21,895,947 bp, 75,231,448 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mitochondrial apoptosis cell protein human bp also death vdacs channel chromosome 10 membrane chr band gene apoptotic pathway vdac isoforms

VDAC2 relationships Subject–Predicate–Object triples

TTTA extracted 119 structured relationships around VDAC2. Examples in this analysis include VDAC2 → Aliases → VDAC2, POR, voltage dependent anion channel 2 and VDAC2 → Band → 10q22.2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
VDAC2	Aliases	VDAC2, POR, voltage dependent anion channel 2	1.00	infobox
VDAC2	Band	10q22.2	1.00	infobox
VDAC2	Band	14 A3\|14 11.91 cM	1.00	infobox
VDAC2	Bgee	mucosa of esophagus	1.00	infobox
VDAC2	Bgee	gastrocnemius muscle	1.00	infobox
VDAC2	Bgee	left ventricle	1.00	infobox
VDAC2	Bgee	ganglionic eminence	1.00	infobox
VDAC2	Bgee	right auricle of heart	1.00	infobox
VDAC2	Bgee	muscle of thigh	1.00	infobox
VDAC2	Bgee	apex of heart	1.00	infobox
VDAC2	Bgee	muscle layer of sigmoid colon	1.00	infobox
VDAC2	Bgee	rectum	1.00	infobox
VDAC2	Bgee	vagina	1.00	infobox
VDAC2	Bgee	epithelium of stomach	1.00	infobox
VDAC2	Bgee	spermatid	1.00	infobox
VDAC2	Bgee	endocardial cushion	1.00	infobox
VDAC2	Bgee	atrioventricular valve	1.00	infobox
VDAC2	Bgee	seminiferous tubule	1.00	infobox
VDAC2	Bgee	mucous cell of stomach	1.00	infobox
VDAC2	Bgee	pyloric antrum	1.00	infobox
VDAC2	Bgee	right ventricle	1.00	infobox
VDAC2	Bgee	migratory enteric neural crest cell	1.00	infobox
VDAC2	Bgee	vastus lateralis muscle	1.00	infobox
VDAC2	BioGPS	n/a	1.00	infobox
VDAC2	Chr.	Chromosome 10 (human)	1.00	infobox
VDAC2	Chr.	Chromosome 14 (mouse)	1.00	infobox
VDAC2	Databases	NCBI: entry; OMA: entry	1.00	infobox
VDAC2	End	75,231,448 bp	1.00	infobox
VDAC2	End	21,895,947 bp	1.00	infobox
VDAC2	Ensembl	ENSG00000165637	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around VDAC2 bring nearby vocabulary together. In this analysis, examples include Mitochondrial, Isoforms and Circulation. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

VDAC2
- Mitochondrial
- Isoforms
- Circulation
- Ibd
- Immune
- Pulmonary
- Anion
- Function
- Gene
- Chromosome
- Human
- Outer
vdac2
- Mitochondrial
- Isoforms
- Circulation
- Ibd
- Immune
- Pulmonary
- Anion
- Function
- Gene
- Chromosome
- Human
- Outer
protein
- Voltage-dependent
- Vdac2
- Anion
- Enos
- Gene
- Chromosome
- Human
- Isoforms
- Outer
- Vdac
- Membrane
- Cell
voltage-dependent anion channel
- Anion
- Channel
- Voltage-dependent
- Gene
- Human
- Protein
- Chromosome
- Location
- Structure
- Function
- Bp
- Chr
outer mitochondrial membrane
- Outer
- Membrane
- Mitochondrial
- Sperm
- Transport
- Vdac
- Vdacs
- Vdac2
- Apoptosis
- Apoptotic
- Pathway
- Protein
apoptotic bodies
- Pathway
- Cell
- Death
- Vdac
- Mitochondrial
- Membrane
- Cardiac
- Location
- Response
- Structure
- Transport
- Band
gene
- Chromosome
- Location
- Bp
- Chr
- Human
- Structure
- Anion
- Band
- Function
- Protein
- Transport
- Voltage-dependent
mitochondrial
- Membrane
- Outer
- Vdacs
- Vdac2
- Apoptosis
- Vdac
- Apoptotic
- Pathway
- Cardiac
- Transport
- Function
- May

Connections between topic areas Semantic bridges

For VDAC2, one of the stronger structural bridges in this analysis connects VDAC2 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

VDAC2 — Clinical significance · splits 17 ⟂ 22

VDAC2 — Overview · splits 31 ⟂ 8

VDAC2 — Interactions · splits 34 ⟂ 5

VDAC2 — Function · splits 36 ⟂ 3

Map overview Semantic statistics

VDAC2

Nodes39

Edges38

Triples119

Avg. degree1.95

Density0.051282

Components1

Source & methodology

TTTA analyzes the structure around VDAC2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Clinical significance & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — VDAC2 · EN edition · Analysis: TopicsToTalkAbout