P2Y12

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P2Y12 antagonists

Clopidogrel Prasugrel Ticagrelor Cangrelor Antiplatelet

11 related topics

Overview

Chemoreceptor Adenosine diphosphate Gi G protein-coupled Purinergic receptors

18 related topics

Key facts & relationships

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Aliases: P2RY12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999, purinergic receptor P2Y12
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NTJ, 4PXZ, 4PY0
Band: 3q25.1 · 3|3 D
Bgee: inferior ganglion of vagus nerve · superior vestibular nucleus · ventral tegmental area · subthalamic nucleus · Brodmann area 46
BioGPS: n/a
Chr.: Chromosome 3 (human) · Chromosome 3 (mouse)

Topics to explore

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Overview

Chemoreceptor
Adenosine diphosphate
Gi Gi alpha subunit
G protein-coupled G protein-coupled receptor
Purinergic receptors
P2Y receptor
Adenosine
Uridine
Nucleotides Nucleotide
Platelet aggregation
Biological target
Thromboembolisms Thrombosis
Purinergic signaling
Protein
Blood
Platelets Platelet
Clotting Coagulation
Microglia

P2Y12 antagonists

Advanced semantic analysis

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Map overview Semantic statistics

Nodes32

Edges31

Triples118

Avg. degree1.94

Density0.0625

Components1

How this topic connects Entity context

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P2Y12

Top relations

Gene ontology · 40

P2Y12 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, basal plasma membrane, blood coagulation, calcium ion transmembrane transport, caveola, cell projection organization, cell surface, cellular response to ATP, cellular response to organic cyclic compound, external side of plasma membrane, G protein-coupled adenosine receptor activity, G protein-coupled adenosine receptor signaling pathway, G protein-coupled ADP receptor activity, G protein-coupled purinergic nucleotide receptor activity, G protein-coupled purinergic nucleotide receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, glial cell migration, guanyl-nucleotide exchange factor activity

Bgee · 20

P2Y12 → blood, Brodmann area 46, corpus callosum, dentate gyrus of hippocampal formation granule cell, globus pallidus, inferior ganglion of vagus nerve, lumbar subsegment of spinal cord, monocyte, morula, olfactory tubercle, optic nerve, primary visual cortex, Region I of hippocampus proper, spinal cord, spinal ganglia, subthalamic nucleus, superior frontal gyrus, superior vestibular nucleus, testicle, ventral tegmental area

RNA expression pattern · 20

has treatment · 13

P2Y12 → Canadian, European, In, NSTEMI, On, PCI, ST-elevation, ST-segment, STEMI, They, Though, Thus, US

Band · 2

P2Y12 → 3q25.1, 3|3 D

Chr. · 2

P2Y12 → Chromosome 3 (human), Chromosome 3 (mouse)

End · 2

P2Y12 → 151,384,753 bp, 59,170,292 bp

Aliases · 1

P2Y12 → P2RY12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999, purinergic receptor P2Y12

Available structures · 1

P2Y12 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NTJ, 4PXZ, 4PY0

BioGPS · 1

P2Y12 → n/a

Important terminology Word statistics

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Important terminology

receptor bp chr human band purinergic gene adenosine chromosome adp found coronary treatment external clotting location antiplatelet 12 exclusively prasugrel

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
P2Y12	Aliases	P2RY12, ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999, purinergic receptor P2Y12	1.00	infobox
P2Y12	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NTJ, 4PXZ, 4PY0	1.00	infobox
P2Y12	Band	3q25.1	1.00	infobox
P2Y12	Band	3\|3 D	1.00	infobox
P2Y12	Bgee	inferior ganglion of vagus nerve	1.00	infobox
P2Y12	Bgee	superior vestibular nucleus	1.00	infobox
P2Y12	Bgee	ventral tegmental area	1.00	infobox
P2Y12	Bgee	subthalamic nucleus	1.00	infobox
P2Y12	Bgee	Brodmann area 46	1.00	infobox
P2Y12	Bgee	monocyte	1.00	infobox
P2Y12	Bgee	corpus callosum	1.00	infobox
P2Y12	Bgee	spinal ganglia	1.00	infobox
P2Y12	Bgee	spinal cord	1.00	infobox
P2Y12	Bgee	testicle	1.00	infobox
P2Y12	Bgee	globus pallidus	1.00	infobox
P2Y12	Bgee	blood	1.00	infobox
P2Y12	Bgee	lumbar subsegment of spinal cord	1.00	infobox
P2Y12	Bgee	superior frontal gyrus	1.00	infobox
P2Y12	Bgee	primary visual cortex	1.00	infobox
P2Y12	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
P2Y12	Bgee	morula	1.00	infobox
P2Y12	Bgee	optic nerve	1.00	infobox
P2Y12	Bgee	olfactory tubercle	1.00	infobox
P2Y12	Bgee	Region I of hippocampus proper	1.00	infobox
P2Y12	BioGPS	n/a	1.00	infobox
P2Y12	Chr.	Chromosome 3 (human)	1.00	infobox
P2Y12	Chr.	Chromosome 3 (mouse)	1.00	infobox
P2Y12	Databases	NCBI: entry; OMA: entry	1.00	infobox
P2Y12	End	151,384,753 bp	1.00	infobox
P2Y12	End	59,170,292 bp	1.00	infobox

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