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Hexokinase I, also known as hexokinase A and HK1, is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6-phosphate (G6P), the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria.…
Function, Clinical significance & Structure
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hexokinase gene mitochondrial protein bp glucose metabolism also hk1 function g6p chromosome 10 c-terminal isoforms chr human band cell atp
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Hexokinase I | 2.7.1.1 | ↗ | 1.00 | infobox |
| Hexokinase I | Aliases | HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, hexokinase 1, HK, hexokinase, RP79, NEDVIBA | 1.00 | infobox |
| Hexokinase I | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CZA, 1DGK, 1HKB, 1HKC, 1QHA, 4F9O, 4FOE, 4FOI, 4FPA, 4FPB | 1.00 | infobox |
| Hexokinase I | Band | 10q22.1 | 1.00 | infobox |
| Hexokinase I | Band | 10 B4|10 32.37 cM | 1.00 | infobox |
| Hexokinase I | Bgee | cerebellar vermis | 1.00 | infobox |
| Hexokinase I | Bgee | mucosa of pharynx | 1.00 | infobox |
| Hexokinase I | Bgee | pons | 1.00 | infobox |
| Hexokinase I | Bgee | cardiac muscle tissue of right atrium | 1.00 | infobox |
| Hexokinase I | Bgee | body of tongue | 1.00 | infobox |
| Hexokinase I | Bgee | spinal ganglia | 1.00 | infobox |
| Hexokinase I | Bgee | parotid gland | 1.00 | infobox |
| Hexokinase I | Bgee | sperm | 1.00 | infobox |
| Hexokinase I | Bgee | myocardium of left ventricle | 1.00 | infobox |
| Hexokinase I | Bgee | superior vestibular nucleus | 1.00 | infobox |
| Hexokinase I | Bgee | neural layer of retina | 1.00 | infobox |
| Hexokinase I | Bgee | seminiferous tubule | 1.00 | infobox |
| Hexokinase I | Bgee | spermatid | 1.00 | infobox |
| Hexokinase I | Bgee | subiculum | 1.00 | infobox |
| Hexokinase I | Bgee | piriform cortex | 1.00 | infobox |
| Hexokinase I | Bgee | retinal pigment epithelium | 1.00 | infobox |
| Hexokinase I | Bgee | dorsal tegmental nucleus | 1.00 | infobox |
| Hexokinase I | Bgee | central gray substance of midbrain | 1.00 | infobox |
| Hexokinase I | Bgee | dorsomedial hypothalamic nucleus | 1.00 | infobox |
| Hexokinase I | Bgee | superior colliculus | 1.00 | infobox |
| Hexokinase I | BioGPS | More reference expression data | 1.00 | infobox |
| Hexokinase I | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Hexokinase I | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| Hexokinase I | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Hexokinase I | End | 69,401,884 bp | 1.00 | infobox |
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